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contezolid - 98%, high purity , Bacterial 70S ribosome inhibitor, CAS No.1112968-42-9, Bacterial 70S ribosome inhibitor
Basic Description Synonyms ZC0 | CONTEZOLID [INN] | 4(1H)-Pyridinone, 2,3-dihydro-1-(2,3,6-trifluoro-4-((5S)-5-((3-isoxazolylamino)methyl)-2-oxo-3-oxazolidinyl)phenyl)- | GTPL10795 | CS-0016941 | DB12796 | (S)-5-((isoxazol-3-ylamino)methyl)-3-(2,3,5-trifluoro-4-(4-oxo-3,4-dihydropy Specifications & Purity Moligand™, ≥98% Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Bacterial 70S ribosome inhibitor
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (5S)-5-[(1,2-oxazol-3-ylamino)methyl]-3-[2,3,5-trifluoro-4-(4-oxo-2,3-dihydropyridin-1-yl)phenyl]-1,3-oxazolidin-2-one INCHI InChI=1S/C18H15F3N4O4/c19-12-7-13(15(20)16(21)17(12)24-4-1-10(26)2-5-24)25-9-11(29-18(25)27)8-22-14-3-6-28-23-14/h1,3-4,6-7,11H,2,5,8-9H2,(H,22,23)/t11-/m0/s1 InChi Key SULYVXZZUMRQAX-NSHDSACASA-N Canonical SMILES C1CN(C=CC1=O)C2=C(C=C(C(=C2F)F)N3CC(OC3=O)CNC4=NOC=C4)F Isomeric SMILES C1CN(C=CC1=O)C2=C(C=C(C(=C2F)F)N3C[C@@H](OC3=O)CNC4=NOC=C4)F Alternate CAS 1112968-42-9 PubChem CID 25184541 MeSH Entry Terms 4(1H)-Pyridinone, 2,3-dihydro-1-(2,3,6-trifluoro-4-((5S)-5-((3-isoxazolylamino)methyl)-2-oxo-3-oxazolidinyl)phenyl)-;5-((isoxazol-3-ylamino)methyl)-3-(2,3,5-trifluoro-4-(4-oxo-3,4-dihydropyridin-1(2H)-yl)phenyl)oxazolidin-2-one;contezolid;MRX-I compound Molecular Weight 408.30
Chemical and Physical Properties Sensitivity Moisture sensitive；Light sensitive
References 1. Li CR, Zhai QQ, Wang XK, Hu XX, Li GQ, Zhang WX, Pang J, Lu X, Yuan H, Gordeev MF et al. . (2014) In vivo antibacterial activity of MRX-I, a new oxazolidinone.. Antimicrob Agents Chemother, 58 (4): (2418-21). [PMID:24395231 ]
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