Chlorpromazine - 95%, high purity , D2-like dopamine receptor antagonist, CAS No.50-53-3, D2-like dopamine receptor antagonist

Item Number
C184839
Grouped product items
SKUSizeAvailabilityPrice Qty
C184839-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$584.90
C184839-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,717.90

Basic Description

SynonymsAmpliactil | chlorpromazine | Clorpromazina | Chlordelazin | HL 5746 | NSC-226514 | Cromedazine | Fraction AB | 2-chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine | chlorpromethazine | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine | C
Specifications & PurityMoligand™, ≥95%
Shipped InNormal
GradeMoligand™
Action TypeANTAGONIST, CHANNEL BLOCKER
Mechanism of actionD2-like dopamine receptor antagonist

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2D6 Tclin Cytochrome P450 2D6 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD1 Tclin D(1A) dopamine receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD2 Tclin D(2) dopamine receptor (14 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD4 Tchem D(4) dopamine receptor (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABCB1 Tchem Multidrug resistance protein 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH1 Tclin Histamine H1 receptor (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TRPC5 Tchem Short transient receptor potential channel 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A2 Tclin Sodium-dependent noradrenaline transporter (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A4 Tclin Sodium-dependent serotonin transporter (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD3 Tclin D(3) dopamine receptor (12 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD5 Tchem D(1B) dopamine receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2B Tclin Alpha-2B adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2C Tclin Alpha-2C adrenergic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (8 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR7 Tclin 5-hydroxytryptamine receptor 7 (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2A Tclin Alpha-2A adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1D Tclin Alpha-1D adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AOX1 Tchem Aldehyde oxidase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2C Tclin 5-hydroxytryptamine receptor 2C (6 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR6 Tchem 5-hydroxytryptamine receptor 6 (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNK2 Tclin Potassium channel subfamily K member 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (10 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRHR1 Tclin Corticotropin releasing factor receptor 1 (2996 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCGR Tclin Glucagon receptor (2563 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

TPR Trypanothione reductase (189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Htr7 Serotonin 7 (5-HT7) receptor (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ntsr1 Neurotensin receptor 1 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bdkrb1 Bradykinin B1 receptor (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nr1i3 Constitutive androstane receptor (427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium avium (4587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pneumocystis carinii (749 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycolicibacterium smegmatis (8003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania infantum (5912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei (78846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptosporidium parvum (1150 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania amazonensis (3813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania mexicana (936 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Toxoplasma gondii (4585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Felis catus (3858 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gerbillinae (442 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sindbis virus (1599 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium yoelii nigeriensis (1119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei rhodesiense (7991 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ScN2a (522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATP-ase (121 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Squirrel monkey (98 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
INCHI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
InChi Key ZPEIMTDSQAKGNT-UHFFFAOYSA-N
Canonical SMILES CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
Isomeric SMILES CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
PubChem CID 2726
Molecular Weight 318.9

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
B2426182Certificate of AnalysisJan 25, 2024 C184839
B2426184Certificate of AnalysisJan 25, 2024 C184839
B2426186Certificate of AnalysisJan 25, 2024 C184839
B2426188Certificate of AnalysisJan 25, 2024 C184839
F1829010Certificate of AnalysisJan 04, 2024 C184839
K2315064Certificate of AnalysisNov 21, 2023 C184839
F23051228Certificate of AnalysisJun 12, 2023 C184839
K2211350Certificate of AnalysisNov 22, 2022 C184839

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS09,   GHS07
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H331:Toxic if inhaled

H317:May cause an allergic skin reaction

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

H362:May cause harm to breast-fed children

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P263:Avoid contact during pregnancy/while nursing.

P203:Obtain, read and follow all safety instructions before use.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

P316:Get emergency medical help immediately.

