Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C131944-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $12.90 | |
C131944-5mg | 5mg | In stock | $48.90 | |
C131944-25mg | 25mg | In stock | $147.90 | |
C131944-100mg | 100mg | In stock | $375.90 |
AMPA / kainate antagonist
Synonyms | 6-cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione | BRD-K53545112-304-01-6 | EX-A5681 | GTPL5475 | 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE | [3H]CNQX | CNQX | CS-6970 | 6-Quinoxalinecarbonitrile,1,2,3,4-tetrahydro-7-nitro-2,3-dioxo- | Biomol-NT_000200 | BRD-K |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Potent, competitive AMPA/kainate glutamate receptor antagonist.Potent, competitive AMPA / kainate receptor antagonist. Also antagonist at NMDA receptor glycine site. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of GluA1;Antagonist of GluA2;GluA3;GluA4 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile |
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INCHI | InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15) |
InChi Key | RPXVIAFEQBNEAX-UHFFFAOYSA-N |
Canonical SMILES | C1=C(C(=CC2=C1NC(=O)C(=O)N2)[N+](=O)[O-])C#N |
Isomeric SMILES | C1=C(C(=CC2=C1NC(=O)C(=O)N2)[N+](=O)[O-])C#N |
WGK Germany | 3 |
Alternate CAS | 115066-14-3 |
PubChem CID | 3721046 |
MeSH Entry Terms | 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile;6 Cyano 2,3 dihydroxy 7 nitroquinoxaline;6 Cyano 7 nitroquinoxaline 2,3 dione;6-Cyano-2,3-dihydroxy-7-nitroquinoxaline;6-Cyano-7-nitroquinoxaline-2,3-dione;CNQX;FG 9065;FG-9065;FG9065 |
Molecular Weight | 232.15 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H1624071 | Certificate of Analysis | Feb 18, 2024 | C131944 |
A2213363 | Certificate of Analysis | Oct 20, 2023 | C131944 |
A2213378 | Certificate of Analysis | Oct 20, 2023 | C131944 |
A2213380 | Certificate of Analysis | Oct 20, 2023 | C131944 |
Sensitivity | light sensitive |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 3 |
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74. Zhicheng Wang, Shuping Nie, Ru Xia, Yang Lv, Ming Cao, Ming Chen, Qiannian Dong, Lifen Su, Peng Chen, Bin Yang, Jibin Miao, Zhengzhi Zheng, Jiasheng Qian. (2018) Preparation of the Yellow-Colored Aluminum Pigments with Double-Layer Structure Using a Crosslinked Copolymeric Dye. Polymers, 10 (10): (1097). [PMID:30961022] [10.3390/polym10101097] |