Chloranil - 98%, high purity , CAS No.118-75-2

  • ≥98%
Item Number
T105285
Grouped product items
SKUSizeAvailabilityPrice Qty
T105285-25g
25g
In stock
$11.90
T105285-100g
100g
In stock
$31.90
T105285-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$109.90

Basic Description

Synonyms2,3,5,6-Tetrachloro-p-benzoquinone | DivK1c_006946 | EN300-18125 | Spectrum5_001386 | Spergon | 2,5,6-Tetrachloroquinone | 4-Chloranil | Tox21_303021 | CS-0013526 | D72499 | DTXCID20266 | Spergon I | Tetrachloro-p-quinone | p-Benzoquinone,3,5,6-tetrachlor
Specifications & Purity≥98%
Shipped InNormal
Product Description

A reagent for the dehydrogenation of hydroaromatic compounds.
1.Synthesis of dibenzofurans via oxidative cyclization; 2.Undergoes photoinduced cycloaddition reactions with stilbene derivatives and α,β-unsaturated carbonyl compounds; 3.Fluorescence quencher.

Associated Targets(Human)

CES1 Tchem Liver carboxylesterase 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CES2 Tchem Cocaine esterase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ACHE Tclin Acetylcholinesterase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
BCHE Tclin Cholinesterase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CES2 Tchem Carboxylesterase 2 (583 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CES1 Tchem Acyl coenzyme A:cholesterol acyltransferase (1029 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MRC5 (9203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichoplusia ni (986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
groL GroEL/GroES (1042 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180768
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180768
IUPAC Name 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione
INCHI InChI=1S/C6Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11
InChi Key UGNWTBMOAKPKBL-UHFFFAOYSA-N
Canonical SMILES C1(=C(C(=O)C(=C(C1=O)Cl)Cl)Cl)Cl
Isomeric SMILES C1(=C(C(=O)C(=C(C1=O)Cl)Cl)Cl)Cl
WGK Germany 2
RTECS DK6825000
PubChem CID 8371
Molecular Weight 245.88
Beilstein 393006
Reaxy-Rn 393006

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
J2411476Certificate of AnalysisOct 18, 2024 T105285
J2411468Certificate of AnalysisOct 15, 2024 T105285
A2429421Certificate of AnalysisJul 04, 2022 T105285
B2303783Certificate of AnalysisJul 04, 2022 T105285
B2303786Certificate of AnalysisJul 04, 2022 T105285
H2412486Certificate of AnalysisJul 04, 2022 T105285
J2215474Certificate of AnalysisJul 04, 2022 T105285
J2215503Certificate of AnalysisJul 04, 2022 T105285
J2215528Certificate of AnalysisJul 04, 2022 T105285
C2201019Certificate of AnalysisMar 05, 2021 T105285
D2113244Certificate of AnalysisMar 05, 2021 T105285

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Chemical and Physical Properties

SolubilitySoluble in ether and acetone. Slightly soluble in chloroform, dimethylformamide, solvent naphtha, benzene, carbon disulfide and carbon tetrachloride. Insoluble in water, cold petroleum ether, methanol, dibutyl phthalate and cold alcohol.
SensitivityLight sensitive
Melt Point(°C)290°C

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 2
RTECS DK6825000
Reaxy-Rn 393006
Merck Index 2078

