Corticosterone - analytical standard, high purity , CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

Item Number
C119329
Grouped product items
SKUSizeAvailabilityPrice Qty
C119329-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$23.90
C119329-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$90.90

Potent endogenous glucocorticoid and mineralocorticoid receptor agonist

Basic Description

Synonyms(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one | A | HMS3713G06 | (11.beta.)-11,21-Dihydroxypregn-4-ene-3,20-dione | Corticosterone, 1mg/ml in Methanol | N
Specifications & PurityMoligand™, analytical standard
Biochemical and Physiological MechanismsCorticosterone is a hormone synthesized in response to stress. It binds and activates MCRs(mineralocorticoid receptors) and GRs (glucocorticoid receptors), which results in altered expression. This eventually affects ionic conductances through the membran
Shipped InNormal
Gradeanalytical standard, Moligand™
Action TypeAGONIST
Mechanism of actionAgonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Corticosteroid is an activator of MCR.

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC22A3 Tchem Solute carrier family 22 member 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SHBG Tchem Sex hormone-binding globulin (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR3C2 Tclin Mineralocorticoid receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SERPINA6 Tchem Corticosteroid-binding globulin (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C2 Tclin Mineralocorticoid receptor (2134 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SERPINA6 Tchem Corticosteroid binding globulin (274 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EBP Tchem 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MTOR Tclin Serine/threonine-protein kinase mTOR (13850 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Caco-2 (12174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A1 Tchem Solute carrier family 22 member 1 (646 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Skin (286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B7 Tchem 3-keto-steroid reductase (330 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THPO Tbio Thrombopoietin (834 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A8 Tclin Solute carrier family 22 member 8 (241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A2 Tchem Solute carrier family 22 member 2 (261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A11 Tclin Solute carrier family 22 member 11 (82 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ERG2 C-8 sterol isomerase (237 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nr1i3 Constitutive androstane receptor (427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Shbg Testis-specific androgen-binding protein (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Galc Galactocerebrosidase (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a6 Solute carrier family 22 member 6 (141 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a5 Solute carrier family 22 member 5 (44 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nr1i2 Nuclear receptor subfamily 1 group I member 2 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a3 Solute carrier family 22 member 3 (35 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a1 Solute carrier organic anion transporter family member 1A1 (265 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a4 Solute carrier organic anion transporter family member 1A4 (114 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1a P-glycoprotein 1 and 3 (MDR1a/MDR1b) (23 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
INCHI InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChi Key OMFXVFTZEKFJBZ-HJTSIMOOSA-N
Canonical SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O
Isomeric SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O
WGK Germany 3
RTECS GM7650000
PubChem CID 5753
Molecular Weight 346.46
Beilstein 2339601

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
A2329516Certificate of AnalysisJan 11, 2023 C119329
A2329595Certificate of AnalysisJan 11, 2023 C119329
J2430118Certificate of AnalysisJan 11, 2023 C119329
D1922087Certificate of AnalysisDec 09, 2022 C119329

Chemical and Physical Properties

SolubilitySoluble in acetone, methanol, ethanol (10 mM), chloroform, and DMSO (100 mM). Insoluble in water.
Specific Rotation[α]+221 to +226 deg(C=1, EtOH)
Melt Point(°C)180-183°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H317:May cause an allergic skin reaction

