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Crotaline - 10mM in DMSO, high purity , CAS No.315-22-0

10mM in DMSO

CAS#: 315-22-0
Formula: C₁₆H₂₃NO₆
Molecular Weight: 325.36
Beilstein Registry Number: 48732
PubChem CID: 9415

Item Number

C423269

Grouped product items
SKU	Size	Availability	Price	Qty
C423269-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$47.90

Basic Description

Synonyms	monocrotaline\|Crotaline\|315-22-0\|Monocrotalin\|(-)-Monocrotaline\|CHEBI:6980\|Retronecine cyclic 2,3-dihydroxy-2,3,4-trimethylglutarate\|(13-alpha,14-alpha)-14,19-Dihydro-12,13-dihydroxy-20-norcrotalanan-11,15-dione\|MLS002153902\|DTXSID9020902\|NCI-C56462\|14,19
Specifications & Purity	10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Monocrotaline is a toxic, pyrrolizidine alkaloid. It is used for inducing pulmonary diseases in rats. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. A toxic, pyrrolizidine alkaloid

Associated Targets

GMNN Tbio Geminin 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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ACHE Tclin Acetylcholinesterase 0 Activities

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THRB Tclin Thyroid hormone receptor beta 0 Activities

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BCHE Tclin Cholinesterase 0 Activities

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TP53 Tchem Cellular tumor antigen p53 0 Activities

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Names and Identifiers

IUPAC Name	(1R,4R,5R,6R,16R)-5,6-dihydroxy-4,5,6-trimethyl-2,8-dioxa-13-azatricyclo[8.5.1.013,16]hexadec-10-ene-3,7-dione
INCHI	InChI=1S/C16H23NO6/c1-9-13(18)23-11-5-7-17-6-4-10(12(11)17)8-22-14(19)16(3,21)15(9,2)20/h4,9,11-12,20-21H,5-8H2,1-3H3/t9-,11+,12+,15+,16-/m0/s1
InChi Key	QVCMHGGNRFRMAD-XFGHUUIASA-N
Canonical SMILES	CC1C(=O)OC2CCN3C2C(=CC3)COC(=O)C(C1(C)O)(C)O
Isomeric SMILES	C[C@H]1C(=O)O[C@@H]2CCN3[C@@H]2C(=CC3)COC(=O)[C@]([C@]1(C)O)(C)O
WGK Germany	3
RTECS	QB3140000
PubChem CID	9415
UN Number	1544
Molecular Weight	325.36
Beilstein	48732

Sensitivity

Light sensitive

Melt Point(°C)

204°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H351:Suspected of causing cancer
Precautionary Statements	P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/... P281:Use personal protective equipment as required.
WGK Germany	3
RTECS	QB3140000

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