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Cibacron Blue 3G-A , CAS No.84166-13-2

Item Number
C274958
Grouped product items
SKUSizeAvailabilityPrice Qty
C274958-250mg
250mg
In stock
$54.90
C274958-1g
1g
In stock
$166.90
C274958-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$748.90

Anthraquinone derivative dye. Potent nucleotide-mimetic ligand

Basic Description

SynonymsCibacron Blue|84166-13-2|Cibacron Blue 3G-A|Cibacron blue 3GA|1-amino-4-[4-[[4-chloro-6-(2-sulfoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfoanilino]-9,10-dioxoanthracene-2-sulfonic acid|CHEMBL572528|GST Inhibitor-1 (Cibacron Blue 3G-A, Sodium Salt)|1-Amino-
Storage TempRoom temperature
Shipped InNormal
Product Description

product describtion:

Cibacron Blue 3G-A is an anionic anthraquinone dye. It is commonly used as a ligand in affinity chromatography for the purification of proteins, enzymes,Spectral properties and biopolymers.

Cibacron blue 3G-A has an absorbance maximum at 602 nm (in water).biopolymers.



Structure

Cibacron Blue 3G-A dye consists of anthraquinone backbond link to phenyl, triazine, and phenyl rings interconnected by C-N bonds and adorn by amine and sulfate functional moieties.


Application

Cibacron Blue 3G-A has been employed in the textile industry for many years. It has shown tremendous protein binding capacity and can readily be immobilized on the polymer containing a hydroxyl group. Due to its aforementioned properties, it has been used as a ligand in affinity chromatography for the purification of proteins and enzymes. It was also reported to apply for the purification of biopolymers (e.g., interferons and albumins).When immobilized using an insoluble porous support matrix such as agarose, Cibacron Blue 3GA is used for affinity chromatography purification of enzymes. This affinity has been attributed to a structural similarity between the dye and the natural ligands for proteins with cofactor binding domains.

Associated Targets

HPGDS Tchem Hematopoietic prostaglandin D synthase 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-amino-4-[4-[[4-chloro-6-(2-sulfoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfoanilino]-9,10-dioxoanthracene-2-sulfonic acid
INCHI InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-16-7-3-4-8-19(16)49(40,41)42)37-29(36-27)34-17-10-9-13(11-20(17)50(43,44)45)32-18-12-21(51(46,47)48)24(31)23-22(18)25(38)14-5-1-2-6-15(14)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)
InChi Key YKCWQPZFAFZLBI-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC(=C(C=C4)NC5=NC(=NC(=N5)NC6=CC=CC=C6S(=O)(=O)O)Cl)S(=O)(=O)O)S(=O)(=O)O)N
Isomeric SMILES C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC(=C(C=C4)NC5=NC(=NC(=N5)NC6=CC=CC=C6S(=O)(=O)O)Cl)S(=O)(=O)O)S(=O)(=O)O)N
WGK Germany 3
PubChem CID 172469
Molecular Weight 840.1

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
A2218406Certificate of AnalysisNov 14, 2022 C274958
A2218407Certificate of AnalysisNov 14, 2022 C274958
A2218408Certificate of AnalysisNov 14, 2022 C274958

Chemical and Physical Properties

SolubilitySoluble in Water to 10 mM
SensitivityLight sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

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