Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C609571-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,334.90 | |
C609571-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,001.90 |
Synonyms | J-515608 | CS-B0344 | 3-(4-bromo-2,6-difluorobenzyloxy)-5-[3-[4-(1-pyrrolidinyl)butyl]ureido]isothiazole-4-carboxamide | PAN 90806 | NCGC00263100-04 | DTXSID801005320 | DTXSID00179866 | HXHAJRMTJXHJJZ-UHFFFAOYSA-N | W1B375O5M2 | 3-[(4-bromo-2,6-difluoroph |
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Specifications & Purity | Moligand™ |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Vascular endothelial growth factor receptor 2 inhibitor |
ALogP | 3.7 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-(4-pyrrolidin-1-ylbutylcarbamoylamino)-1,2-thiazole-4-carboxamide |
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INCHI | InChI=1S/C20H24BrF2N5O3S/c21-12-9-14(22)13(15(23)10-12)11-31-18-16(17(24)29)19(32-27-18)26-20(30)25-5-1-2-6-28-7-3-4-8-28/h9-10H,1-8,11H2,(H2,24,29)(H2,25,26,30) |
InChi Key | HXHAJRMTJXHJJZ-UHFFFAOYSA-N |
Canonical SMILES | C1CCN(C1)CCCCNC(=O)NC2=C(C(=NS2)OCC3=C(C=C(C=C3F)Br)F)C(=O)N |
Isomeric SMILES | C1CCN(C1)CCCCNC(=O)NC2=C(C(=NS2)OCC3=C(C=C(C=C3F)Br)F)C(=O)N |
PubChem CID | 9811611 |
Molecular Weight | 532.42 |
PubChem CID | 9811611 |
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CAS Registry No. | 252003-65-9 |
ChEMBL Ligand | CHEMBL253969 |
RCSB PDB Ligand | BFF |
Enter Lot Number to search for COA:
1. Beebe JS, Jani JP, Knauth E, Goodwin P, Higdon C, Rossi AM, Emerson E, Finkelstein M, Floyd E, Harriman S et al.. (2003) Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.. Cancer Res, 63 (21): (7301-9). [PMID:14612527] [10.1021/op500134e] |