Clofarabine - 99%, high purity , CAS No.123318-82-1, Inhibitor of ribonucleotide reductase catalytic subunit M1;Inhibitor of ribonucleotide reductase regulatory subunit M2

Item Number

C102625

• Synonyms: Clofarabine | 123318-82-1 | Clolar | Evoltra | Clofarex | CAFdA | Cl-F-Ara-A | C1-F-Ara-A | clofarabina | clofarabinum | (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol | 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine |
• Specifications & Purity: Moligand™, ≥99%
• Biochemical and Physiological Mechanisms: Clofarabine is a purine nucleoside antimetabolite. Clofarabine is toxic to nondividing lymphocytes and monocytes.Antimetabolite agent. Purine analogue. Deoxycytidine kinase substrate. Competes with dATP for DNA polymerase-α and -ε. Potent ribonucleotide r
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of ribonucleotide reductase catalytic subunit M1;Inhibitor of ribonucleotide reductase regulatory subunit M2
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.