cholest-5-ene-3,25-diol - >99%, high purity , CAS No.2140-46-7, Agonist of GPR183;Agonist of RAR-related orphan receptor-γ

Item Number

C130176

• Synonyms: 25-Hydroxycholesterol|2140-46-7|5-Cholestene-3beta,25-diol|25-OHC|Cholest-5-ene-3beta,25-diol|25-hydroxy-cholesterol|25-hydroxy cholesterol|cholest-5-en-3beta,25-diol|(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,
• Specifications & Purity: Moligand™, ≥99%
• Biochemical and Physiological Mechanisms: 25-Hydroxycholesterol is a side chain oxysterol that has been reported to trigger the activation of many cholesterol molecules. This triggers their movement from the cell membrane to the endoplasmic reticulum (ER). 25-Hydroxycholesterol affects the immune
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of GPR183;Agonist of RAR-related orphan receptor-γ
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Application：

25-Hydroxycholesterol was used to treat mouse neuroblastoma cells to activate the ABCA1 signaling and in studies related to fatty acid metabolism.