Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C123236-1g | 1g | In stock | $64.90 | |
C123236-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $366.90 | |
C123236-10g | 10g | In stock | $585.90 | |
C123236-25g | 25g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,316.90 |
Selective estrogen receptor modulator (SERM)
Synonyms | Clomifene citrate (Serophene) | Ethanamine, 2-(4-((1Z)-2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) | SW196898-3 | Z2235801947 | CS-0111663 | NSC-35770 | Triethylamine,2-diphenylvinyl)phenoxy]-, citrate | |
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Specifications & Purity | ≥98%, mixture of cis and trans |
Biochemical and Physiological Mechanisms | Selective estrogen receptor modulator (SERM) (IC 50 = 16 μM). Able to regulate apoptosis in tissue and cellular targets of estrogen signaling. Displays antiproliferative effects in vitro . Active in vivo . |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | A selective estrogen receptor modulator |
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IUPAC Name | 2-[4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid |
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INCHI | InChI=1S/C26H28ClNO.C6H8O7/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,3-4,19-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-; |
InChi Key | PYTMYKVIJXPNBD-OQKDUQJOSA-N |
Canonical SMILES | CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
Isomeric SMILES | CCN(CC)CCOC1=CC=C(C=C1)/C(=C(/C2=CC=CC=C2)\Cl)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
RTECS | YE0875000 |
PubChem CID | 3033832 |
Molecular Weight | 598.08 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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A2408121 | Certificate of Analysis | Nov 22, 2023 | C123236 |
A2408122 | Certificate of Analysis | Nov 22, 2023 | C123236 |
A2408123 | Certificate of Analysis | Nov 22, 2023 | C123236 |
I1417030 | Certificate of Analysis | Jul 11, 2022 | C123236 |
I1416031 | Certificate of Analysis | Jul 08, 2022 | C123236 |
Pictogram(s) | GHS08 |
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Signal | Warning |
Hazard Statements | H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
RTECS | YE0875000 |
1. Si L et al.. (2021) A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.. Nat Biomed Eng, 5 (8): (815-829). [PMID:33941899] |