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

WGK Germany 3
RTECS GM7650000
Merck Index 2538

Related Documents

Citations of This Product

1. Li M et al..  (2017)  Protein Kinase C Mediates the Corticosterone-induced Sensitization of Dorsal Root Ganglion Neurons Innervating the Rat Stomach..  J Neurogastroenterol Motil,  23  (3): (464-476).  [PMID:28343377]
2. Qing Zhu, Yuanshan Han, Ying He, Yilan Fu, Hui Yang, Yun Chen, Yingrui Shi.  (2023)  Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.  Frontiers in Bioscience-Landmark,  28  (11): (311).  [PMID:38062826] [10.31083/j.fbl2811311]
3. Nan Li, Juan Zheng, Lu-Dan Yu, Yuan-Jun Tong, Xinying Gong, Yu Hou, Guosheng Chen, Jianqiao Xu, Fang Zhu, Gangfeng Ouyang.  (2024)  Green, mildly synthesized bismuth-based MOF for extraction of polar glucocorticoids in environmental water.  JOURNAL OF HAZARDOUS MATERIALS,  461  (132477).  [PMID:37716268] [10.1016/j.jhazmat.2023.132477]
4. Junhui He, Dongbo Han, Chunlian Jia, Jiaxiu Xie, Fucui Zhu, Jie Wei, Dongmei Li, Dongmei Wei, Yi Li, Li Tang, Guining Wei, Jing Yan, Yuanming Tong, Lifang Yang, Xuecai Tan.  (2023)  Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression.  Drug Design Development and Therapy,      [PMID:36923105] [10.2147/DDDT.S399183]
5. Yuan Baoshi, Shi Kexin, Zha Juanmin, Cai Yujia, Gu Yue, Huang Kai, Yue Wenchang, Zhai Qiaocheng, Ding Ning, Ren Wenyan, He Weiqi, Xu Ying, Wang Tao.  (2023)  Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway.  Cell Death & Disease,  14  (1): (1-12).  [PMID:36681687] [10.1038/s41419-022-05545-7]
6. Jun Huang, Bin Chen, Hao Wang, Sheng Hu, Xudong Yu, James Reilly, Zhiming He, Yong You, Xinhua Shu.  (2022)  Dihydromyricetin Attenuates Depressive-like Behaviors in Mice by Inhibiting the AGE-RAGE Signaling Pathway.  Cells,  11  (23): (3730).  [PMID:36496991] [10.3390/cells11233730]
7. He Junhui, Li Dongmei, Wei Jie, Wang Sheng, Chu Shifeng, Zhang Zhao, He Fei, Wei Dongmei, Li Yi, Xie Jiaxiu, Lai Kedao, Chen Naihong, Wei Guining.  (2022)  Mahonia Alkaloids (MA) Ameliorate Depression Induced Gap Junction Dysfunction by miR-205/Cx43 Axis.  NEUROCHEMICAL RESEARCH,  47  (12): (3761-3776).  [PMID:36222958] [10.1007/s11064-022-03761-3]
8. Li Sheng, Wang Zhi, Yao Jing Wen, Jiao Hong Chao, Wang Xiao Juan, Lin Hai, Zhao Jing Peng.  (2022)  Reduced PGC-1β protein expression may underlie corticosterone inhibition of mitochondrial biogenesis and oxidative phosphorylation in chicken muscles.  Frontiers in Physiology,  13    [PMID:36311241] [10.3389/fphys.2022.989547]
9. Sun Jia-Yi, Liu Yi-Tong, Jiang Sheng-Nan, Guo Peng-Mei, Wu Xin-Yu, Yu Jia.  (2022)  Essential oil from the roots of Paeonia lactiflora pall. has protective effect against corticosterone-induced depression in mice via modulation of PI3K/Akt signaling pathway.  Frontiers in Pharmacology,  13    [PMID:36188568] [10.3389/fphar.2022.999712]
10. Mingfa Sun, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Haifang Li, Yunlei Zhou, Hai Lin.  (2022)  Research Note: Creatine monohydrate alleviates protein breakdown induced by corticosterone via inhibiting ubiquitin proteasome pathway in chicken myotubes.  POULTRY SCIENCE,  101  (102177).  [PMID:36194918] [10.1016/j.psj.2022.102177]
11. Yumin Liu, Ziqi Hu, Jing Wang, Yanjun Liao, Luan Shu.  (2022)  Puerarin alleviates depressive-like behaviors in high-fat diet-induced diabetic mice via modulating hippocampal GLP-1R/BDNF/TrkB signaling.  NUTRITIONAL NEUROSCIENCE,      [PMID:36039913] [10.1080/1028415X.2022.2112439]
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13. Chai Yuhui, Cai Yawen, Fu Yu, Wang Yingdi, Zhang Yiming, Zhang Xue, Zhu Lingpeng, Miao Mingxing, Yan Tianhua.  (2022)  Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.  Frontiers in Pharmacology,  13    [PMID:35496273] [10.3389/fphar.2022.812362]
14. Jie Liu, Yi Cheng, Yuanjin Zhang, Shengbo Huang, Zongjun Liu, Xin Wang.  (2021)  Lactobacillus rhamnosus induces CYP3A and changes the pharmacokinetics of verapamil in rats.  TOXICOLOGY LETTERS,  352  (46).  [PMID:34600097] [10.1016/j.toxlet.2021.09.010]
15. Huina Li, Kefan Wu, Yue Zhang, Ning Li, Kaijin Wang.  (2020)  Crassifoside H ameliorates depressant behavior in chronic unpredictable mild stress rats by improving HPA axis dysfunction and inhibiting inflammation in hippocampus.  TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH,  19  (8): (1693-1699).  [PMID:] [10.4314/tjpr.v19i8.18]
16. Lan Zhang, Yue Yang, Lei Di, Jun-long Li, Ning Li.  (2020)  Erxian decoction, a famous Chinese medicine formula, antagonizes corticosterone-induced injury in PC12 cells, and improves depression-like behaviours in mice.  PHARMACEUTICAL BIOLOGY,  58  (1): (498-509).  [PMID:32476554] [10.1080/13880209.2020.1765812]
17. Jingjing Liu, Ning Xu, Hong Men, Shuang Li, Yanli Lu, Sze Shin Low, Xin Li, Lihang Zhu, Chen Cheng, Gang Xu, Qingjun Liu.  (2020)  Salivary Cortisol Determination on Smartphone-Based Differential Pulse Voltammetry System.  SENSORS,  20  (5): (1422).  [PMID:32150916] [10.3390/s20051422]
18. Zhang Yingyi, Li Liang, Wang Qi, Shen Mei, Han Weili, Yang Xuemei, Chen Lingyun, Ma Ande, Zhou Zhengzheng.  (2019)  Simultaneous determination of metabolic and elemental markers in methamphetamine-induced hepatic injury to rats using LC-MS/MS and ICP-MS.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  411  (15): (3361-3372).  [PMID:31119349] [10.1007/s00216-019-01810-5]
19. Li-Tao Yi, Rong-Hao Mu, Shu-Qi Dong, Shuang-Shuang Wang, Cheng-Fu Li, Di Geng, Qing Liu.  (2018)  miR-124 antagonizes the antidepressant-like effects of standardized gypenosides in mice.  JOURNAL OF PSYCHOPHARMACOLOGY,      [PMID:29484897] [10.1177/0269881118758304]
20. He Xiaolie, Yang Li, Wang Mei, Zhuang Xizhen, Huang Ruiqi, Zhu Rongrong, Wang Shilong.  (2017)  Targeting the Endocannabinoid/CB1 Receptor System For Treating Major Depression Through Antidepressant Activities of Curcumin and Dexanabinol-Loaded Solid Lipid Nanoparticles.  CELLULAR PHYSIOLOGY AND BIOCHEMISTRY,  42  (6): (2281-2294).  [PMID:28848078] [10.1159/000480001]
21. Mei Yang, Youning Ma, Wenjun Gui, Yiping Ren, Guonian Zhu, Yihua Liu.  (2015)  Determination of 26 endocrine disrupting chemicals in fish and water using modified QuEChERS combined with solid-phase extraction and UHPLC-MS/MS.  Analytical Methods,  (19): (8418-8431).  [PMID:] [10.1039/C5AY01082A]
22. Zhijing Song,Huanyu Gao,Wenchun Xie,Qing Sun,Kai Liang,Yan Li.  (2020-12-29)  Quantitative MALDI-MS assay of steroid hormones in plasma based on hydroxylamine derivatization..  Analytical biochemistry,  616  (114089-114089).  [PMID:33359147]
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References

