Chlorprothixene - ≥98%, high purity , Serotonin 2c (5-HT2c) receptor antagonist, CAS No.113-59-7, Serotonin 2c (5-HT2c) receptor antagonist

Item Number

C129441

• Synonyms: Chlorprothixene 100 microg/mL in Acetonitrile | NCGC00166133-01 | CCG-36988 | Chlorprotixene | BRD-K81091703-003-01-0 | Clorprotisene | Clorprotixeno [INN-Spanish] | Ro 4-0403 | 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine | 9S7OD60EWP
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Potent, non-selective dopamine, 5-HT and H 1 receptor antagonist (K i values are 18, 3, 5, 9, 9, 3, 6 and 4 nM for D 1 , D 2 , D 3 , D5, 5-HT 2 , 5-HT 6 , 5-HT 7 and H 1 receptors respectively). α1-adrenoceptor and muscarinic receptor antagonist.
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: ANTAGONIST
• Mechanism of action: Serotonin 2c (5-HT2c) receptor antagonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.