Chlorpromazine - 95%, high purity , D2-like dopamine receptor antagonist, CAS No.50-53-3, D2-like dopamine receptor antagonist

35 Citations
Item Number
C184839
Grouped product items
SKUSizeAvailabilityPrice Qty
C184839-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$584.90
C184839-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,717.90

Basic Description

SynonymsAmpliactil | chlorpromazine | Clorpromazina | Chlordelazin | HL 5746 | NSC-226514 | Cromedazine | Fraction AB | 2-chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine | chlorpromethazine | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine | C
Specifications & PurityMoligand™, ≥95%
Shipped InNormal
GradeMoligand™
Action TypeANTAGONIST, CHANNEL BLOCKER
Mechanism of actionD2-like dopamine receptor antagonist

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2D6 Tclin Cytochrome P450 2D6 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD1 Tclin D(1A) dopamine receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD2 Tclin D(2) dopamine receptor (14 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD4 Tchem D(4) dopamine receptor (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABCB1 Tchem Multidrug resistance protein 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH1 Tclin Histamine H1 receptor (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TRPC5 Tchem Short transient receptor potential channel 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A2 Tclin Sodium-dependent noradrenaline transporter (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A4 Tclin Sodium-dependent serotonin transporter (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD3 Tclin D(3) dopamine receptor (12 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD5 Tchem D(1B) dopamine receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2B Tclin Alpha-2B adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2C Tclin Alpha-2C adrenergic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (8 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR7 Tclin 5-hydroxytryptamine receptor 7 (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2A Tclin Alpha-2A adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1D Tclin Alpha-1D adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AOX1 Tchem Aldehyde oxidase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2C Tclin 5-hydroxytryptamine receptor 2C (6 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR6 Tchem 5-hydroxytryptamine receptor 6 (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNK2 Tclin Potassium channel subfamily K member 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (10 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRHR1 Tclin Corticotropin releasing factor receptor 1 (2996 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCGR Tclin Glucagon receptor (2563 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

TPR Trypanothione reductase (189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Htr7 Serotonin 7 (5-HT7) receptor (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ntsr1 Neurotensin receptor 1 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bdkrb1 Bradykinin B1 receptor (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nr1i3 Constitutive androstane receptor (427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium avium (4587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pneumocystis carinii (749 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycolicibacterium smegmatis (8003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania infantum (5912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei (78846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptosporidium parvum (1150 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania amazonensis (3813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania mexicana (936 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Toxoplasma gondii (4585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Felis catus (3858 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gerbillinae (442 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sindbis virus (1599 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium yoelii nigeriensis (1119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei rhodesiense (7991 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ScN2a (522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATP-ase (121 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Squirrel monkey (98 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
INCHI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
InChi Key ZPEIMTDSQAKGNT-UHFFFAOYSA-N
Canonical SMILES CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
Isomeric SMILES CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
PubChem CID 2726
Molecular Weight 318.9

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
B2426182Certificate of AnalysisJan 25, 2024 C184839
B2426184Certificate of AnalysisJan 25, 2024 C184839
B2426186Certificate of AnalysisJan 25, 2024 C184839
B2426188Certificate of AnalysisJan 25, 2024 C184839
F1829010Certificate of AnalysisJan 04, 2024 C184839
K2315064Certificate of AnalysisNov 21, 2023 C184839
F23051228Certificate of AnalysisJun 12, 2023 C184839
K2211350Certificate of AnalysisNov 22, 2022 C184839

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS09,   GHS07
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H331:Toxic if inhaled

H317:May cause an allergic skin reaction

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

H362:May cause harm to breast-fed children

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P263:Avoid contact during pregnancy/while nursing.

P203:Obtain, read and follow all safety instructions before use.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

P316:Get emergency medical help immediately.