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10. Wenjing Huang, Li Wang, Hao Zhang, Zhihao Han, Yueqing Gu.  (2023)  Near-infrared targeted EGFR fluorescent probe for tumor imaging and diagnosis.  SENSORS AND ACTUATORS B-CHEMICAL,  393  (134102).  [PMID:] [10.1016/j.snb.2023.134102]
11. Ping Guan, Zhaoxu Meng, Xinran Liu, Jiaxiang Mu, Zichun Gao, Xinrong Yu, He Lian.  (2023)  A biomimetic mineralization nanosystem based on glycolysis-oxidative stress-autophagy regulation for the suppression of malignant tumor and lung metastasis.  CHEMICAL ENGINEERING JOURNAL,  468  (143730).  [PMID:] [10.1016/j.cej.2023.143730]
12. Shengnan Huang, Chengzhi Song, Jinxin Miao, Xiali Zhu, Yongyan Jia, Yafei Liu, Dongjun Fu, Benyi Li, Mingsan Miao, Shaofeng Duan, Zhenzhong Zhang, Yurong Hu.  (2023)  Red blood cell membrane-coated functionalized Au nanocage as a biomimetic platform for improved MicroRNA delivery in hepatocellular carcinoma.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  642  (123044).  [PMID:37178790] [10.1016/j.ijpharm.2023.123044]
13. Xuan Nie, Wei You, Ze Zhang, Fan Gao, Xiao-Hong Zhou, Hai-Li Wang, Long-Hai Wang, Guang Chen, Chang-Hui Wang, Chun-Yan Hong, Qi Shao, Fei Wang, Lei Xia, Yang Li, Ye-Zi You.  (2023)  DPA-Zinc around Polyplexes Acts Like PEG to Reduce Protein Binding While Targeting Cancer Cells.  Advanced Healthcare Materials,  12  (21): (2203252).  [PMID:37154112] [10.1002/adhm.202203252]
14. Xin Chang, Chang Liu, Yu-Mo Han, Qiu-Ling Li, Bin Guo, Hu-Lin Jiang.  (2023)  Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion.  Molecular Therapy-Nucleic Acids,  32  (415-431).  [PMID:37159604] [10.1016/j.omtn.2023.04.006]
15. Yajing Wang, Ziwei Ding, Shiqun Lv, Jie Liu, Jie Pan, Yingcong Yu, Jun Gao, Xianfeng Huang.  (2023)  Development of tLyP-1 functionalized nanoliposomes with tunable internal water phase for glioma targeting.  JOURNAL OF LIPOSOME RESEARCH,      [PMID:36974836] [10.1080/08982104.2023.2191718]
16. Cen Chen, Yuhang Zhang, Yulong Tang, Guangrong Huang, Han Jiang.  (2023)  Preparation of magnetic molecularly imprinted polymers for selective extraction of xylazine in milk.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  58  (5): (2599-2608).  [PMID:] [10.1111/ijfs.16410]
17. Junwu Wei, Yuan Liu, Yingxin Li, Zhanlin Zhang, Jie Meng, Shuang Xie, Xiaohong Li.  (2023)  Photothermal Propelling and Pyroelectric Potential-Promoted Cell Internalization of Janus Nanoparticles and Pyroelectrodynamic Tumor Therapy.  Advanced Healthcare Materials,  12  (18): (2300338).  [PMID:36857737] [10.1002/adhm.202300338]
18. Yanzhi Xing, Yulong Xu, Yanna Lin, E Shuang, Han Leng, Jianhua Wang, Xuwei Chen.  (2023)  Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  640  (626).  [PMID:36889060] [10.1016/j.jcis.2023.02.133]
19. Han Haobo, Xing Jiakai, Chen Wenqi, Jia Jiaxin, Li Quanshun.  (2023)  Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats.  Nature Communications,  14  (1): (1-20).  [PMID:36805456] [10.1038/s41467-023-36625-7]
20. Wen-Juan Shen, Duo-Mei Tian, Le Fu, Biao Jin, Yu Liu, Yun-Sheng Xu, Yong-Bin Ye, Xiao-Bo Wang, Xiao-Jun Xu, Chun Tang, Fang-Ping Li, Chun-Fei Wang, Gang Wu, Le-Ping Yan.  (2023)  Elastin-Derived VGVAPG Fragment Decorated Cell-Penetrating Peptide with Improved Gene Delivery Efficacy.  Pharmaceutics,  15  (2): (670).  [PMID:36839992] [10.3390/pharmaceutics15020670]
21. Nini Xin, Dong Gao, Borui Su, Ting Zhou, Yuda Zhu, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan.  (2023)  Orange-Emissive Carbon Dots with High Photostability for Mitochondrial Dynamics Tracking in Living Cells.  ACS Sensors,  (3): (1161–1172).  [PMID:36795996] [10.1021/acssensors.2c02451]
22. Zhanlin Zhang, Tian Xia, Pan Ran, Junwu Wei, Jie Meng, Guiyuan Zhang, Xiaohong Li.  (2023)  Persistent luminescence-activated Janus nanomotors with integration of photodynamic and photothermal cancer therapies.  CHEMICAL ENGINEERING JOURNAL,  457  (141226).  [PMID:] [10.1016/j.cej.2022.141226]
23. Li Fangyuan, Sun Heng, Ren Jiafeng, Zhang Bo, Hu Xi, Fang Chunyan, Lee Jiyoung, Gu Hongzhou, Ling Daishun.  (2022)  A nuclease-mimetic platinum nanozyme induces concurrent DNA platination and oxidative cleavage to overcome cancer drug resistance.  Nature Communications,  13  (1): (1-16).  [PMID:36450764] [10.1038/s41467-022-35022-w]
24. Qianqian Han, Tongtong Zhang, Meifang Wang, Fei Yan, Jiyang Liu.  (2022)  Disposable Electrochemical Sensors for Highly Sensitive Detection of Chlorpromazine in Human Whole Blood Based on the Silica Nanochannel Array Modified Screen-Printed Carbon Electrode.  MOLECULES,  27  (23): (8200).  [PMID:36500293] [10.3390/molecules27238200]
25. Jie Yang, Xiuhua Pan, Jun Zhang, Siyu Ma, Jianeng Zhou, Zengguang Jia, Yawen Wei, Zengyi Liu, Ning Yang, Qi Shen.  (2022)  Reprogramming dysfunctional dendritic cells by a versatile metabolism nano-intervenor for enhancing cancer combinatorial immunotherapy.  Nano Today,  46  (101618).  [PMID:] [10.1016/j.nantod.2022.101618]
26. Yongtao You, Silan Bai, Yamin Ma, Cheng Liu, Lishi Wang.  (2022)  A Nanopipette Supported Oil/Water Interface Sensor for the Kinetics Analysis and Determination of Phenothiazine Derivatives.  ELECTROCHIMICA ACTA,  423  (140568).  [PMID:] [10.1016/j.electacta.2022.140568]
27. Hou Zhenyu, Zhou Mei, Ma Yuanyuan, Xu Xiaoxuan, Zhang Zhiqi, Lai Shiwei, Fan Wenpei, Xie Jinbing, Ju Shenghong.  (2022)  Size-changeable nanoprobes for the combined radiotherapy and photodynamic therapy of tumor.  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING,  49  (8): (2655-2667).  [PMID:35536421] [10.1007/s00259-022-05830-9]
28. Peng Hua, Donglin Yang, Ruie Chen, Peiqi Qiu, Meiwan Chen.  (2022)  ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity.  Bosnian Journal of Basic Medical Sciences,  22  (4): ( 593–607).  [PMID:35531984] [10.17305/bjbms.2021.6704]
29. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di.  (2022)  Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,  215  (112505).  [PMID:35487070] [10.1016/j.colsurfb.2022.112505]
30. Yu Zou, Quan Zhou, Yinan Zhao, Defu Zhi, Huiying Chen, Rui Wang, Benzhi Ju, Shubiao Zhang.  (2022)  Structure–activity relationships of pH-responsive and ionizable lipids for gene delivery.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  617  (121596).  [PMID:35181463] [10.1016/j.ijpharm.2022.121596]
