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Cycloheximide - 95%, high purity , 80S Ribosome inhibitor, CAS No.66-81-9, 80S Ribosome inhibitor

27 Citations
Item Number
C112766
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C112766-250mg
250mg
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$29.90
C112766-1g
1g
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$78.90
C112766-5g
5g
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$214.90
C112766-25g
25g
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Protein synthesis inhibitor

View related series
Antibiotics FKBP prolyl isomerase 1A Inhibitor

Basic Description

SynonymsACTIDIONE | C15H23NO4 | Neocycloheximide | Naramycin | Cicloheximidum | Cicloheximida | U 4527 | Actispray | cycloheximide | Actidion | Actidione PM | Hizarocin | Kaken | NARAMYCIN A | NSC-185 | Acti-Aid | NSC 185 | Cicloheximide | Cycloheximide [USAN] |
Specifications & PurityMoligand™, ≥95%
Biochemical and Physiological MechanismsCell permeable: yes Primary Target translocase enzyme Reversible: yes.Protein synthesis inhibitor. Antifungal antibiotic.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of action80S Ribosome inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Cycloheximide, also known as Actidione, is a glutarimide antibiotic commonly derived from the bacterium Streptomyces griseus. It acts as a potent inhibitor of protein biosynthesis in eukaryotic cells by disrupting the translocation step during translation, effectively blocking translational elongation.


Application：

In yeast strains, cycloheximide has been used as a protein synthesis inhibitor in the cycloheximide chase experiment.
It has been used to inhibit translation in mammalian cells.
It has been used to suppress fungal growth. 

Product Properties

ALogP0.5

Associated Targets(Human)

FKBP1A Tclin Peptidyl-prolyl cis-trans isomerase FKBP1A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EIF4A1 Tchem Eukaryotic initiation factor 4A-I (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC2A1 Tchem Solute carrier family 2, facilitated glucose transporter member 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FKBP1A Tclin FK506-binding protein 1A (1014 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Benjaminiella (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pyricularia grisea (1253 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas (460 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas fluorescens (1630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Legionella pneumophila (143 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pasteurella multocida (1166 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pyogenes (16140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus flavus (8875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus niger (16508 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus thuringiensis (718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mucor (407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus cereus (7522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Priestia megaterium (1154 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Yarrowia lipolytica (267 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Zygosaccharomyces bailii (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei (78846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Microbotryum violaceum (192 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium oxysporum (3998 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium berghei (192651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium yoelii (6656 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human betaherpesvirus 5 (5122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mucor mucedo (338 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Parastagonospora nodorum (325 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phoma (9 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus pseudoglaucus (84 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180018
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180018
IUPAC Name 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
INCHI InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChi Key YPHMISFOHDHNIV-FSZOTQKASA-N
Canonical SMILES CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C
Isomeric SMILES C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C
PubChem CID 6197
UN Number 2588
Packing Group I
Molecular Weight 281.35

Certificates

Certificate of Analysis(COA)

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37 results found

Lot NumberCertificate TypeDateItem
K2411194Certificate of AnalysisOct 30, 2024 C112766
K2411196Certificate of AnalysisOct 30, 2024 C112766
K2411195Certificate of AnalysisOct 30, 2024 C112766
H2428334Certificate of AnalysisAug 12, 2024 C112766
H2428333Certificate of AnalysisAug 12, 2024 C112766
H2428332Certificate of AnalysisAug 12, 2024 C112766
E2430123Certificate of AnalysisApr 02, 2024 C112766
E2430124Certificate of AnalysisApr 02, 2024 C112766
E2430132Certificate of AnalysisApr 02, 2024 C112766
D2402171Certificate of AnalysisMar 18, 2024 C112766
D2402438Certificate of AnalysisMar 18, 2024 C112766
G2322209Certificate of AnalysisJun 19, 2023 C112766
L2314039Certificate of AnalysisJun 19, 2023 C112766
G2322216Certificate of AnalysisJun 19, 2023 C112766
G2322211Certificate of AnalysisJun 19, 2023 C112766
G2322207Certificate of AnalysisJun 19, 2023 C112766
G2322200Certificate of AnalysisJun 19, 2023 C112766
G2322198Certificate of AnalysisJun 19, 2023 C112766
G2322190Certificate of AnalysisJun 19, 2023 C112766
G2322201Certificate of AnalysisJun 19, 2023 C112766
B2328235Certificate of AnalysisOct 25, 2022 C112766
K2215712Certificate of AnalysisOct 25, 2022 C112766
K2215711Certificate of AnalysisOct 25, 2022 C112766
K2215710Certificate of AnalysisOct 25, 2022 C112766
K2215707Certificate of AnalysisOct 25, 2022 C112766
I2216057Certificate of AnalysisSep 16, 2022 C112766
E2331179Certificate of AnalysisJun 29, 2022 C112766
C2331048Certificate of AnalysisJun 29, 2022 C112766
H2203127Certificate of AnalysisJun 29, 2022 C112766
H2203126Certificate of AnalysisJun 29, 2022 C112766
H2203125Certificate of AnalysisJun 29, 2022 C112766
H2203124Certificate of AnalysisJun 29, 2022 C112766
F2208464Certificate of AnalysisFeb 22, 2022 C112766
C2226419Certificate of AnalysisFeb 22, 2022 C112766
C2226417Certificate of AnalysisFeb 22, 2022 C112766
C2226219Certificate of AnalysisFeb 22, 2022 C112766
C2226181Certificate of AnalysisFeb 22, 2022 C112766

