Cyclamic acid - ≥98%, high purity , CAS No.100-88-9, Antagonist of TAS2R31;Antagonist of TAS2R43

1 Citations
Item Number
C129435
Grouped product items
SKUSizeAvailabilityPrice Qty
C129435-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
C129435-25g
25g
In stock
$28.90
C129435-100g
100g
In stock
$102.90
C129435-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$461.90

Potent TAS 1 R 3 ligand

Basic Description

SynonymsE78799 | Cyclamic acid (USAN) | Cyclohexylamide sulfate | s4015 | Cyclamsaeure | HMS3264K03 | Cyclohexylamine sulfamic acid | N-Cyclohexyl-Sulfuric acid monoamide | AB01563182_02 | CALCIUMLEVULINATE | cyclamic-acid | MFCD00065234 | CYCLAMIC ACID [MI] | Cy
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsA non-nutritive sweetener.Potent TAS 1 R 3 ligand. Binds to the transmembrane domain of TAS 1 R 3 . Action is unaffected by umami compounds. Putative carcinogenic agent in vivo. Orally active.
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of TAS2R31;Antagonist of TAS2R43
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.
A useful biochemical reagent.

Associated Targets(Human)

TAS2R43 Tchem Taste receptor type 2 member 43 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TAS2R31 Tchem Taste receptor type 2 member 31 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TAS1R2 Tbio Taste receptor type 1 member 2 (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TAS1R3 Tbio Taste receptor type 1 member 3 (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TAS2R31 Tchem Taste receptor type 2 member 31 (86 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TAS1R3 Tbio T1R1/T1R3 (473 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chrm1 Muscarinic acetylcholine receptor (3770 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name cyclohexylsulfamic acid
INCHI InChI=1S/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)
InChi Key HCAJEUSONLESMK-UHFFFAOYSA-N
Canonical SMILES C1CCC(CC1)NS(=O)(=O)O
Isomeric SMILES C1CCC(CC1)NS(=O)(=O)O
WGK Germany 2
RTECS GV6950000
Alternate CAS 100-88-9
PubChem CID 7533
NSC Number 220327
MeSH Entry Terms Calcium Cyclamate;Cyclamate;Cyclamate Calcium (2:1) Salt;Cyclamate, Calcium;Cyclamate, Calcium (2:1) Salt, Dihydrate;Cyclamate, Potassium;Cyclamate, Sodium;Cyclamate, Sodium Salt;Cyclamates;Cyclamic Acid;Potassium Cyclamate;Sodium Cyclamate
Molecular Weight 179.24
Beilstein 2208885
Reaxy-Rn 2208885

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
F2413307Certificate of AnalysisApr 28, 2024 C129435
F2413308Certificate of AnalysisApr 28, 2024 C129435
F2413065Certificate of AnalysisSep 23, 2022 C129435
K2230653Certificate of AnalysisSep 23, 2022 C129435
K2230717Certificate of AnalysisSep 23, 2022 C129435
K2230718Certificate of AnalysisSep 23, 2022 C129435

Chemical and Physical Properties

SolubilityDMSO 36 mg/mL Water 36 mg/mL Ethanol 36 mg/mL
Melt Point(°C)169 °C(dec.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 2
RTECS GV6950000
Reaxy-Rn 2208885
Merck Index 2703

Related Documents

Citations of This Product

1. Zirong Li, Jiancheng Luo, Jun Wang, Yuanyuan Yu, Qiang Wang, Ping Wang.  (2023)  An eco-friendly technique for shrink-resist finishing of dyed wool via combined use of hydrolase and cyclamate.  Journal of Cleaner Production,  427  (15): (139276).  [PMID:10523301]

References

1. Zirong Li, Jiancheng Luo, Jun Wang, Yuanyuan Yu, Qiang Wang, Ping Wang.  (2023)  An eco-friendly technique for shrink-resist finishing of dyed wool via combined use of hydrolase and cyclamate.  Journal of Cleaner Production,  427  (15): (139276).  [PMID:10523301]

Solution Calculators