31. Lijuan Yang, Shaochi Liu, Tian Quan, Yongqing Tao, Meng Tian, Luchun Wang, Junji Wang, Dandan Wang, Die Gao.  (2022)  Sulfuric-acid-mediated synthesis strategy for multi-colour aggregation-induced emission fluorescent carbon dots: Application in anti-counterfeiting, information encryption, and rapid cytoplasmic imaging.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  612  (650).  [PMID:35030344] [10.1016/j.jcis.2022.01.004]
32. Zhuxian Wang, Yaqi Xue, Quanfu Zeng, Zhaoming Zhu, Yuan Wang, Yufan Wu, Chunyan Shen, Hongxia Zhu, Cuiping Jiang, Li Liu, Qiang Liu.  (2022)  Glycyrrhiza acid-Licochalcone A complexes for enhanced bioavailability and anti-melanogenic effect of Licochalcone A: cellular uptake and in vitro experiments.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,  68  (103037).  [PMID:] [10.1016/j.jddst.2021.103037]
33. Li Wu, Yan Shi, Zihui Ni, Tao Yu, Zhipeng Chen.  (2022)  Preparation of a Self-Assembled Rhein–Doxorubicin Nanogel Targeting Mitochondria and Investigation on Its Antihepatoma Activity.  MOLECULAR PHARMACEUTICS,  19  (1): (35–50).  [PMID:34890210] [10.1021/acs.molpharmaceut.1c00565]
34. Suleixin Yang, Ka Hong Wong, Peng Hua, Chengwei He, Hua Yu, Dan Shao, Zhi Shi, Meiwan Chen.  (2022)  ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy.  Acta Biomaterialia,  140  (492).  [PMID:34879292] [10.1016/j.actbio.2021.11.042]
35. Dan Wang, Wenkai Feng, Xiaowei Wang, Dongfang Lin, Xuelei Wang, Xiaoru Guo, Qingfang Miao, Jie Ma, Guimin Xia.  (2021)  Promoted antitumor therapy on pancreatic cancer by a novel recombinant human albumin-bound miriplatin nanoparticle.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,  167  (106000).  [PMID:34517105] [10.1016/j.ejps.2021.106000]
36. Yu Liu, Huan-Huan Wan, Duo-Mei Tian, Xiao-Jun Xu, Chang-Long Bi, Xiao-Yong Zhan, Bi-Hui Huang, Yun-Sheng Xu, Le-Ping Yan.  (2021)  Development and Characterization of High Efficacy Cell-Penetrating Peptide via Modulation of the Histidine and Arginine Ratio for Gene Therapy.  Materials,  14  (16): (4674).  [PMID:34443195] [10.3390/ma14164674]
37. Yu Zhang, Junxi Liu, Pengfei Dou, Zhijing Wu, Ziming Zheng, Xianglin Pan, Tao Zhou, Kaiping Wang.  (2021)  Oral absorption characteristics and mechanisms of a pectin-type polysaccharide from Smilax china L. across the intestinal epithelium.  CARBOHYDRATE POLYMERS,  270  (118383).  [PMID:34364625] [10.1016/j.carbpol.2021.118383]
38. Mengqin Gu, Li Jiang, Liying Hao, Junzhuo Lu, Zhenqi Liu, Zixue Lei, Yijun Li, Chengge Hua, Wei Li, Xiyu Li.  (2021)  A novel theranostic nanoplatform for imaging-guided chemo-photothermal therapy in oral squamous cell carcinoma.  Journal of Materials Chemistry B,  (30): (6006-6016).  [PMID:34282440] [10.1039/D1TB01136G]
39. Ziming Zheng, Xianglin Pan, Haoyu Wang, Zhijing Wu, Mitchell A. Sullivan, Yuxuan Liu, Junxi Liu, Kaiping Wang, Yu Zhang.  (2021)  Mechanism of Lentinan Intestinal Absorption: Clathrin-Mediated Endocytosis and Macropinocytosis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  69  (26): (7344–7352).  [PMID:34132531] [10.1021/acs.jafc.1c00349]
40. Lei Luo, Min Wang, Yuan Zhou, Dongliu Xiang, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang, Kemin Wang.  (2021)  Ratiometric Fluorescent DNA Nanostructure for Mitochondrial ATP Imaging in Living Cells Based on Hybridization Chain Reaction.  ANALYTICAL CHEMISTRY,  93  (17): (6715–6722).  [PMID:33887142] [10.1021/acs.analchem.1c00176]
41. Qiu-Ping Feng, Yu-Ting Zhu, Yi-Zhen Yuan, Wen-Jie Li, Hao-Han Yu, Meng-Yuan Hu, Su-Yun Xiang, Shu-Qin Yu.  (2021)  Oral administration co-delivery nanoparticles of docetaxel and bevacizumab for improving intestinal absorption and enhancing anticancer activity.  Materials Science & Engineering C-Materials for Biological Applications,  124  (112039).  [PMID:33947539] [10.1016/j.msec.2021.112039]
42. Meng-Xian Liu, Na Ding, Shuai Chen, Yong-Liang Yu, Jian-Hua Wang.  (2021)  One-Step Synthesis of Carbon Nanoparticles Capable of Long-Term Tracking Lipid Droplet for Real-Time Monitoring of Lipid Catabolism and Pharmacodynamic Evaluation of Lipid-Lowering Drugs.  ANALYTICAL CHEMISTRY,  93  (12): (5284–5290).  [PMID:33724008] [10.1021/acs.analchem.1c00337]
43. Yuping Wei, Caiying Zhang, Man Zhang, Qionghong Niu, Fengli Hui, Zi Liu, Xia Xu.  (2021)  Insight of Synergistic Effect between CPP and Cargo on the Facilitation Mechanisms of R7-PTX Translocation: Experiments and Molecular Simulations.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,  161  (105790).  [PMID:33689859] [10.1016/j.ejps.2021.105790]
44. Weng Qinjie, Sun Heng, Fang Chunyan, Xia Fan, Liao Hongwei, Lee Jiyoung, Wang Jincheng, Xie An, Ren Jiafeng, Guo Xia, Li Fangyuan, Yang Bo, Ling Daishun.  (2021)  Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics.  Nature Communications,  12  (1): (1-14).  [PMID:33664241] [10.1038/s41467-021-21714-2]
45. Dengshuai Wei, Yingjie Yu, Xingcai Zhang, Yongheng Wang, Hao Chen, Yao Zhao, Fuyi Wang, Guanghua Rong, Wenwen Wang, Xiang Kang, Jing Cai, Zehua Wang, Ji-Ye Yin, Muhammad Hanif, Yongbing Sun, Gaofeng Zha, Linxian Li, Guohui Nie, Haihua Xiao.  (2020)  Breaking the Intracellular Redox Balance with Diselenium Nanoparticles for Maximizing Chemotherapy Efficacy on Patient-Derived Xenograft Models.  ACS Nano,  14  (12): (16984–16996).  [PMID:33283501] [10.1021/acsnano.0c06190]
46. Rong Rao, Xuhan Liu, Yinghuan Li, Xi Tan, Hong Zhou, Xicheng Bai, Xiangliang Yang, Wei Liu.  (2021)  Bioinspired zwitterionic polyphosphoester modified porous silicon nanoparticles for efficient oral insulin delivery.  Biomaterials Science,  (3): (685-699).  [PMID:33330897] [10.1039/D0BM01772H]
47. Hu Gaowei, Miao Yingjie, Luo Xi, Chu Wenhui, Fu Yongqian.  (2020)  Identification of a novel cell-penetrating peptide derived from the capsid protein of chicken anemia virus and its application in gene delivery.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  104  (24): (10503-10513).  [PMID:33141296] [10.1007/s00253-020-10988-z]
48. Zhanlin Zhang, Hui Yan, Shang Li, Yuan Liu, Pan Ran, Weijia Chen, Xiaohong Li.  (2021)  Janus rod-like micromotors to promote the tumor accumulation and cell internalization of therapeutic agents.  CHEMICAL ENGINEERING JOURNAL,  404  (127073).  [PMID:] [10.1016/j.cej.2020.127073]
