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Cinobufagin - 98%, high purity , CAS No.470-37-1
Basic Description Synonyms Cinobufagin | 470-37-1 | Cinobufagine | Cino-bufagin | T9PSN4R8IR | CHEBI:80805 | NSC90325 | NSC-90325 | [(1R,2S,4R,5R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-5-yl] acetate | UNII-T9PSN4R8IR | MFCD0 Specifications & Purity ≥98% Biochemical and Physiological Mechanisms Cinobufagin is a bufanolide steroid with anti-proliferative and pro-apoptotic effects as well as antinociception activity. It has been used in Chinese herbal medicine and has been shown to have clinical applications in a variety of cancers both as an anti Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Cinobufagin is a specific Na|+|/K|+|-ATPase inhibitor. About as active as ouabain.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name [(1R,2S,4R,5R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-5-yl] acetate INCHI InChI=1S/C26H34O6/c1-14(27)31-22-21(15-4-7-20(29)30-13-15)25(3)11-9-18-19(26(25)23(22)32-26)6-5-16-12-17(28)8-10-24(16,18)2/h4,7,13,16-19,21-23,28H,5-6,8-12H2,1-3H3/t16-,17+,18+,19-,21+,22-,23-,24+,25-,26-/m1/s1 InChi Key SCULJPGYOQQXTK-OLRINKBESA-N Canonical SMILES CC(=O)OC1C(C2(CCC3C(C24C1O4)CCC5C3(CCC(C5)O)C)C)C6=COC(=O)C=C6 Isomeric SMILES CC(=O)O[C@@H]1[C@@H]([C@]2(CC[C@H]3[C@H]([C@@]24[C@@H]1O4)CC[C@H]5[C@@]3(CC[C@@H](C5)O)C)C)C6=COC(=O)C=C6 WGK Germany 3 RTECS EI2955000 PubChem CID 11969542 Molecular Weight 442.54
Chemical and Physical Properties Solubility Soluble in chloroform, and water (partly). Sensitivity heat sensitive Refractive Index n20D1.60 (Predicted) Boil Point(°C) 595.42° C at 760 mmHg (Predicted) Melt Point(°C) ~211° C
Safety and Hazards(GHS) Pictogram(s) GHS06 Signal Danger Hazard Statements H300: Fatal if swallowed
H310: Fatal in contact with skin
H330: Fatal if inhaled
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P284: [In case of inadequate ventilation] Wear respiratory protection.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P330: Rinse mouth.
P262: Do not get in eyes, on skin, or on clothing.
P320: Specific treatment is urgent (see ... on this label).
P361+P364: Take off immediately all contaminated clothing and wash it before reuse.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P316: Get emergency medical help immediately.
WGK Germany 3 RTECS EI2955000
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