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Curcumin analog C1 - 97%, high purity , CAS No.39777-61-2

  • ≥97%
Item Number
C413625
Grouped product items
SKUSizeAvailabilityPrice Qty
C413625-5mg
5mg
In stock
$171.90
C413625-10mg
10mg
In stock
$274.90
C413625-25mg
25mg
In stock
$549.90
C413625-50mg
50mg
In stock
$892.90
C413625-100mg
100mg
In stock
$1,441.90
C413625-200mg
200mg
In stock
$2,300.90
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Basic Description

SynonymsMFCD00719180 | (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1, | AB00092085-01 | TFEB activator 1 | D82401 | BDBM50285603 | TFEB activator 1; ABM-7612 | S6769 | 1,5-bis-(2-methoxyphenyl)-1,4-pentadien-3-one | 1,5-bis(2-methoxyphenyl)-1,4-pentadien-3-one | (1E,4E
Specifications & Purity≥97%
Biochemical and Physiological MechanismsTFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway an
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

Curcumin analog C1 (Curcumin analog Compound C1) is a potenttranscription factor EB (TFEB)activator with promise for the prevention or treatment of Alzheimer's disease.

Associated Targets(Human)

HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RPMI-7951 (420 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (1E,4E)-1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one
INCHI InChI=1S/C19H18O3/c1-21-18-9-5-3-7-15(18)11-13-17(20)14-12-16-8-4-6-10-19(16)22-2/h3-14H,1-2H3/b13-11+,14-12+
InChi Key RCZMPCUUTSDNAJ-PHEQNACWSA-N
Canonical SMILES COC1=CC=CC=C1C=CC(=O)C=CC2=CC=CC=C2OC
Isomeric SMILES COC1=CC=CC=C1/C=C/C(=O)/C=C/C2=CC=CC=C2OC
PubChem CID 830608
Molecular Weight 294.34

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
J2214467Certificate of AnalysisJun 21, 2022 C413625
J2214499Certificate of AnalysisJun 21, 2022 C413625
J2214531Certificate of AnalysisJun 21, 2022 C413625
J2214532Certificate of AnalysisJun 21, 2022 C413625
J2214533Certificate of AnalysisJun 21, 2022 C413625
J2214534Certificate of AnalysisJun 21, 2022 C413625

Chemical and Physical Properties

SolubilityDMSO: 59 mg/mL (200.45 mM)Ethanol: 2 mg/mL (6.79 mM)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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