49. Xinyi Tan, Na Yin, Zixu Liu, Rong Sun, Jingxin Gou, Tian Yin, Yu Zhang, Haibing He, Xing Tang.  (2020)  Hydrophilic and Electroneutral Nanoparticles to Overcome Mucus Trapping and Enhance Oral Delivery of Insulin.  MOLECULAR PHARMACEUTICS,  17  (9): (3177–3191).  [PMID:32697099] [10.1021/acs.molpharmaceut.0c00223]
50. Le Feng, Xiao Xiao, Jing Liu, Junyan Wang, Nan Zhang, Tao Bing, Xiangjun Liu, Ziping Zhang, Dihua Shangguan.  (2020)  Immunomodulatory Effects of Lycium barbarum Polysaccharide Extract and Its Uptake Behaviors at the Cellular Level.  MOLECULES,  25  (6): (1351).  [PMID:32188121] [10.3390/molecules25061351]
51. E. Shuang, Quan-Xing Mao, Jian-Hua Wang, Xu-Wei Chen.  (2020)  Carbon dots with tunable dual emissions: from the mechanism to the specific imaging of endoplasmic reticulum polarity.  Nanoscale,  12  (12): (6852-6860).  [PMID:32186547] [10.1039/C9NR10982J]
52. Jian Wang, Yangyang Li, Shouyu Wang, Fei Liu.  (2020)  Dynamics of transmissible gastroenteritis virus internalization unraveled by single-virus tracking in live cells.  FASEB JOURNAL,  34  (3): (4653-4669).  [PMID:32017270] [10.1096/fj.201902455R]
53. Chen Xiaolong, Hu Cuihua, Zhang Yanan, Hao Wenjing, He Xu, Li Qing, Huang Yuxi, Huang Yibing, Chen Yuxin.  (2020)  Anticancer Activity and Mechanism of Action of kla-TAT Peptide.  International Journal of Peptide Research and Therapeutics,  26  (4): (2285-2296).  [PMID:] [10.1007/s10989-020-10019-5]
54. Siyu Guan, Qianqian Zhang, Jianwei Bao, Tijie Duan, Rongfeng Hu, Tori Czech, Jihui Tang.  (2020)  Phosphatidylserine targeting peptide-functionalized pH sensitive mixed micelles for enhanced anti-tumor drug delivery.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,  147  (87).  [PMID:31899369] [10.1016/j.ejpb.2019.12.012]
55. Yajun Liu, Rui Dai, Qiuyu Wei, Wenzhe Li, Guang Zhu, Hao Chi, Zhaoming Guo, Li Wang, Changhao Cui, Jianqiang Xu, Kun Ma.  (2019)  Dual-Functionalized Janus Mesoporous Silica Nanoparticles with Active Targeting and Charge Reversal for Synergistic Tumor-Targeting Therapy.  ACS Applied Materials & Interfaces,  11  (47): (44582–44592).  [PMID:31682097] [10.1021/acsami.9b15434]
56. Ruihao Yang, Mengmeng Hou, Ya Gao, Shiyu Lu, Lei Zhang, Zhigang Xu, Chang Ming Li, Yuejun Kang, Peng Xue.  (2019)  Biomineralization-inspired Crystallization of Manganese Oxide on Silk Fibroin Nanoparticles for in vivo MR/fluorescence Imaging-assisted Tri-modal Therapy of Cancer.  Theranostics,  (21): ( 6314–6333).  [PMID:31534553] [10.7150/thno.36252]
57. Tingting Luo, Jingtian Han, Feng Zhao, Xiaohong Pan, Baocheng Tian, Xiujuan Ding, Jing Zhang.  (2019)  Redox-sensitive micelles based on retinoic acid modified chitosan conjugate for intracellular drug delivery and smart drug release in cancer therapy.  CARBOHYDRATE POLYMERS,  215  (8).  [PMID:30981373] [10.1016/j.carbpol.2019.03.064]
58. Lipeng Qiu, Xiaotian Shan, Miaomiao Long, Kamel S. Ahmed, Li Zhao, Jing Mao, Huijie Zhang, Changling Sun, Chongzhao You, Guozhong Lv, Jinghua Chen.  (2019)  Elucidation of cellular uptake and intracellular trafficking of heparosan polysaccharide-based micelles in various cancer cells.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  130  (755).  [PMID:30851320] [10.1016/j.ijbiomac.2019.02.133]
59. Chunlai Feng, Haisheng Zhang, Jiaming Chen, Siqi Wang, Yuanrong Xin, Yang Qu, Qi Zhang, Wei Ji, Fumiyoshi Yamashita, Mengjie Rui, Ximing Xu.  (2019)  Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  560  (191).  [PMID:30769131] [10.1016/j.ijpharm.2019.02.009]
60. Shuang E, Quan-Xing Mao, Xiao-Li Yuan, Xiao-Lei Kong, Xu-Wei Chen, Jian-Hua Wang.  (2018)  Targeted imaging of the lysosome and endoplasmic reticulum and their pH monitoring with surface regulated carbon dots.  Nanoscale,  10  (26): (12788-12796).  [PMID:29947397] [10.1039/C8NR03453B]
61. Hu Gaowei, Zheng Wenlv, Li Ao, Mu Yaru, Shi Mingyu, Li Tuofan, Zou Haitao, Shao Hongxia, Qin Aijian, Ye Jianqiang.  (2018)  A novel CAV derived cell-penetrating peptide efficiently delivers exogenous molecules through caveolae-mediated endocytosis.  VETERINARY RESEARCH,  49  (1): (1-9).  [PMID:29439726] [10.1186/s13567-018-0513-2]
62. Yunti Zhang, Qimin Jiang, Bo Bi, Luming Xu, Jia Liu, Renxi Zhuo, Xulin Jiang.  (2018)  A bioreducible supramolecular nanoparticle gene delivery system based on cyclodextrin-conjugated polyaspartamide and adamantyl-terminated polyethylenimine.  Journal of Materials Chemistry B,  (5): (797-808).  [PMID:32254267] [10.1039/C7TB02170D]
63. Zhou Yang, Fan Wu, Hongjie Yang, Ping Zhou.  (2017)  Endocytosis mechanism of a novel proteoglycan, extracted from Ganoderma lucidum, in HepG2 cells.  RSC Advances,  (66): (41779-41786).  [PMID:] [10.1039/C7RA07520K]
64. Yue Yang, Xiaoyu Lu, Qi Liu, Yu Dai, Xiaojie Zhu, Yanli Wen, Jiaqiu Xu, Yang Lu, Di Zhao, Xijing Chen, Ning Li.  (2017)  Palmitoyl ascorbate and doxorubicin co-encapsulated liposome for synergistic anticancer therapy.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,  105  (219).  [PMID:28526602] [10.1016/j.ejps.2017.05.038]
65. Wenqi Chen, Yong Liu, Xiao Liang, Yu Huang, Quanshun Li.  (2017)  Chondroitin sulfate-functionalized polyamidoamine as a tumor-targeted carrier for miR-34a delivery.  Acta Biomaterialia,  57  (238).  [PMID:28511876] [10.1016/j.actbio.2017.05.030]
66. Xian Sun, Yingping Luo, Liwei Huang, Bo-Yang Yu, Jiangwei Tian.  (2017)  A peptide-decorated and curcumin-loaded mesoporous silica nanomedicine for effectively overcoming multidrug resistance in cancer cells.  RSC Advances,  (27): (16401-16409).  [PMID:] [10.1039/C7RA01128H]
67. Liu Di, Guo Hua, Zheng Wenyun, Zhang Na, Wang Tianwen, Wang Ping, Ma Xingyuan.  (2016)  Discovery of the cell-penetrating function of A2 domain derived from LTA subunit of Escherichia coli heat-labile enterotoxin.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  100  (11): (5079-5088).  [PMID:26960316] [10.1007/s00253-016-7423-x]
68. Zhen Xing, Sai Gao, Yan Duan, Haobo Han, Li Li, Yan Yang, Quanshun Li.  (2015)  Delivery of DNAzyme targeting aurora kinase A to inhibit the proliferation and migration of human prostate cancer.  International Journal of Nanomedicine,      [PMID:26425080] [10.2147/IJN.S90559]
69. Kambere Amerigos Daddy J C,Minglei Chen,Faisal Raza,Yanyu Xiao,Zhigui Su,Qineng Ping.  (2020-02-28)  Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia..  Pharmaceutics,  12  ((2)):   [PMID:32102214]