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12. Shengnan Huang, Chengzhi Song, Jinxin Miao, Xiali Zhu, Yongyan Jia, Yafei Liu, Dongjun Fu, Benyi Li, Mingsan Miao, Shaofeng Duan, Zhenzhong Zhang, Yurong Hu.  (2023)  Red blood cell membrane-coated functionalized Au nanocage as a biomimetic platform for improved MicroRNA delivery in hepatocellular carcinoma.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  642  (123044).  [PMID:37178790]
13. Xuan Nie, Wei You, Ze Zhang, Fan Gao, Xiao-Hong Zhou, Hai-Li Wang, Long-Hai Wang, Guang Chen, Chang-Hui Wang, Chun-Yan Hong, Qi Shao, Fei Wang, Lei Xia, Yang Li, Ye-Zi You.  (2023)  DPA-Zinc around Polyplexes Acts Like PEG to Reduce Protein Binding While Targeting Cancer Cells.  Advanced Healthcare Materials,  12  (21): (2203252).  [PMID:37154112]
14. Xin Chang, Chang Liu, Yu-Mo Han, Qiu-Ling Li, Bin Guo, Hu-Lin Jiang.  (2023)  Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion.  Molecular Therapy-Nucleic Acids,  32  (415-431).  [PMID:37159604]
15. Yajing Wang, Ziwei Ding, Shiqun Lv, Jie Liu, Jie Pan, Yingcong Yu, Jun Gao, Xianfeng Huang.  (2023)  Development of tLyP-1 functionalized nanoliposomes with tunable internal water phase for glioma targeting.  JOURNAL OF LIPOSOME RESEARCH,      [PMID:36974836]
16. Cen Chen, Yuhang Zhang, Yulong Tang, Guangrong Huang, Han Jiang.  (2023)  Preparation of magnetic molecularly imprinted polymers for selective extraction of xylazine in milk.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  58  (5): (2599-2608).  [PMID:]
17. Junwu Wei, Yuan Liu, Yingxin Li, Zhanlin Zhang, Jie Meng, Shuang Xie, Xiaohong Li.  (2023)  Photothermal Propelling and Pyroelectric Potential-Promoted Cell Internalization of Janus Nanoparticles and Pyroelectrodynamic Tumor Therapy.  Advanced Healthcare Materials,  12  (18): (2300338).  [PMID:36857737]
18. Yanzhi Xing, Yulong Xu, Yanna Lin, E Shuang, Han Leng, Jianhua Wang, Xuwei Chen.  (2023)  Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  640  (626).  [PMID:36889060]
19. Han Haobo, Xing Jiakai, Chen Wenqi, Jia Jiaxin, Li Quanshun.  (2023)  Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats.  Nature Communications,  14  (1): (1-20).  [PMID:36805456]
20. Wen-Juan Shen, Duo-Mei Tian, Le Fu, Biao Jin, Yu Liu, Yun-Sheng Xu, Yong-Bin Ye, Xiao-Bo Wang, Xiao-Jun Xu, Chun Tang, Fang-Ping Li, Chun-Fei Wang, Gang Wu, Le-Ping Yan.  (2023)  Elastin-Derived VGVAPG Fragment Decorated Cell-Penetrating Peptide with Improved Gene Delivery Efficacy.  Pharmaceutics,  15  (2): (670).  [PMID:36839992]
21. Nini Xin, Dong Gao, Borui Su, Ting Zhou, Yuda Zhu, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan.  (2023)  Orange-Emissive Carbon Dots with High Photostability for Mitochondrial Dynamics Tracking in Living Cells.  ACS Sensors,  (3): (1161–1172).  [PMID:36795996]
22. Zhanlin Zhang, Tian Xia, Pan Ran, Junwu Wei, Jie Meng, Guiyuan Zhang, Xiaohong Li.  (2023)  Persistent luminescence-activated Janus nanomotors with integration of photodynamic and photothermal cancer therapies.  CHEMICAL ENGINEERING JOURNAL,  457  (141226).  [PMID:]
23. Li Fangyuan, Sun Heng, Ren Jiafeng, Zhang Bo, Hu Xi, Fang Chunyan, Lee Jiyoung, Gu Hongzhou, Ling Daishun.  (2022)  A nuclease-mimetic platinum nanozyme induces concurrent DNA platination and oxidative cleavage to overcome cancer drug resistance.  Nature Communications,  13  (1): (1-16).  [PMID:36450764]
