CI 988 - ≥99%(HPLC), high purity , Cholecystokinin B receptor antagonist, CAS No.130332-27-3, Cholecystokinin B receptor antagonist

Item Number

C288652

Grouped product items
SKU	Size	Availability	Price	Qty
C288652-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$304.90
C288652-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,201.90

Potent and selective CCK2antagonist

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Basic Description

Synonyms	UNII-2637PDX9SI \| BDBM50230678 \| GTPL873 \| CI988 \| CI-988 \| DTXSID701099873 \| PD-134308 \| CI 988 \| 2637PDX9SI \| CID 108187 \| SCHEMBL6895780 \| 2H-Isoindole-2-carboxylic acid,3-dihydro-1,3-dioxo-, ethyl ester \| BUTANOIC ACID, 4-(((1R)-2-(((2R)-3-(1H-INDOL-3
Specifications & Purity	Moligand™, ≥99%(HPLC)
Biochemical and Physiological Mechanisms	Potent and selective CCK2(CCK-B) receptor antagonist that displays ~ 1600-fold selectivity over CCK1receptors (IC50values are 1.7 and 2717 nM for CCK2and CCK1respectively). Has negligible affinity at a range of other binding sites (IC50> 10μM). Exhibits a
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Cholecystokinin B receptor antagonist

Associated Targets(Human)

CCKAR Tclin Cholecystokinin receptor type A (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCKBR Tclin Gastrin/cholecystokinin type B receptor (2 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	4-[[(1R)-2-[[(2R)-2-(2-adamantyloxycarbonylamino)-3-(1H-indol-3-yl)-2-methylpropanoyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid
INCHI	InChI=1S/C35H42N4O6/c1-35(18-26-19-36-28-10-6-5-9-27(26)28,39-34(44)45-32-24-14-21-13-22(16-24)17-25(32)15-21)33(43)37-20-29(23-7-3-2-4-8-23)38-30(40)11-12-31(41)42/h2-10,19,21-22,24-25,29,32,36H,11-18,20H2,1H3,(H,37,43)(H,38,40)(H,39,44)(H,41,42)/t21?,22?,24?,25?,29-,32?,35+/m0/s1
InChi Key	FVQSSYMRZKLFDR-ZABPBAJSSA-N
Canonical SMILES	CC(CC1=CNC2=CC=CC=C21)(C(=O)NCC(C3=CC=CC=C3)NC(=O)CCC(=O)O)NC(=O)OC4C5CC6CC(C5)CC4C6
Isomeric SMILES	C[C@@](CC1=CNC2=CC=CC=C21)(C(=O)NC[C@@H](C3=CC=CC=C3)NC(=O)CCC(=O)O)NC(=O)OC4C5CC6CC(C5)CC4C6
PubChem CID	108187
Molecular Weight	614.73