Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C184839-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $584.90 | |
C184839-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,717.90 |
Synonyms | Ampliactil | chlorpromazine | Clorpromazina | Chlordelazin | HL 5746 | NSC-226514 | Cromedazine | Fraction AB | 2-chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine | chlorpromethazine | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine | C |
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Specifications & Purity | Moligand™, ≥95% |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | ANTAGONIST, CHANNEL BLOCKER |
Mechanism of action | D2-like dopamine receptor antagonist |
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IUPAC Name | 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine |
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INCHI | InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 |
InChi Key | ZPEIMTDSQAKGNT-UHFFFAOYSA-N |
Canonical SMILES | CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl |
Isomeric SMILES | CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl |
PubChem CID | 2726 |
Molecular Weight | 318.9 |
PubChem CID | 2726 |
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DrugBank Ligand | DB00477 |
CAS Registry No. | 50-53-3 |
ChEBI | CHEBI:3647 |
Wikipedia | Chlorpromazine |
ChEMBL Ligand | CHEMBL71 |
BindingDB Ligand | 50001888 |
NURSA Ligand | 10.1621/KVEDIV62XD |
RCSB PDB Ligand | Z80 |
PEP | chlorpromazine |
Reactome Reaction | R-HSA-9681616 |
Reactome Drug | R-ALL-9648300 |
DrugCentral Ligand | 621 |
GPCRdb Ligand | chlorpromazine |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B2426182 | Certificate of Analysis | Jan 25, 2024 | C184839 |
B2426184 | Certificate of Analysis | Jan 25, 2024 | C184839 |
B2426186 | Certificate of Analysis | Jan 25, 2024 | C184839 |
B2426188 | Certificate of Analysis | Jan 25, 2024 | C184839 |
F1829010 | Certificate of Analysis | Jan 04, 2024 | C184839 |
K2315064 | Certificate of Analysis | Nov 21, 2023 | C184839 |
F23051228 | Certificate of Analysis | Jun 12, 2023 | C184839 |
K2211350 | Certificate of Analysis | Nov 22, 2022 | C184839 |
Pictogram(s) | GHS06, GHS09, GHS07 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H331:Toxic if inhaled H317:May cause an allergic skin reaction H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects H362:May cause harm to breast-fed children |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P316:Get emergency medical help immediately. |
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27. Hou Zhenyu, Zhou Mei, Ma Yuanyuan, Xu Xiaoxuan, Zhang Zhiqi, Lai Shiwei, Fan Wenpei, Xie Jinbing, Ju Shenghong. (2022) Size-changeable nanoprobes for the combined radiotherapy and photodynamic therapy of tumor. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 49 (8): (2655-2667). [PMID:35536421] |
28. Peng Hua, Donglin Yang, Ruie Chen, Peiqi Qiu, Meiwan Chen. (2022) ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity. Bosnian Journal of Basic Medical Sciences, 22 (4): ( 593–607). [PMID:35531984] |
29. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di. (2022) Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment. COLLOIDS AND SURFACES B-BIOINTERFACES, 215 (112505). [PMID:35487070] |
30. Yu Zou, Quan Zhou, Yinan Zhao, Defu Zhi, Huiying Chen, Rui Wang, Benzhi Ju, Shubiao Zhang. (2022) Structure–activity relationships of pH-responsive and ionizable lipids for gene delivery. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 617 (121596). [PMID:35181463] |
31. Lijuan Yang, Shaochi Liu, Tian Quan, Yongqing Tao, Meng Tian, Luchun Wang, Junji Wang, Dandan Wang, Die Gao. (2022) Sulfuric-acid-mediated synthesis strategy for multi-colour aggregation-induced emission fluorescent carbon dots: Application in anti-counterfeiting, information encryption, and rapid cytoplasmic imaging. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 612 (650). [PMID:35030344] |
32. Zhuxian Wang, Yaqi Xue, Quanfu Zeng, Zhaoming Zhu, Yuan Wang, Yufan Wu, Chunyan Shen, Hongxia Zhu, Cuiping Jiang, Li Liu, Qiang Liu. (2022) Glycyrrhiza acid-Licochalcone A complexes for enhanced bioavailability and anti-melanogenic effect of Licochalcone A: cellular uptake and in vitro experiments. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 68 (103037). [PMID:] |
33. Li Wu, Yan Shi, Zihui Ni, Tao Yu, Zhipeng Chen. (2022) Preparation of a Self-Assembled Rhein–Doxorubicin Nanogel Targeting Mitochondria and Investigation on Its Antihepatoma Activity. MOLECULAR PHARMACEUTICS, 19 (1): (35–50). [PMID:34890210] |
34. Suleixin Yang, Ka Hong Wong, Peng Hua, Chengwei He, Hua Yu, Dan Shao, Zhi Shi, Meiwan Chen. (2022) ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy. Acta Biomaterialia, 140 (492). [PMID:34879292] |
35. Kambere Amerigos Daddy J C,Minglei Chen,Faisal Raza,Yanyu Xiao,Zhigui Su,Qineng Ping. (2020-02-28) Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia.. Pharmaceutics, 12 ((2)): [PMID:32102214] |
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