24. Qianqian Han, Tongtong Zhang, Meifang Wang, Fei Yan, Jiyang Liu.  (2022)  Disposable Electrochemical Sensors for Highly Sensitive Detection of Chlorpromazine in Human Whole Blood Based on the Silica Nanochannel Array Modified Screen-Printed Carbon Electrode.  MOLECULES,  27  (23): (8200).  [PMID:36500293]
25. Jie Yang, Xiuhua Pan, Jun Zhang, Siyu Ma, Jianeng Zhou, Zengguang Jia, Yawen Wei, Zengyi Liu, Ning Yang, Qi Shen.  (2022)  Reprogramming dysfunctional dendritic cells by a versatile metabolism nano-intervenor for enhancing cancer combinatorial immunotherapy.  Nano Today,  46  (101618).  [PMID:]
26. Yongtao You, Silan Bai, Yamin Ma, Cheng Liu, Lishi Wang.  (2022)  A Nanopipette Supported Oil/Water Interface Sensor for the Kinetics Analysis and Determination of Phenothiazine Derivatives.  ELECTROCHIMICA ACTA,  423  (140568).  [PMID:]
27. Hou Zhenyu, Zhou Mei, Ma Yuanyuan, Xu Xiaoxuan, Zhang Zhiqi, Lai Shiwei, Fan Wenpei, Xie Jinbing, Ju Shenghong.  (2022)  Size-changeable nanoprobes for the combined radiotherapy and photodynamic therapy of tumor.  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING,  49  (8): (2655-2667).  [PMID:35536421]
28. Peng Hua, Donglin Yang, Ruie Chen, Peiqi Qiu, Meiwan Chen.  (2022)  ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity.  Bosnian Journal of Basic Medical Sciences,  22  (4): ( 593–607).  [PMID:35531984]
29. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di.  (2022)  Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,  215  (112505).  [PMID:35487070]
30. Yu Zou, Quan Zhou, Yinan Zhao, Defu Zhi, Huiying Chen, Rui Wang, Benzhi Ju, Shubiao Zhang.  (2022)  Structure–activity relationships of pH-responsive and ionizable lipids for gene delivery.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  617  (121596).  [PMID:35181463]
31. Lijuan Yang, Shaochi Liu, Tian Quan, Yongqing Tao, Meng Tian, Luchun Wang, Junji Wang, Dandan Wang, Die Gao.  (2022)  Sulfuric-acid-mediated synthesis strategy for multi-colour aggregation-induced emission fluorescent carbon dots: Application in anti-counterfeiting, information encryption, and rapid cytoplasmic imaging.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  612  (650).  [PMID:35030344]
32. Zhuxian Wang, Yaqi Xue, Quanfu Zeng, Zhaoming Zhu, Yuan Wang, Yufan Wu, Chunyan Shen, Hongxia Zhu, Cuiping Jiang, Li Liu, Qiang Liu.  (2022)  Glycyrrhiza acid-Licochalcone A complexes for enhanced bioavailability and anti-melanogenic effect of Licochalcone A: cellular uptake and in vitro experiments.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,  68  (103037).  [PMID:]
33. Li Wu, Yan Shi, Zihui Ni, Tao Yu, Zhipeng Chen.  (2022)  Preparation of a Self-Assembled Rhein–Doxorubicin Nanogel Targeting Mitochondria and Investigation on Its Antihepatoma Activity.  MOLECULAR PHARMACEUTICS,  19  (1): (35–50).  [PMID:34890210]
34. Suleixin Yang, Ka Hong Wong, Peng Hua, Chengwei He, Hua Yu, Dan Shao, Zhi Shi, Meiwan Chen.  (2022)  ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy.  Acta Biomaterialia,  140  (492).  [PMID:34879292]
35. Kambere Amerigos Daddy J C,Minglei Chen,Faisal Raza,Yanyu Xiao,Zhigui Su,Qineng Ping.  (2020-02-28)  Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia..  Pharmaceutics,  12  ((2)):   [PMID:32102214]