1. Zhang B et al..  (2020)  Corticosteroid receptor rebalancing alleviates critical illness-related corticosteroid insufficiency after traumatic brain injury by promoting paraventricular nuclear cell survival via Akt/CREB/BDNF signaling..  J Neuroinflammation,  17  (318).  [PMID:33100225]
2. Perry RJ et al..  (2015)  Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes..  Cell,  160  (4): (745-758).  [PMID:25662011]
3. Gao C et al..  (2022)  Naringin Mediates Adult Hippocampal Neurogenesis for Antidepression via Activating CREB Signaling..  Front Cell Dev Biol,  10  (731831).  [PMID:35478969]
4. Li M et al..  (2017)  Protein Kinase C Mediates the Corticosterone-induced Sensitization of Dorsal Root Ganglion Neurons Innervating the Rat Stomach..  J Neurogastroenterol Motil,  23  (3): (464-476).  [PMID:28343377]
5. Zhang B et al..  (2021)  The Dual Dose-Dependent Effects of Corticosterone on Hippocampal Cell Apoptosis After Traumatic Brain Injury Depend on the Activation Ratio of Mineralocorticoid Receptors to Glucocorticoid Receptors..  Front Pharmacol,  12  (713715).  [PMID:34381366]
6. Qing Zhu, Yuanshan Han, Ying He, Yilan Fu, Hui Yang, Yun Chen, Yingrui Shi.  (2023)  Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway.  Frontiers in Bioscience-Landmark,  28  (11): (311).  [PMID:38062826] [10.31083/j.fbl2811311]
7. Nan Li, Juan Zheng, Lu-Dan Yu, Yuan-Jun Tong, Xinying Gong, Yu Hou, Guosheng Chen, Jianqiao Xu, Fang Zhu, Gangfeng Ouyang.  (2024)  Green, mildly synthesized bismuth-based MOF for extraction of polar glucocorticoids in environmental water.  JOURNAL OF HAZARDOUS MATERIALS,  461  (132477).  [PMID:37716268] [10.1016/j.jhazmat.2023.132477]
8. Junhui He, Dongbo Han, Chunlian Jia, Jiaxiu Xie, Fucui Zhu, Jie Wei, Dongmei Li, Dongmei Wei, Yi Li, Li Tang, Guining Wei, Jing Yan, Yuanming Tong, Lifang Yang, Xuecai Tan.  (2023)  Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression.  Drug Design Development and Therapy,      [PMID:36923105] [10.2147/DDDT.S399183]
9. Yuan Baoshi, Shi Kexin, Zha Juanmin, Cai Yujia, Gu Yue, Huang Kai, Yue Wenchang, Zhai Qiaocheng, Ding Ning, Ren Wenyan, He Weiqi, Xu Ying, Wang Tao.  (2023)  Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway.  Cell Death & Disease,  14  (1): (1-12).  [PMID:36681687] [10.1038/s41419-022-05545-7]
10. Jun Huang, Bin Chen, Hao Wang, Sheng Hu, Xudong Yu, James Reilly, Zhiming He, Yong You, Xinhua Shu.  (2022)  Dihydromyricetin Attenuates Depressive-like Behaviors in Mice by Inhibiting the AGE-RAGE Signaling Pathway.  Cells,  11  (23): (3730).  [PMID:36496991] [10.3390/cells11233730]
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