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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C274958-250mg | 250mg | In stock | $169.90 | |
C274958-1g | 1g | In stock | $459.90 | |
C274958-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,499.90 |
Anthraquinone derivative dye. Potent nucleotide-mimetic ligand
Synonyms | Cibacron Blue | MS-31403 | SCHEMBL4350042 | 2-Anthracenesulfonic acid, 1-amino-4-[[4-[[4-chloro-6-[(2-sulfophenyl)amino]-1,3,5-triazin-2-yl]amino]-3-sulfophenyl]amino]-9,10-dihydro-9,10-dioxo- | Q27093595 | 1-Amino-4-((4-((4-chloro-6-((2-sulfophenyl)amino |
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Biochemical and Physiological Mechanisms | Cibacron Blue 3GA is an anionized tantalum dye. It is a P2-niobium receptor antagonist and inhibits glutamate release of brain cortex tissue in rats that stimulates induction. Cibacron Blue 3GA inhibits OXA-1 and OXA-2 beta-lactamase and is used to monito |
Storage Temp | Room temperature |
Shipped In | Normal |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | product describtion: Cibacron Blue 3G-A is an anionic anthraquinone dye. It is commonly used as a ligand in affinity chromatography for the purification of proteins, enzymes,Spectral properties and biopolymers. Cibacron blue 3G-A has an absorbance maximum at 602 nm (in water).biopolymers. Structure Cibacron Blue 3G-A dye consists of anthraquinone backbond link to phenyl, triazine, and phenyl rings interconnected by C-N bonds and adorn by amine and sulfate functional moieties. Application Cibacron Blue 3G-A has been employed in the textile industry for many years. It has shown tremendous protein binding capacity and can readily be immobilized on the polymer containing a hydroxyl group. Due to its aforementioned properties, it has been used as a ligand in affinity chromatography for the purification of proteins and enzymes. It was also reported to apply for the purification of biopolymers (e.g., interferons and albumins).When immobilized using an insoluble porous support matrix such as agarose, Cibacron Blue 3GA is used for affinity chromatography purification of enzymes. This affinity has been attributed to a structural similarity between the dye and the natural ligands for proteins with cofactor binding domains. |
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IUPAC Name | 1-amino-4-[4-[[4-chloro-6-(2-sulfoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfoanilino]-9,10-dioxoanthracene-2-sulfonic acid |
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INCHI | InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-16-7-3-4-8-19(16)49(40,41)42)37-29(36-27)34-17-10-9-13(11-20(17)50(43,44)45)32-18-12-21(51(46,47)48)24(31)23-22(18)25(38)14-5-1-2-6-15(14)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37) |
InChi Key | YKCWQPZFAFZLBI-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC(=C(C=C4)NC5=NC(=NC(=N5)NC6=CC=CC=C6S(=O)(=O)O)Cl)S(=O)(=O)O)S(=O)(=O)O)N |
Isomeric SMILES | C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC(=C(C=C4)NC5=NC(=NC(=N5)NC6=CC=CC=C6S(=O)(=O)O)Cl)S(=O)(=O)O)S(=O)(=O)O)N |
WGK Germany | 3 |
Molecular Weight | 774.16 |
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Solubility | Soluble in Water to 10 mM |
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Sensitivity | Light sensitive |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Starting at $29.90