Basic Description

Synonyms	1,2-anhydro-myo-inositol NIST \| SMR001215828 \| UNII-NHM754Q310 \| AC-36018 \| ((1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol \| Conduritol B-epoxide \| (+/-) Conduritol B epoxide \| (1S,2R,3S,4S,5R,6R)-7-Oxa-bicyclo[4.1.0]heptane-2,3,4,5-tetrao
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Selective, irreversible β-glucosidase inhibitor (IC 50 values are 1 and 100 μM for β-glucosidase and α-glucosidase respectively). Upregulates CD1d expression by THP-1 cells. Raises intracellular glucosylceramide levels. Induces α-synuclein aggregation in
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	(1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
INCHI	InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H/t1-,2-,3+,4+,5-,6+/m0/s1
InChi Key	ZHMWOVGZCINIHW-FTYOSCRSSA-N
Canonical SMILES	C1(C(C(C2C(C1O)O2)O)O)O
Isomeric SMILES	[C@@H]1([C@@H]([C@H]([C@H]2[C@@H]([C@@H]1O)O2)O)O)O
PubChem CID	119054
Molecular Weight	162.14

Enter Lot Number to search for COA:

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3 results found

Lot Number	Certificate Type	Date	Item
J2209110	Certificate of Analysis	Jul 13, 2023	C276443
J2209207	Certificate of Analysis	Jul 13, 2023	C276443
J2209208	Certificate of Analysis	Jul 13, 2023	C276443

Solubility	Soluble in water to 100 mM and in DMSO

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

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SKU	Size	Availability	Price
C276443-25mg	25mg	In stock	$122.90
C276443-100mg	100mg	In stock	$310.90
C276443-250mg	250mg	In stock	$699.90