References

1. Xin Wang, Jinshuang Hu, Hua Wei, Zihan Li, Jian Liu, Jie Zhang, Shenghong Yang.  (2023)  Ultra-fast solvent-free protocol remodels the large-scale synthesis of carbon dots for nucleolus-targeting and white light-emitting diodes.  Journal of Colloid And Interface Science ,  649  (-): (785–794).  [PMID:] [https://doi.org/10.1016/j.jcis.2023.06.171]
2. Xucan Yang, Lulu Cheng, Yile Zhao, Haoran Ma, Haitao Song, Xuanmin Yang, Kang-Nan Wang, Yanrong Zhang.  (2024)  Aggregation-induced emission-active iridium (III)-based mitochondria-targeting nanoparticle for two-photon imaging-guided photodynamic therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  659  (320).  [PMID:38176241] [10.1016/j.jcis.2023.12.172]
3. Xin Yang, Wanqiong Li, Shuzhen Li, Shaomeng Chen, Zheng Hu, Zhuoying He, Xueqin Zhu, Xiaoshuang Niu, Xiuman Zhou, Huihao Li, Youmei Xiao, Juan Liu, Xinghua Sui, Guanyu Chen, Yanfeng Gao.  (2024)  Fish oil-based microemulsion can efficiently deliver oral peptide blocking PD-1/PD-L1 and simultaneously induce ferroptosis for cancer immunotherapy.  JOURNAL OF CONTROLLED RELEASE,  365  (654).  [PMID:38030081] [10.1016/j.jconrel.2023.11.042]
4. Shui Ling Yi, Zi Ling Li, Yan Chun Gong, Xiang Yuan Xiong.  (2023)  Inhibiting Multidrug Resistance with Transferrin-Targeted Polymersomes through Optimization of Ligand Density.  LANGMUIR,  39  (45): (15920–15931).  [PMID:37922445] [10.1021/acs.langmuir.3c01726]
5. Gongxi Qiao, Xuming Pan, Mengyun He, Ruixi Peng, Xiangrong Huang, Cunpeng Nie, Jianhui Jiang, Xia Chu.  (2023)  An ultrathin Zn-based layered double hydroxides augment degradation of mutant p53 to improve tumor therapy.  CHEMICAL ENGINEERING JOURNAL,  475  (13): (146449).  [PMID:27619977] [10.1016/j.cej.2023.146449]
6. Jianbo Li, Yaru Xu, Jieke Zhang, Qinglian Li, Chenxu Wang, Zhe Wu, Weijing Yang, Meng Xu, Zhenzhong Zhang, Lei Wang, Jinjie Zhang.  (2023)  Bioinspired fine-tuning of the mechanical rigidity of SNEDDS for the efficient crossing of multiple gastrointestinal barriers.  JOURNAL OF CONTROLLED RELEASE,  362  (170).  [PMID:37625600] [10.1016/j.jconrel.2023.08.044]
7. Mingqiao Li, Hedan Xu, Nan Zhao, Liangjun Zhang, Haihan Xia, Xiaoxun Zhang, Qiao Li, Min Liao, Qiong Pan, Zeng Yi, Jin Chai.  (2023)  Hepatocyte-targeted hyaluronic acid-polyethyleneimine conjugates for acute liver injury therapy by ROS elimination and inflammation modulation.  MATERIALS & DESIGN,  233  (112212).  [PMID:] [10.1016/j.matdes.2023.112212]
8. Zhanlin Zhang, Hui Yan, Wenxiong Cao, Shuang Xie, Pan Ran, Kun Wei, Xiaohong Li.  (2023)  Ultrasound-Chargeable Persistent Luminescence Nanoparticles to Generate Self-Propelled Motion and Photothermal/NO Therapy for Synergistic Tumor Treatment.  ACS Nano,      [PMID:37515593] [10.1021/acsnano.3c04906]
9. Peifu Xiao, Xiaoguang Tao, Hanxun Wang, Hongbing Liu, Yupeng Feng, Yueqi Zhu, Zhengzhen Jiang, Tian Yin, Yu Zhang, Haibing He, Jingxin Gou, Xing Tang.  (2023)  Enzyme/pH dual stimuli-responsive nanoplatform co-deliver disulfiram and doxorubicin for effective treatment of breast cancer lung metastasis.  Expert Opinion on Drug Delivery,  20  (7): (1015-1031).  [PMID:37452715] [10.1080/17425247.2023.2237888]
10. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu.  (2023)  Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  234  (115557).  [PMID:37406464] [10.1016/j.jpba.2023.115557]
11. Wenjing Huang, Li Wang, Hao Zhang, Zhihao Han, Yueqing Gu.  (2023)  Near-infrared targeted EGFR fluorescent probe for tumor imaging and diagnosis.  SENSORS AND ACTUATORS B-CHEMICAL,  393  (134102).  [PMID:] [10.1016/j.snb.2023.134102]
12. Ping Guan, Zhaoxu Meng, Xinran Liu, Jiaxiang Mu, Zichun Gao, Xinrong Yu, He Lian.  (2023)  A biomimetic mineralization nanosystem based on glycolysis-oxidative stress-autophagy regulation for the suppression of malignant tumor and lung metastasis.  CHEMICAL ENGINEERING JOURNAL,  468  (143730).  [PMID:] [10.1016/j.cej.2023.143730]
13. Shengnan Huang, Chengzhi Song, Jinxin Miao, Xiali Zhu, Yongyan Jia, Yafei Liu, Dongjun Fu, Benyi Li, Mingsan Miao, Shaofeng Duan, Zhenzhong Zhang, Yurong Hu.  (2023)  Red blood cell membrane-coated functionalized Au nanocage as a biomimetic platform for improved MicroRNA delivery in hepatocellular carcinoma.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  642  (123044).  [PMID:37178790] [10.1016/j.ijpharm.2023.123044]
14. Xuan Nie, Wei You, Ze Zhang, Fan Gao, Xiao-Hong Zhou, Hai-Li Wang, Long-Hai Wang, Guang Chen, Chang-Hui Wang, Chun-Yan Hong, Qi Shao, Fei Wang, Lei Xia, Yang Li, Ye-Zi You.  (2023)  DPA-Zinc around Polyplexes Acts Like PEG to Reduce Protein Binding While Targeting Cancer Cells.  Advanced Healthcare Materials,  12  (21): (2203252).  [PMID:37154112] [10.1002/adhm.202203252]
15. Xin Chang, Chang Liu, Yu-Mo Han, Qiu-Ling Li, Bin Guo, Hu-Lin Jiang.  (2023)  Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion.  Molecular Therapy-Nucleic Acids,  32  (415-431).  [PMID:37159604] [10.1016/j.omtn.2023.04.006]
16. Yajing Wang, Ziwei Ding, Shiqun Lv, Jie Liu, Jie Pan, Yingcong Yu, Jun Gao, Xianfeng Huang.  (2023)  Development of tLyP-1 functionalized nanoliposomes with tunable internal water phase for glioma targeting.  JOURNAL OF LIPOSOME RESEARCH,      [PMID:36974836] [10.1080/08982104.2023.2191718]
17. Cen Chen, Yuhang Zhang, Yulong Tang, Guangrong Huang, Han Jiang.  (2023)  Preparation of magnetic molecularly imprinted polymers for selective extraction of xylazine in milk.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  58  (5): (2599-2608).  [PMID:] [10.1111/ijfs.16410]
