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Cholecalciferol - meets USP testing specifications, high purity , CAS No.67-97-0

  • PharmPure™
  • USP
Item Number
C433298
Grouped product items
SKUSizeAvailabilityPrice Qty
C433298-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$101.90
C433298-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$252.90
C433298-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
C433298-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,190.90

Basic Description

SynonymsVitamin D3|cholecalciferol|67-97-0|Colecalciferol|Calciol|Ricketon|Oleovitamin D3|Deparal|Arachitol|Delsterol|Trivitan|Ebivit|Vigantol|Vigorsan|vitamin d-3|Colecalcipherol|Colecalciferolum|Cholecalciferolum|D3-Vicotrat|D3-Vigantol|Vi-de-3-hydrosol|NEO Doh
Specifications & PurityPharmPure™, USP
Biochemical and Physiological MechanismsVitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
GradePharmPure™, USP
Product Description

Cholecalciferol (vitamin D3), a fat-soluble steroid is produced in the skin.

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD4 Tchem D(4) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ELANE Tclin Neutrophil elastase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EGFR Tclin Epidermal growth factor receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDR Tclin Vascular endothelial growth factor receptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRNA7 Tchem Neuronal acetylcholine receptor subunit alpha-7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM4 Tclin Muscarinic acetylcholine receptor M4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AKR1B1 Tclin Aldose reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

F2 Tclin Prothrombin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EDNRA Tclin Endothelin-1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GLRA1 Tclin Glycine receptor subunit alpha-1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TACR1 Tclin Substance-P receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS1 Tchem Nitric oxide synthase, brain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
INCHI InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChi Key QYSXJUFSXHHAJI-YRZJJWOYSA-N
Canonical SMILES CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C
Isomeric SMILES C[C@H](CCCC(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C
WGK Germany 2
RTECS VS2900000
PubChem CID 5280795
UN Number 2811
Packing Group I
Molecular Weight 384.64
Beilstein 2339331

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
D2429174Certificate of AnalysisApr 19, 2024 C433298
D2429175Certificate of AnalysisApr 19, 2024 C433298
D2429176Certificate of AnalysisApr 19, 2024 C433298
D2429177Certificate of AnalysisApr 19, 2024 C433298
D2429178Certificate of AnalysisApr 19, 2024 C433298
D2429179Certificate of AnalysisApr 19, 2024 C433298
D2429180Certificate of AnalysisApr 19, 2024 C433298
D2429181Certificate of AnalysisApr 19, 2024 C433298

Chemical and Physical Properties

Specific Rotation[α]108 ° (C=0.5, EtOH)
Melt Point(°C)84-85°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08
Signal Danger
Hazard Statements

H300:Fatal if swallowed

H310:Fatal in contact with skin

H330:Fatal if inhaled

H372:Causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P330:Rinse mouth.

P262:Do not get in eyes, on skin, or on clothing.

P320:Specific treatment is urgent (see ... on this label).

P361+P364:Take off immediately all contaminated clothing and wash it before reuse.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS VS2900000
Class 6.1
Merck Index 10019

Related Documents

References

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28. Kanako Moriyama,Akiko Kukita,Yin-Ji Li,Norihisa Uehara,Jing-Qi Zhang,Ichiro Takahashi,Toshio Kukita.  (2014-09-30)  Regulation of osteoclastogenesis through Tim-3: possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction..  Laboratory investigation; a journal of technical methods and pathology,  94  ((11)): (1200-1211).  [PMID:25264706]
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32. Janna Nissen,Ulla Vogel,Gitte Ravn-Haren,Elisabeth W Andersen,Katja H Madsen,Bjørn A Nexø,Rikke Andersen,Heddie Mejborn,Poul J Bjerrum,Lone B Rasmussen,Hans Christian Wulf.  (2014-12-21)  Common variants in CYP2R1 and GC genes are both determinants of serum 25-hydroxyvitamin D concentrations after UVB irradiation and after consumption of vitamin D₃-fortified bread and milk during winter in Denmark..  The American journal of clinical nutrition,  101  ((1)): (218-227).  [PMID:25527766]
33. Joan Hui Juan Lim,Sharada Ravikumar,Yan-Ming Wang,Thomas Paulraj Thamboo,Lizhen Ong,Jinmiao Chen,Jessamine Geraldine Goh,Sen Hee Tay,Lufei Chengchen,Mar Soe Win,Winnie Leong,Titus Lau,Roger Foo,Haris Mirza,Kevin Shyong Wei Tan,Sunil Sethi,Ai Leng Khoo,Wee Joo Chng,Motomi Osato,Mihai G Netea,Yue Wang,Louis Yi Ann Chai.  (2015-01-24)  Bimodal Influence of Vitamin D in Host Response to Systemic Candida Infection-Vitamin D Dose Matters..  The Journal of infectious diseases,  212  ((4)): (635-644).  [PMID:25612733]
34. Melissa Jensen,Maisam Abu-El-Haija,Warren Bishop,Riad M Rahhal.  (2015-02-05)  Difficulty Achieving Vitamin D Sufficiency With High-Dose Oral Repletion Therapy in Infants With Cholestasis..  Journal of pediatric gastroenterology and nutrition,  61  ((2)): (187-189).  [PMID:25651487]
35. Isa Gabriela de Medeiros Cavalcante,Alexandre Sérgio Silva,Maria José Carvalho Costa,Darlene Camati Persuhn,Chahira Taha Mahd Ibrahim Issa,ChariraTahaMad Ibraim Issa,Tiago Lima de Luna Freire,Maria da Conceição Rodrigues Gonçalves.  (2015-04-02)  Effect of vitamin D3 supplementation and influence of BsmI polymorphism of the VDR gene of the inflammatory profile and oxidative stress in elderly women with vitamin D insufficiency: Vitamin D3 megadose reduces inflammatory markers..  Experimental gerontology,  66  (10-16).  [PMID:25827670]
36. Jamal S Lewis,Natalia V Dolgova,Ying Zhang,Chang Qing Xia,Clive H Wasserfall,Mark A Atkinson,Michael J Clare-Salzler,Benjamin G Keselowsky.  (2015-04-07)  A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice..  Clinical immunology (Orlando, Fla.),  160  ((1)): (90-102).  [PMID:25842187]
37. Mu-En Lin,Theodore Chen,Elizabeth M Leaf,Mei Y Speer,Cecilia M Giachelli.  (2015-05-20)  Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice..  The American journal of pathology,  185  ((7)): (1958-1969).  [PMID:25987250]
38. Dae-Jung Kang,Jong-Hyuk Im,Jae-Hoon Kang,Kyoung Heon Kim.  (2015-05-23)  Bioconversion of vitamin D3 to calcifediol by using resting cells of Pseudonocardia sp..  Biotechnology letters,  37  ((9)): (1895-1904).  [PMID:25994584]
39. Sonia Tabasum Ahmed,Md Manirul Islam,A B M Rubayet Bostami,Hong-Seok Mun,Ye-Jin Kim,Chul-Ju Yang.  (2015-06-05)  Meat composition, fatty acid profile and oxidative stability of meat from broilers supplemented with pomegranate (Punica granatum L.) by-products..  Food chemistry,  188  (481-488).  [PMID:26041221]
40. W P Weiss,E Azem,W Steinberg,T A Reinhardt.  (2015-06-09)  Effect of feeding 25-hydroxyvitamin D3 with a negative cation-anion difference diet on calcium and vitamin D status of periparturient cows and their calves..  Journal of dairy science,  98  ((8)): (5588-5600).  [PMID:26051311]
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Solution Calculators