Related Documents

Citations of This Product

1. Yongsheng Chen,Gaoyan Wang,Hong Wang,Chaohua Cheng,Gonggu Zang,Xinbo Guo,Rui Hai Liu.  (2014-09-23)  Phytochemical profiles and antioxidant activities in six species of ramie leaves..  PloS one,  ((9)): (e108140-e108140).  [PMID:25243741]
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4. Yiran Wang, Xinyu Yang, Xueting Lu, Xiaonian Cao, Ling Ao, Lele Ma, Caihong Shen, Yongqian Fu, Yaqiong Yang.  (2024)  BODIPY-labeled aptasensor based on multi-walled carbon nanotubes as the quencher for “off–on” detection of catechin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  306  (24): (123597).  [PMID:37925958] [10.1016/j.saa.2023.123597]
5. Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan.  (2024)  Highly bright stable organic radicals encapsulated by amphiphilic polypeptide for efficient near-infrared phototheranostics.  TALANTA,  266  (124948).  [PMID:37459788] [10.1016/j.talanta.2023.124948]
6. Cuiping Li, Mengfan Pang, Yaping Li, Lirong Han, Yajiao Fan, Xuelian Xin, Xian Zhang, Ning Zhang, Yan Qin.  (2023)  Protective effect of vitamin C against tetrachlorobenzoquinone-induced 5-hydroxymethylation-dependent apoptosis in HepG2 cells mainly via the mitochondrial apoptosis pathway.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  260  (115097).  [PMID:37271103] [10.1016/j.ecoenv.2023.115097]
7. Bingwei Yang, Zhishuai Ye, Xiangyu Zhu, Rongchong Huang, Erqun Song, Yang Song.  (2023)  The redox activity of polychlorinated biphenyl quinone metabolite orchestrates its pro-atherosclerosis effect via CAV1 phosphorylation.  JOURNAL OF HAZARDOUS MATERIALS,  457  (131697).  [PMID:37257380] [10.1016/j.jhazmat.2023.131697]
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12. Ya-Ting Gao, Bin-Bin Chen, Lei Jiang, Jian Lv, Shuai Chang, Yue Wang, Ruo-Can Qian, Da-Wei Li, Mahmoud Elsayed Hafez.  (2021)  Dual-Emitting Carbonized Polymer Dots Synthesized at Room Temperature for Ratiometric Fluorescence Sensing of Vitamin B12.  ACS Applied Materials & Interfaces,  13  (42): (50228–50235).  [PMID:34651499] [10.1021/acsami.1c12993]
13. Yan Chen, Zhao Mo, Xingtong Zhu, Qingxiang Xu, Zhaoli Xue, Henan Li, Hui Xu, Long Zhao.  (2021)  Facilitated interfacial charge separation using triphenylamine-zinc porphyrin dyad-sensitized TiO2 nanoparticles for photocatalysis.  JOURNAL OF ALLOYS AND COMPOUNDS,  889  (161795).  [PMID:] [10.1016/j.jallcom.2021.161795]
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16. Xuying Lv, Zixuan Liu, Lei Xu, Erqun Song, Yang Song.  (2021)  Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop.  ENVIRONMENTAL POLLUTION,  268  (115921).  [PMID:33187846] [10.1016/j.envpol.2020.115921]
17. Long Zhao, Qingxiang Xu, Zhiwen Shao, Yan Chen, Zhaoli Xue, Henan Li, Jianming Zhang.  (2020)  Enhanced Oxygen Reduction Reaction Performance Using Intermolecular Forces Coupled with More Exposed Molecular Orbitals of Triphenylamine in Co-porphyrin Electrocatalysts.  ACS Applied Materials & Interfaces,  12  (41): (45976–45986).  [PMID:32975398] [10.1021/acsami.0c11742]
18. Lu Yan, Chang Zhaosen, Zhang Shizhen, Wang Shunli, Chen Qi, Feng Lijuan, Sui Zhuyin.  (2020)  Porous organic polymers containing zinc porphyrin and phosphonium bromide as bifunctional catalysts for conversion of carbon dioxide.  JOURNAL OF MATERIALS SCIENCE,  55  (26): (11856-11869).  [PMID:] [10.1007/s10853-020-04851-9]
19. Bowen Xiang, Yudong Xue, Zhiyong Liu, Jia Tian, Holger Frey, Yun Gao, Weian Zhang.  (2020)  Water-soluble hyperbranched polyglycerol photosensitizer for enhanced photodynamic therapy.  Polymer Chemistry,  11  (23): (3913-3921).  [PMID:] [10.1039/D0PY00431F]
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22. Xiaoqi Chen, Wei Wang, Cheng Wang, Zijia Liu, Qi Sun, Dongmei Wang.  (2019)  Quality evaluation and chemometric discrimination of Zanthoxylum bungeanum Maxim leaves based on flavonoids profiles, bioactivity and HPLC-fingerprint in a common garden experiment.  INDUSTRIAL CROPS AND PRODUCTS,  134  (225).  [PMID:] [10.1016/j.indcrop.2019.04.017]
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24. Xiaomin Xia, Bin Lu, Wenjing Dong, Bingwei Yang, Yawen Wang, Qi Qin, Zixuan Liu, Erqun Song, Yang Song.  (2018)  Atypical Gasdermin D and Mixed Lineage Kinase Domain-like Protein Leakage Aggravates Tetrachlorobenzoquinone-Induced Nod-like Receptor Protein 3 Inflammasome Activation.  CHEMICAL RESEARCH IN TOXICOLOGY,  31  (12): (1418–1425).  [PMID:30378427] [10.1021/acs.chemrestox.8b00306]
25. Zixuan Liu, Wenjing Dong, Bingwei Yang, Lu Peng, Xiaomin Xia, Lanxiang Pu, Na Zhang, Erqun Song, Yang Song.  (2018)  Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.  CHEMICAL RESEARCH IN TOXICOLOGY,  31  (11): (1230–1239).  [PMID:30358983] [10.1021/acs.chemrestox.8b00209]
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33. Xiufang Song, Qiong Shi, Zixuan Liu, Yawen Wang, Yuxin Wang, Erqun Song, Yang Song.  (2016)  Unpredicted Downregulation of RAD51 Suggests Genome Instability Induced by Tetrachlorobenzoquinone.  CHEMICAL RESEARCH IN TOXICOLOGY,  29  (12): (2184–2193).  [PMID:27989139] [10.1021/acs.chemrestox.6b00369]
34. Xiaoxue Wu, Shan Sun, Yuhui Wang, Jiali Zhu, Kai Jiang, Yumin Leng, Qinghai Shu, Hengwei Lin.  (2017)  A fluorescent carbon-dots-based mitochondria-targetable nanoprobe for peroxynitrite sensing in living cells.  BIOSENSORS & BIOELECTRONICS,  90  (501).  [PMID:27825883] [10.1016/j.bios.2016.10.060]
35. Lijia Sang, Meiding Yang, Huipeng Zhou, Xinan Huang, Cong Yu.  (2016)  A benzoperylene probe self-assembled on polyethyleneimine/manganese doped ZnS quantum dots: a new nanocomposite for bright and tunable white light emission.  RSC Advances,  (86): (83110-83116).  [PMID:] [10.1039/C6RA18465K]
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Solution Calculators