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15. Xin Chang, Chang Liu, Yu-Mo Han, Qiu-Ling Li, Bin Guo, Hu-Lin Jiang.  (2023)  Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion.  Molecular Therapy-Nucleic Acids,  32  (415-431).  [PMID:37159604]
16. Yajing Wang, Ziwei Ding, Shiqun Lv, Jie Liu, Jie Pan, Yingcong Yu, Jun Gao, Xianfeng Huang.  (2023)  Development of tLyP-1 functionalized nanoliposomes with tunable internal water phase for glioma targeting.  JOURNAL OF LIPOSOME RESEARCH,      [PMID:36974836]
17. Cen Chen, Yuhang Zhang, Yulong Tang, Guangrong Huang, Han Jiang.  (2023)  Preparation of magnetic molecularly imprinted polymers for selective extraction of xylazine in milk.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  58  (5): (2599-2608).  [PMID:]
18. Junwu Wei, Yuan Liu, Yingxin Li, Zhanlin Zhang, Jie Meng, Shuang Xie, Xiaohong Li.  (2023)  Photothermal Propelling and Pyroelectric Potential-Promoted Cell Internalization of Janus Nanoparticles and Pyroelectrodynamic Tumor Therapy.  Advanced Healthcare Materials,  12  (18): (2300338).  [PMID:36857737]
19. Yanzhi Xing, Yulong Xu, Yanna Lin, E Shuang, Han Leng, Jianhua Wang, Xuwei Chen.  (2023)  Rational synthesis of carbon dots with phosphate ester group for direct mapping of endogenous alkaline phosphatase and polarity monitoring in living cells.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  640  (626).  [PMID:36889060]
20. Han Haobo, Xing Jiakai, Chen Wenqi, Jia Jiaxin, Li Quanshun.  (2023)  Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats.  Nature Communications,  14  (1): (1-20).  [PMID:36805456]
21. Wen-Juan Shen, Duo-Mei Tian, Le Fu, Biao Jin, Yu Liu, Yun-Sheng Xu, Yong-Bin Ye, Xiao-Bo Wang, Xiao-Jun Xu, Chun Tang, Fang-Ping Li, Chun-Fei Wang, Gang Wu, Le-Ping Yan.  (2023)  Elastin-Derived VGVAPG Fragment Decorated Cell-Penetrating Peptide with Improved Gene Delivery Efficacy.  Pharmaceutics,  15  (2): (670).  [PMID:36839992]
22. Nini Xin, Dong Gao, Borui Su, Ting Zhou, Yuda Zhu, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan.  (2023)  Orange-Emissive Carbon Dots with High Photostability for Mitochondrial Dynamics Tracking in Living Cells.  ACS Sensors,  (3): (1161–1172).  [PMID:36795996]
23. Zhanlin Zhang, Tian Xia, Pan Ran, Junwu Wei, Jie Meng, Guiyuan Zhang, Xiaohong Li.  (2023)  Persistent luminescence-activated Janus nanomotors with integration of photodynamic and photothermal cancer therapies.  CHEMICAL ENGINEERING JOURNAL,  457  (141226).  [PMID:]
24. Li Fangyuan, Sun Heng, Ren Jiafeng, Zhang Bo, Hu Xi, Fang Chunyan, Lee Jiyoung, Gu Hongzhou, Ling Daishun.  (2022)  A nuclease-mimetic platinum nanozyme induces concurrent DNA platination and oxidative cleavage to overcome cancer drug resistance.  Nature Communications,  13  (1): (1-16).  [PMID:36450764]
25. Qianqian Han, Tongtong Zhang, Meifang Wang, Fei Yan, Jiyang Liu.  (2022)  Disposable Electrochemical Sensors for Highly Sensitive Detection of Chlorpromazine in Human Whole Blood Based on the Silica Nanochannel Array Modified Screen-Printed Carbon Electrode.  MOLECULES,  27  (23): (8200).  [PMID:36500293]
