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CP21R7 (CP21) - 98%, high purity , CAS No.125314-13-8

≥98%

CAS#: 125314-13-8
Formula: C₁₉H₁₅N₃O₂
Molecular Weight: 317.34
PubChem CID: 5327711

Item Number

C413888

Grouped product items
SKU	Size	Availability	Price
C413888-5mg	5mg	In stock	$129.90
C413888-10mg	10mg	In stock	$189.90
C413888-25mg	25mg	In stock	$343.90
C413888-50mg	50mg	In stock	$581.90
C413888-100mg	100mg	In stock	$937.90

GSK-3β Selective Inhibitors | Activators

Basic Description

Synonyms	3-(3-Aminophenyl)-4-(1-methyl-1H-indol-3-yl)pyrrole-2,5-dione； CP21
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	CP21R7 (CP21) is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information CP21R7 (CP21) is a potent and selectiveGSK-3βinhibitor that can potently activate canonical Wnt signalling. Targets GSK-3β (Cell-free assay)

ALogP

2.315

HBD Count

Rotatable Bond

Associated Targets(Human)

GSK3B Tclin Glycogen synthase kinase-3 beta (1 Activities)

Discover Target: GSK3B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)

Discover Target: GSK3B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PRKCG Tchem Protein kinase C gamma (2471 Activities)

Discover Target: PRKCG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PRKCA Tchem Protein kinase C alpha (5923 Activities)

Discover Target: PRKCA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	3-(3-aminophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione
INCHI	InChI=1S/C19H15N3O2/c1-22-10-14(13-7-2-3-8-15(13)22)17-16(18(23)21-19(17)24)11-5-4-6-12(20)9-11/h2-10H,20H2,1H3,(H,21,23,24)
InChi Key	RGTAEYDIDMGJLX-UHFFFAOYSA-N
Canonical SMILES	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC(=CC=C4)N
Isomeric SMILES	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC(=CC=C4)N
PubChem CID	5327711
Molecular Weight	317.34

Certificates

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5 results found

Lot Number	Certificate Type	Date	Item
K2229139	Certificate of Analysis	Sep 11, 2024	C413888
K2229140	Certificate of Analysis	Sep 11, 2024	C413888
K2229141	Certificate of Analysis	Sep 11, 2024	C413888
K2229142	Certificate of Analysis	Sep 11, 2024	C413888
K2229149	Certificate of Analysis	Sep 11, 2024	C413888

Solubility

Solubility (25°C) In vitro DMSO: 63 mg/mL (198.52 mM); Ethanol: 1 mg/mL warmed with 50ºC Water: bath (3.15 mM); Water: Insoluble;

DMSO(mg / mL) Max Solubility

DMSO(mM) Max Solubility

198.5252411

Water(mg / mL) Max Solubility

＜1

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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