Cobimetinib racemate - 99%, high purity , CAS No.934662-91-6

  • ≥99%
Item Number
C649329
Grouped product items
SKUSizeAvailabilityPrice Qty
C649329-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$102.90
C649329-2mg
2mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$83.90
C649329-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$216.90
C649329-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$360.90
C649329-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$960.90
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MAPK/ERK Pathway MEK

Basic Description

SynonymsGDC-0973 racemate; GDC0973 racemate; GDC 0973 racemate; Cobimetinib racemate;XL518 racemate;XL 518 racemate | A922711 | F84878 | HY-13078 | 1-[[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]carbonyl]-3-(piperidin-2-yl)azetidin-3-ol | CS-1043 | MS-
Specifications & Purity≥99%
Biochemical and Physiological MechanismsCobimetinib racemate (GDC-0973 racemate; XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor .
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Cobimetinib racemate (GDC-0973 racemate; XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor .

Form:Solid

Associated Targets(Human)

HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-(3-hydroxy-3-piperidin-2-ylazetidin-1-yl)methanone
INCHI InChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2
InChi Key BSMCAPRUBJMWDF-UHFFFAOYSA-N
Canonical SMILES C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
Isomeric SMILES C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
Alternate CAS 934662-91-6
PubChem CID 51038893
Molecular Weight 531.31

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : ≥ 40 mg/mL (75.29 mM)

Related Documents

Solution Calculators