26. Jie Yang, Xiuhua Pan, Jun Zhang, Siyu Ma, Jianeng Zhou, Zengguang Jia, Yawen Wei, Zengyi Liu, Ning Yang, Qi Shen.  (2022)  Reprogramming dysfunctional dendritic cells by a versatile metabolism nano-intervenor for enhancing cancer combinatorial immunotherapy.  Nano Today,  46  (101618).  [PMID:]
27. Yongtao You, Silan Bai, Yamin Ma, Cheng Liu, Lishi Wang.  (2022)  A Nanopipette Supported Oil/Water Interface Sensor for the Kinetics Analysis and Determination of Phenothiazine Derivatives.  ELECTROCHIMICA ACTA,  423  (140568).  [PMID:]
28. Hou Zhenyu, Zhou Mei, Ma Yuanyuan, Xu Xiaoxuan, Zhang Zhiqi, Lai Shiwei, Fan Wenpei, Xie Jinbing, Ju Shenghong.  (2022)  Size-changeable nanoprobes for the combined radiotherapy and photodynamic therapy of tumor.  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING,  49  (8): (2655-2667).  [PMID:35536421]
29. Peng Hua, Donglin Yang, Ruie Chen, Peiqi Qiu, Meiwan Chen.  (2022)  ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity.  Bosnian Journal of Basic Medical Sciences,  22  (4): ( 593–607).  [PMID:35531984]
30. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di.  (2022)  Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,  215  (112505).  [PMID:35487070]
31. Yu Zou, Quan Zhou, Yinan Zhao, Defu Zhi, Huiying Chen, Rui Wang, Benzhi Ju, Shubiao Zhang.  (2022)  Structure–activity relationships of pH-responsive and ionizable lipids for gene delivery.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  617  (121596).  [PMID:35181463]
32. Lijuan Yang, Shaochi Liu, Tian Quan, Yongqing Tao, Meng Tian, Luchun Wang, Junji Wang, Dandan Wang, Die Gao.  (2022)  Sulfuric-acid-mediated synthesis strategy for multi-colour aggregation-induced emission fluorescent carbon dots: Application in anti-counterfeiting, information encryption, and rapid cytoplasmic imaging.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  612  (650).  [PMID:35030344]
33. Zhuxian Wang, Yaqi Xue, Quanfu Zeng, Zhaoming Zhu, Yuan Wang, Yufan Wu, Chunyan Shen, Hongxia Zhu, Cuiping Jiang, Li Liu, Qiang Liu.  (2022)  Glycyrrhiza acid-Licochalcone A complexes for enhanced bioavailability and anti-melanogenic effect of Licochalcone A: cellular uptake and in vitro experiments.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,  68  (103037).  [PMID:]
34. Li Wu, Yan Shi, Zihui Ni, Tao Yu, Zhipeng Chen.  (2022)  Preparation of a Self-Assembled Rhein–Doxorubicin Nanogel Targeting Mitochondria and Investigation on Its Antihepatoma Activity.  MOLECULAR PHARMACEUTICS,  19  (1): (35–50).  [PMID:34890210]
35. Suleixin Yang, Ka Hong Wong, Peng Hua, Chengwei He, Hua Yu, Dan Shao, Zhi Shi, Meiwan Chen.  (2022)  ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy.  Acta Biomaterialia,  140  (492).  [PMID:34879292]
36. Kambere Amerigos Daddy J C,Minglei Chen,Faisal Raza,Yanyu Xiao,Zhigui Su,Qineng Ping.  (2020-02-28)  Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia..  Pharmaceutics,  12  ((2)):   [PMID:32102214]

Solution Calculators