CRAC channel inhibitor 5b , CAS No.C609599, Channel blocker of Orai1

Item Number
C609599
Grouped product items
SKUSizeAvailabilityPrice Qty
C609599-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
C609599-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
View related series
Orai1 Channel blocker

Basic Description

Specifications & PurityMoligand™
GradeMoligand™
Action TypeCHANNEL BLOCKER
Mechanism of actionChannel blocker of Orai1

Associated Targets(Human)

ORAI1 Tchem Calcium release-activated calcium channel protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-(4-chlorophenyl)-1,3-dimethyl-3-[1-(4-methylphenyl)propyl]urea
INCHI InChI=1S/C19H23ClN2O/c1-5-18(15-8-6-14(2)7-9-15)22(4)19(23)21(3)17-12-10-16(20)11-13-17/h6-13,18H,5H2,1-4H3
InChi Key YPDVKFTYHRFBSZ-UHFFFAOYSA-N
Canonical SMILES CCC(N(C(=O)N(c1ccc(cc1)Cl)C)C)c1ccc(cc1)C
PubChem CID 134813903

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Related Documents

References

1. Zhang HZ, Xu XL, Chen HY, Ali S, Wang D, Yu JW, Xu T, Nan FJ.  (2015)  Discovery and structural optimization of 1-phenyl-3-(1-phenylethyl)urea derivatives as novel inhibitors of CRAC channel..  Acta Pharmacol Sin,  36  (9): (1137-44).  [PMID:26256403]

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