18. Junwu Wei, Yuan Liu, Yingxin Li, Zhanlin Zhang, Jie Meng, Shuang Xie, Xiaohong Li.  (2023)  Photothermal Propelling and Pyroelectric Potential-Promoted Cell Internalization of Janus Nanoparticles and Pyroelectrodynamic Tumor Therapy.  Advanced Healthcare Materials,  12  (18): (2300338).  [PMID:36857737] [10.1002/adhm.202300338]
19. Yanzhi Xing, Yulong Xu, Yanna Lin, E Shuang, Han Leng, Jianhua Wang, Xuwei Chen.  (2023)  Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  640  (626).  [PMID:36889060] [10.1016/j.jcis.2023.02.133]
20. Han Haobo, Xing Jiakai, Chen Wenqi, Jia Jiaxin, Li Quanshun.  (2023)  Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats.  Nature Communications,  14  (1): (1-20).  [PMID:36805456] [10.1038/s41467-023-36625-7]
21. Wen-Juan Shen, Duo-Mei Tian, Le Fu, Biao Jin, Yu Liu, Yun-Sheng Xu, Yong-Bin Ye, Xiao-Bo Wang, Xiao-Jun Xu, Chun Tang, Fang-Ping Li, Chun-Fei Wang, Gang Wu, Le-Ping Yan.  (2023)  Elastin-Derived VGVAPG Fragment Decorated Cell-Penetrating Peptide with Improved Gene Delivery Efficacy.  Pharmaceutics,  15  (2): (670).  [PMID:36839992] [10.3390/pharmaceutics15020670]
22. Nini Xin, Dong Gao, Borui Su, Ting Zhou, Yuda Zhu, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan.  (2023)  Orange-Emissive Carbon Dots with High Photostability for Mitochondrial Dynamics Tracking in Living Cells.  ACS Sensors,  (3): (1161–1172).  [PMID:36795996] [10.1021/acssensors.2c02451]
23. Zhanlin Zhang, Tian Xia, Pan Ran, Junwu Wei, Jie Meng, Guiyuan Zhang, Xiaohong Li.  (2023)  Persistent luminescence-activated Janus nanomotors with integration of photodynamic and photothermal cancer therapies.  CHEMICAL ENGINEERING JOURNAL,  457  (141226).  [PMID:] [10.1016/j.cej.2022.141226]
24. Li Fangyuan, Sun Heng, Ren Jiafeng, Zhang Bo, Hu Xi, Fang Chunyan, Lee Jiyoung, Gu Hongzhou, Ling Daishun.  (2022)  A nuclease-mimetic platinum nanozyme induces concurrent DNA platination and oxidative cleavage to overcome cancer drug resistance.  Nature Communications,  13  (1): (1-16).  [PMID:36450764] [10.1038/s41467-022-35022-w]
25. Qianqian Han, Tongtong Zhang, Meifang Wang, Fei Yan, Jiyang Liu.  (2022)  Disposable Electrochemical Sensors for Highly Sensitive Detection of Chlorpromazine in Human Whole Blood Based on the Silica Nanochannel Array Modified Screen-Printed Carbon Electrode.  MOLECULES,  27  (23): (8200).  [PMID:36500293] [10.3390/molecules27238200]
26. Jie Yang, Xiuhua Pan, Jun Zhang, Siyu Ma, Jianeng Zhou, Zengguang Jia, Yawen Wei, Zengyi Liu, Ning Yang, Qi Shen.  (2022)  Reprogramming dysfunctional dendritic cells by a versatile metabolism nano-intervenor for enhancing cancer combinatorial immunotherapy.  Nano Today,  46  (101618).  [PMID:] [10.1016/j.nantod.2022.101618]
27. Yongtao You, Silan Bai, Yamin Ma, Cheng Liu, Lishi Wang.  (2022)  A Nanopipette Supported Oil/Water Interface Sensor for the Kinetics Analysis and Determination of Phenothiazine Derivatives.  ELECTROCHIMICA ACTA,  423  (140568).  [PMID:] [10.1016/j.electacta.2022.140568]
28. Hou Zhenyu, Zhou Mei, Ma Yuanyuan, Xu Xiaoxuan, Zhang Zhiqi, Lai Shiwei, Fan Wenpei, Xie Jinbing, Ju Shenghong.  (2022)  Size-changeable nanoprobes for the combined radiotherapy and photodynamic therapy of tumor.  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING,  49  (8): (2655-2667).  [PMID:35536421] [10.1007/s00259-022-05830-9]
29. Peng Hua, Donglin Yang, Ruie Chen, Peiqi Qiu, Meiwan Chen.  (2022)  ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity.  Bosnian Journal of Basic Medical Sciences,  22  (4): ( 593–607).  [PMID:35531984] [10.17305/bjbms.2021.6704]
30. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di.  (2022)  Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,  215  (112505).  [PMID:35487070] [10.1016/j.colsurfb.2022.112505]
31. Yu Zou, Quan Zhou, Yinan Zhao, Defu Zhi, Huiying Chen, Rui Wang, Benzhi Ju, Shubiao Zhang.  (2022)  Structure–activity relationships of pH-responsive and ionizable lipids for gene delivery.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  617  (121596).  [PMID:35181463] [10.1016/j.ijpharm.2022.121596]
32. Lijuan Yang, Shaochi Liu, Tian Quan, Yongqing Tao, Meng Tian, Luchun Wang, Junji Wang, Dandan Wang, Die Gao.  (2022)  Sulfuric-acid-mediated synthesis strategy for multi-colour aggregation-induced emission fluorescent carbon dots: Application in anti-counterfeiting, information encryption, and rapid cytoplasmic imaging.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  612  (650).  [PMID:35030344] [10.1016/j.jcis.2022.01.004]
33. Zhuxian Wang, Yaqi Xue, Quanfu Zeng, Zhaoming Zhu, Yuan Wang, Yufan Wu, Chunyan Shen, Hongxia Zhu, Cuiping Jiang, Li Liu, Qiang Liu.  (2022)  Glycyrrhiza acid-Licochalcone A complexes for enhanced bioavailability and anti-melanogenic effect of Licochalcone A: cellular uptake and in vitro experiments.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,  68  (103037).  [PMID:] [10.1016/j.jddst.2021.103037]
34. Li Wu, Yan Shi, Zihui Ni, Tao Yu, Zhipeng Chen.  (2022)  Preparation of a Self-Assembled Rhein–Doxorubicin Nanogel Targeting Mitochondria and Investigation on Its Antihepatoma Activity.  MOLECULAR PHARMACEUTICS,  19  (1): (35–50).  [PMID:34890210] [10.1021/acs.molpharmaceut.1c00565]
35. Suleixin Yang, Ka Hong Wong, Peng Hua, Chengwei He, Hua Yu, Dan Shao, Zhi Shi, Meiwan Chen.  (2022)  ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy.  Acta Biomaterialia,  140  (492).  [PMID:34879292] [10.1016/j.actbio.2021.11.042]
