an NADH ubiquinonereductase inhibitor and a phytotoxic agent
Basic Description
Synonyms
DTXSID401099098 | COCHLIOQUINONE B | (3R,4aR,6aR,12aR,12bR)-3-(2-hydroxypropan-2-yl)-6a,12b-dimethyl-9-[(2S,4S)-4-methyl-3-oxohexan-2-yl]-1,2,3,4a,5,6,12,12a-octahydropyrano[3,2-a]xanthene-8,11-dione | (3R,4aR,6aR,12aR,12bR)-9-[(1S,3S)-1,3-Dimethyl-2-oxop
Specifications & Purity
≥99%
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Product Description
Cochlioquinone B, the minor component of a bioactive pigment isolated from|Bipolaris leersia|, is an NADH ubiquinonereductase inhibitor and a phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A that inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have recently been shown to be antagonists of the human chemokine receptor, CCR5, in HIV-1.
