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Cyclamic acid - ≥98%, high purity , CAS No.100-88-9, Antagonist of TAS2R31;Antagonist of TAS2R43

Moligand™
≥98%

CAS#: 100-88-9
Formula: C₆H₁₃NO₃S
Molecular Weight: 179.24
Beilstein Registry Number: 2208885
EC Number: 202-898-1
MDL number: MFCD00065234
PubChem CID: 7533

Item Number

C129435

Grouped product items
SKU	Size	Availability	Price
C129435-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$9.90
C129435-25g	25g	In stock	$28.90
C129435-100g	100g	In stock	$102.90
C129435-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$461.90

Potent TAS 1 R 3 ligand

View related series

TAS2R31 Antagonist TAS2R43 Antagonist

Basic Description

Synonyms	Cyclamic acid\|Cyclohexylsulfamic acid\|100-88-9\|Cyclohexanesulfamic acid\|CYCLAMATE\|N-Cyclohexylsulfamic acid\|Hexamic acid\|Sucaryl\|Sucaryl acid\|Cyclohexylaminesulphonic acid\|Sulfamic acid, cyclohexyl-\|N-Cyclohexylsulphamic acid\|Cyclohexylamidosulfuric acid\|
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	A non-nutritive sweetener.Potent TAS 1 R 3 ligand. Binds to the transmembrane domain of TAS 1 R 3 . Action is unaffected by umami compounds. Putative carcinogenic agent in vivo. Orally active.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of TAS2R31;Antagonist of TAS2R43
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners. A useful biochemical reagent.

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS1R3 Tbio Taste receptor type 1 member 3 0 Activities

Discover Target: TAS1R3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R43 Tchem Taste receptor type 2 member 43 0 Activities

Discover Target: TAS2R43

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS1R2 Tbio Taste receptor type 1 member 2 0 Activities

Discover Target: TAS1R2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM5 Tclin Muscarinic acetylcholine receptor M5 0 Activities

Discover Target: CHRM5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R31 Tchem Taste receptor type 2 member 31 0 Activities

Discover Target: TAS2R31

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	cyclohexylsulfamic acid
INCHI	InChI=1S/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)
InChi Key	HCAJEUSONLESMK-UHFFFAOYSA-N
Canonical SMILES	C1CCC(CC1)NS(=O)(=O)O
Isomeric SMILES	C1CCC(CC1)NS(=O)(=O)O
WGK Germany	2
RTECS	GV6950000
Alternate CAS	100-88-9
PubChem CID	7533
NSC Number	220327
MeSH Entry Terms	Calcium Cyclamate;Cyclamate;Cyclamate Calcium (2:1) Salt;Cyclamate, Calcium;Cyclamate, Calcium (2:1) Salt, Dihydrate;Cyclamate, Potassium;Cyclamate, Sodium;Cyclamate, Sodium Salt;Cyclamates;Cyclamic Acid;Potassium Cyclamate;Sodium Cyclamate
Molecular Weight	179.24
Beilstein	2208885
Reaxy-Rn	2208885

Certificates

Certificate of Analysis(COA)

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6 results found

Lot Number	Certificate Type	Date	Item
F2413307	Certificate of Analysis	Apr 28, 2024	C129435
F2413308	Certificate of Analysis	Apr 28, 2024	C129435
F2413065	Certificate of Analysis	Sep 23, 2022	C129435
K2230653	Certificate of Analysis	Sep 23, 2022	C129435
K2230717	Certificate of Analysis	Sep 23, 2022	C129435
K2230718	Certificate of Analysis	Sep 23, 2022	C129435

Solubility

DMSO 36 mg/mL Water 36 mg/mL Ethanol 36 mg/mL

Melt Point(°C)

169 °C(dec.)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	2
RTECS	GV6950000
Reaxy-Rn	2208885
Merck Index	2703

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