36. Dan Wang, Wenkai Feng, Xiaowei Wang, Dongfang Lin, Xuelei Wang, Xiaoru Guo, Qingfang Miao, Jie Ma, Guimin Xia.  (2021)  Promoted antitumor therapy on pancreatic cancer by a novel recombinant human albumin-bound miriplatin nanoparticle.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,  167  (106000).  [PMID:34517105] [10.1016/j.ejps.2021.106000]
37. Yu Liu, Huan-Huan Wan, Duo-Mei Tian, Xiao-Jun Xu, Chang-Long Bi, Xiao-Yong Zhan, Bi-Hui Huang, Yun-Sheng Xu, Le-Ping Yan.  (2021)  Development and Characterization of High Efficacy Cell-Penetrating Peptide via Modulation of the Histidine and Arginine Ratio for Gene Therapy.  Materials,  14  (16): (4674).  [PMID:34443195] [10.3390/ma14164674]
38. Yu Zhang, Junxi Liu, Pengfei Dou, Zhijing Wu, Ziming Zheng, Xianglin Pan, Tao Zhou, Kaiping Wang.  (2021)  Oral absorption characteristics and mechanisms of a pectin-type polysaccharide from Smilax china L. across the intestinal epithelium.  CARBOHYDRATE POLYMERS,  270  (118383).  [PMID:34364625] [10.1016/j.carbpol.2021.118383]
39. Mengqin Gu, Li Jiang, Liying Hao, Junzhuo Lu, Zhenqi Liu, Zixue Lei, Yijun Li, Chengge Hua, Wei Li, Xiyu Li.  (2021)  A novel theranostic nanoplatform for imaging-guided chemo-photothermal therapy in oral squamous cell carcinoma.  Journal of Materials Chemistry B,  (30): (6006-6016).  [PMID:34282440] [10.1039/D1TB01136G]
40. Ziming Zheng, Xianglin Pan, Haoyu Wang, Zhijing Wu, Mitchell A. Sullivan, Yuxuan Liu, Junxi Liu, Kaiping Wang, Yu Zhang.  (2021)  Mechanism of Lentinan Intestinal Absorption: Clathrin-Mediated Endocytosis and Macropinocytosis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  69  (26): (7344–7352).  [PMID:34132531] [10.1021/acs.jafc.1c00349]
41. Lei Luo, Min Wang, Yuan Zhou, Dongliu Xiang, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang, Kemin Wang.  (2021)  Ratiometric Fluorescent DNA Nanostructure for Mitochondrial ATP Imaging in Living Cells Based on Hybridization Chain Reaction.  ANALYTICAL CHEMISTRY,  93  (17): (6715–6722).  [PMID:33887142] [10.1021/acs.analchem.1c00176]
42. Qiu-Ping Feng, Yu-Ting Zhu, Yi-Zhen Yuan, Wen-Jie Li, Hao-Han Yu, Meng-Yuan Hu, Su-Yun Xiang, Shu-Qin Yu.  (2021)  Oral administration co-delivery nanoparticles of docetaxel and bevacizumab for improving intestinal absorption and enhancing anticancer activity.  Materials Science & Engineering C-Materials for Biological Applications,  124  (112039).  [PMID:33947539] [10.1016/j.msec.2021.112039]
43. Meng-Xian Liu, Na Ding, Shuai Chen, Yong-Liang Yu, Jian-Hua Wang.  (2021)  One-Step Synthesis of Carbon Nanoparticles Capable of Long-Term Tracking Lipid Droplet for Real-Time Monitoring of Lipid Catabolism and Pharmacodynamic Evaluation of Lipid-Lowering Drugs.  ANALYTICAL CHEMISTRY,  93  (12): (5284–5290).  [PMID:33724008] [10.1021/acs.analchem.1c00337]
44. Yuping Wei, Caiying Zhang, Man Zhang, Qionghong Niu, Fengli Hui, Zi Liu, Xia Xu.  (2021)  Insight of Synergistic Effect between CPP and Cargo on the Facilitation Mechanisms of R7-PTX Translocation: Experiments and Molecular Simulations.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,  161  (105790).  [PMID:33689859] [10.1016/j.ejps.2021.105790]
45. Weng Qinjie, Sun Heng, Fang Chunyan, Xia Fan, Liao Hongwei, Lee Jiyoung, Wang Jincheng, Xie An, Ren Jiafeng, Guo Xia, Li Fangyuan, Yang Bo, Ling Daishun.  (2021)  Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics.  Nature Communications,  12  (1): (1-14).  [PMID:33664241] [10.1038/s41467-021-21714-2]
46. Dengshuai Wei, Yingjie Yu, Xingcai Zhang, Yongheng Wang, Hao Chen, Yao Zhao, Fuyi Wang, Guanghua Rong, Wenwen Wang, Xiang Kang, Jing Cai, Zehua Wang, Ji-Ye Yin, Muhammad Hanif, Yongbing Sun, Gaofeng Zha, Linxian Li, Guohui Nie, Haihua Xiao.  (2020)  Breaking the Intracellular Redox Balance with Diselenium Nanoparticles for Maximizing Chemotherapy Efficacy on Patient-Derived Xenograft Models.  ACS Nano,  14  (12): (16984–16996).  [PMID:33283501] [10.1021/acsnano.0c06190]
47. Rong Rao, Xuhan Liu, Yinghuan Li, Xi Tan, Hong Zhou, Xicheng Bai, Xiangliang Yang, Wei Liu.  (2021)  Bioinspired zwitterionic polyphosphoester modified porous silicon nanoparticles for efficient oral insulin delivery.  Biomaterials Science,  (3): (685-699).  [PMID:33330897] [10.1039/D0BM01772H]
48. Hu Gaowei, Miao Yingjie, Luo Xi, Chu Wenhui, Fu Yongqian.  (2020)  Identification of a novel cell-penetrating peptide derived from the capsid protein of chicken anemia virus and its application in gene delivery.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  104  (24): (10503-10513).  [PMID:33141296] [10.1007/s00253-020-10988-z]
49. Zhanlin Zhang, Hui Yan, Shang Li, Yuan Liu, Pan Ran, Weijia Chen, Xiaohong Li.  (2021)  Janus rod-like micromotors to promote the tumor accumulation and cell internalization of therapeutic agents.  CHEMICAL ENGINEERING JOURNAL,  404  (127073).  [PMID:] [10.1016/j.cej.2020.127073]
50. Xinyi Tan, Na Yin, Zixu Liu, Rong Sun, Jingxin Gou, Tian Yin, Yu Zhang, Haibing He, Xing Tang.  (2020)  Hydrophilic and Electroneutral Nanoparticles to Overcome Mucus Trapping and Enhance Oral Delivery of Insulin.  MOLECULAR PHARMACEUTICS,  17  (9): (3177–3191).  [PMID:32697099] [10.1021/acs.molpharmaceut.0c00223]
51. Le Feng, Xiao Xiao, Jing Liu, Junyan Wang, Nan Zhang, Tao Bing, Xiangjun Liu, Ziping Zhang, Dihua Shangguan.  (2020)  Immunomodulatory Effects of Lycium barbarum Polysaccharide Extract and Its Uptake Behaviors at the Cellular Level.  MOLECULES,  25  (6): (1351).  [PMID:32188121] [10.3390/molecules25061351]
52. E. Shuang, Quan-Xing Mao, Jian-Hua Wang, Xu-Wei Chen.  (2020)  Carbon dots with tunable dual emissions: from the mechanism to the specific imaging of endoplasmic reticulum polarity.  Nanoscale,  12  (12): (6852-6860).  [PMID:32186547] [10.1039/C9NR10982J]
