Grouped product items

SKU

Size

Availability

Price

Qty

C127819-1mg

1mg

Available within 8-12 weeks(?)

$49.90

C127819-5mg

5mg

Available within 8-12 weeks(?)

$99.90

C127819-10mg

10mg

Available within 8-12 weeks(?)

$179.90

C127819-25mg

25mg

Available within 8-12 weeks(?)

$246.90

C127819-50mg

50mg

Available within 8-12 weeks(?)

$399.90

Basic Description

Synonyms	WHB79490 \| 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloroethan-1-one \| NCGC00485901-01 \| 1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone \| MS-25648 \| DTXSID10586567 \|
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	CMK is a RSK2 kinase inhibitor.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK.

Associated Targets(Human)

FYN Tclin Tyrosine-protein kinase FYN (5308 Activities)

Discover Target: FYN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

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BT-474 (2113 Activities)

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C8166 (1658 Activities)

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CA46 (271 Activities)

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Calu-6 (398 Activities)

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CCRF-CEM (65223 Activities)

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Daudi (625 Activities)

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DMS-79 (150 Activities)

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EVSA-T (142 Activities)

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HL-60 (67320 Activities)

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HuTu80 (255 Activities)

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IM-9 (160 Activities)

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JAR (316 Activities)

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JIYOYE (162 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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ML-2 (146 Activities)

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MOLT-4 (49676 Activities)

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NALM-6 (592 Activities)

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NCI-H128 (54 Activities)

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NCI-H345 (89 Activities)

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NTERA-2-cl-D1 (234 Activities)

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OVCAR-4 (44535 Activities)

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PSN1 (345 Activities)

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Raji (5516 Activities)

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RKO (1376 Activities)

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RPMI-8226 (44974 Activities)

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RXF 393 (41971 Activities)

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SCC-15 (194 Activities)

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SF-126 (160 Activities)

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SK-MEL-1 (285 Activities)

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SK-MEL-2 (46422 Activities)

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SNU1 (253 Activities)

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SNU-16 (476 Activities)

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SNU-5 (270 Activities)

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SUP-T1 (191 Activities)

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SW 954 (148 Activities)

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SW 962 (156 Activities)

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THP-1 (11052 Activities)

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TK-10 (45540 Activities)

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U-87 MG (3946 Activities)

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UACC-257 (46019 Activities)

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A253 cell line (154 Activities)

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A704 (149 Activities)

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RPMI 8402 (281 Activities)

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D283 Med (171 Activities)

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EKVX (44102 Activities)

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EOL1 (427 Activities)

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NCI-H322M (45589 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloroethanone
INCHI	InChI=1S/C18H19ClN4O2/c1-11-3-5-12(6-4-11)14-15-17(20)21-10-22-18(15)23(7-2-8-24)16(14)13(25)9-19/h3-6,10,24H,2,7-9H2,1H3,(H2,20,21,22)
InChi Key	PELFTNQHGSITLB-UHFFFAOYSA-N
Canonical SMILES	CC1=CC=C(C=C1)C2=C(N(C3=NC=NC(=C23)N)CCCO)C(=O)CCl
Isomeric SMILES	CC1=CC=C(C=C1)C2=C(N(C3=NC=NC(=C23)N)CCCO)C(=O)CCl
PubChem CID	16663089
Molecular Weight	358.83

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	DMSO

Solution Calculators

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CMK - ≥99%, high purity , CAS No.821794-90-5

Basic Description

Associated Targets(Human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
C127819-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$49.90
C127819-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$99.90
C127819-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$179.90
C127819-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$246.90
C127819-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$399.90