53. Jian Wang, Yangyang Li, Shouyu Wang, Fei Liu.  (2020)  Dynamics of transmissible gastroenteritis virus internalization unraveled by single-virus tracking in live cells.  FASEB JOURNAL,  34  (3): (4653-4669).  [PMID:32017270] [10.1096/fj.201902455R]
54. Chen Xiaolong, Hu Cuihua, Zhang Yanan, Hao Wenjing, He Xu, Li Qing, Huang Yuxi, Huang Yibing, Chen Yuxin.  (2020)  Anticancer Activity and Mechanism of Action of kla-TAT Peptide.  International Journal of Peptide Research and Therapeutics,  26  (4): (2285-2296).  [PMID:] [10.1007/s10989-020-10019-5]
55. Siyu Guan, Qianqian Zhang, Jianwei Bao, Tijie Duan, Rongfeng Hu, Tori Czech, Jihui Tang.  (2020)  Phosphatidylserine targeting peptide-functionalized pH sensitive mixed micelles for enhanced anti-tumor drug delivery.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,  147  (87).  [PMID:31899369] [10.1016/j.ejpb.2019.12.012]
56. Yajun Liu, Rui Dai, Qiuyu Wei, Wenzhe Li, Guang Zhu, Hao Chi, Zhaoming Guo, Li Wang, Changhao Cui, Jianqiang Xu, Kun Ma.  (2019)  Dual-Functionalized Janus Mesoporous Silica Nanoparticles with Active Targeting and Charge Reversal for Synergistic Tumor-Targeting Therapy.  ACS Applied Materials & Interfaces,  11  (47): (44582–44592).  [PMID:31682097] [10.1021/acsami.9b15434]
57. Ruihao Yang, Mengmeng Hou, Ya Gao, Shiyu Lu, Lei Zhang, Zhigang Xu, Chang Ming Li, Yuejun Kang, Peng Xue.  (2019)  Biomineralization-inspired Crystallization of Manganese Oxide on Silk Fibroin Nanoparticles for in vivo MR/fluorescence Imaging-assisted Tri-modal Therapy of Cancer.  Theranostics,  (21): ( 6314–6333).  [PMID:31534553] [10.7150/thno.36252]
58. Tingting Luo, Jingtian Han, Feng Zhao, Xiaohong Pan, Baocheng Tian, Xiujuan Ding, Jing Zhang.  (2019)  Redox-sensitive micelles based on retinoic acid modified chitosan conjugate for intracellular drug delivery and smart drug release in cancer therapy.  CARBOHYDRATE POLYMERS,  215  (8).  [PMID:30981373] [10.1016/j.carbpol.2019.03.064]
59. Lipeng Qiu, Xiaotian Shan, Miaomiao Long, Kamel S. Ahmed, Li Zhao, Jing Mao, Huijie Zhang, Changling Sun, Chongzhao You, Guozhong Lv, Jinghua Chen.  (2019)  Elucidation of cellular uptake and intracellular trafficking of heparosan polysaccharide-based micelles in various cancer cells.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  130  (755).  [PMID:30851320] [10.1016/j.ijbiomac.2019.02.133]
60. Chunlai Feng, Haisheng Zhang, Jiaming Chen, Siqi Wang, Yuanrong Xin, Yang Qu, Qi Zhang, Wei Ji, Fumiyoshi Yamashita, Mengjie Rui, Ximing Xu.  (2019)  Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  560  (191).  [PMID:30769131] [10.1016/j.ijpharm.2019.02.009]
61. Shuang E, Quan-Xing Mao, Xiao-Li Yuan, Xiao-Lei Kong, Xu-Wei Chen, Jian-Hua Wang.  (2018)  Targeted imaging of the lysosome and endoplasmic reticulum and their pH monitoring with surface regulated carbon dots.  Nanoscale,  10  (26): (12788-12796).  [PMID:29947397] [10.1039/C8NR03453B]
62. Hu Gaowei, Zheng Wenlv, Li Ao, Mu Yaru, Shi Mingyu, Li Tuofan, Zou Haitao, Shao Hongxia, Qin Aijian, Ye Jianqiang.  (2018)  A novel CAV derived cell-penetrating peptide efficiently delivers exogenous molecules through caveolae-mediated endocytosis.  VETERINARY RESEARCH,  49  (1): (1-9).  [PMID:29439726] [10.1186/s13567-018-0513-2]
63. Yunti Zhang, Qimin Jiang, Bo Bi, Luming Xu, Jia Liu, Renxi Zhuo, Xulin Jiang.  (2018)  A bioreducible supramolecular nanoparticle gene delivery system based on cyclodextrin-conjugated polyaspartamide and adamantyl-terminated polyethylenimine.  Journal of Materials Chemistry B,  (5): (797-808).  [PMID:32254267] [10.1039/C7TB02170D]
64. Zhou Yang, Fan Wu, Hongjie Yang, Ping Zhou.  (2017)  Endocytosis mechanism of a novel proteoglycan, extracted from Ganoderma lucidum, in HepG2 cells.  RSC Advances,  (66): (41779-41786).  [PMID:] [10.1039/C7RA07520K]
65. Yue Yang, Xiaoyu Lu, Qi Liu, Yu Dai, Xiaojie Zhu, Yanli Wen, Jiaqiu Xu, Yang Lu, Di Zhao, Xijing Chen, Ning Li.  (2017)  Palmitoyl ascorbate and doxorubicin co-encapsulated liposome for synergistic anticancer therapy.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,  105  (219).  [PMID:28526602] [10.1016/j.ejps.2017.05.038]
66. Wenqi Chen, Yong Liu, Xiao Liang, Yu Huang, Quanshun Li.  (2017)  Chondroitin sulfate-functionalized polyamidoamine as a tumor-targeted carrier for miR-34a delivery.  Acta Biomaterialia,  57  (238).  [PMID:28511876] [10.1016/j.actbio.2017.05.030]
67. Xian Sun, Yingping Luo, Liwei Huang, Bo-Yang Yu, Jiangwei Tian.  (2017)  A peptide-decorated and curcumin-loaded mesoporous silica nanomedicine for effectively overcoming multidrug resistance in cancer cells.  RSC Advances,  (27): (16401-16409).  [PMID:] [10.1039/C7RA01128H]
68. Liu Di, Guo Hua, Zheng Wenyun, Zhang Na, Wang Tianwen, Wang Ping, Ma Xingyuan.  (2016)  Discovery of the cell-penetrating function of A2 domain derived from LTA subunit of Escherichia coli heat-labile enterotoxin.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  100  (11): (5079-5088).  [PMID:26960316] [10.1007/s00253-016-7423-x]
69. Zhen Xing, Sai Gao, Yan Duan, Haobo Han, Li Li, Yan Yang, Quanshun Li.  (2015)  Delivery of DNAzyme targeting aurora kinase A to inhibit the proliferation and migration of human prostate cancer.  International Journal of Nanomedicine,      [PMID:26425080] [10.2147/IJN.S90559]
70. Kambere Amerigos Daddy J C,Minglei Chen,Faisal Raza,Yanyu Xiao,Zhigui Su,Qineng Ping.  (2020-02-28)  Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia..  Pharmaceutics,  12  ((2)):   [PMID:32102214]

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