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Chemical and Physical Properties

SolubilitySoluble in DMSO, acetone, ethanol and methanol. Slightly soluble in water with sonication
SensitivityLight sensitive
Flash Point(°F)230°F
Flash Point(°C)>110°C
Boil Point(°C)492°C
Melt Point(°C)119.5-121°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS09
Signal Danger
Hazard Statements

H341:Suspected of causing genetic defects

H411:Toxic to aquatic life with long lasting effects

H300:Fatal if swallowed

H360D:May damage the unborn child

Precautionary Statements

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P281:Use personal protective equipment as required.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P410:Protect from sunlight.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

Class 6.1

Related Documents

 SDS

 Specification Sheet

Alternative Products

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    Cycloheximide (NSC-185)

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11. Ziyuan Tong, Yuan Shen, Quan Yuan, Honghao Yu.  (2023)  HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH,  1870  (119553).  [PMID:37527738] [10.1016/j.bbamcr.2023.119553]
12. Xing Zeyu, Zhen Yanhua, Chen Jie, Du Mingyang, Li Dongdong, Liu Ruyin, Zheng Jiahe.  (2023)  KPNA2 Silencing, Regulated by E3 Ubiquitin Ligase FBXW7, Alleviates Endothelial Dysfunction and Inflammation Through Inhibiting the Nuclear Translocation of p65 and IRF3: A Possible Therapeutic Approach for Atherosclerosis.  INFLAMMATION,    (1-18).  [PMID:37432596] [10.1007/s10753-023-01863-w]
13. Yuan Qingling, Fan Yuxia, Liu Zheng, Wang Xiaoming, Jia Meng, Dong Yongqiang, Geng Zushi, Zheng Jian, Lu Xiubo.  (2023)  Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.  APOPTOSIS,    (1-17).  [PMID:37336836] [10.1007/s10495-023-01861-1]
14. Yu Li, Qian He, Chao-Yong He, Chao Cai, Zhen Chen, Jing-Zhu Duan.  (2023)  Activating transcription factor 4 drives the progression of diabetic cardiac fibrosis.  ESC Heart Failure,      [PMID:37290760] [10.1002/ehf2.14404]
15. Cheng Jian, Zhang Guizhong, Deng Tian, Liu Zhao, Zhang Mengqi, Zhang Pengchao, Adeshakin Funmilayo O., Niu Xiangyun, Yan Dehong, Wan Xiaochun, Yu Guang.  (2023)  CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.  Cell Death & Disease,  14  (5): (1-11).  [PMID:37210387] [10.1038/s41419-023-05858-1]
16. Xu Rongmei, Wan Min, Shi Xuemeng, Ma Shumin, Zhang Lina, Yi Ping, Zhang Rongying.  (2023)  A Rab10–ACAP1–Arf6 GTPases cascade modulates M4 muscarinic acetylcholine receptor trafficking and signaling.  CELLULAR AND MOLECULAR LIFE SCIENCES,  80  (4): (1-22).  [PMID:36917255] [10.1007/s00018-023-04722-x]
17. Adzraku Seyram Yao, Wang Guozhang, Cao Can, Bao Yurong, Wang Yizhou, Smith Alhaji Osman, Du Yuwei, Wang Haiyang, Li Yue, Xu Kailin, Qiao Jianlin, Ju Wen, Zeng Lingyu.  (2023)  Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.  CELLULAR & MOLECULAR BIOLOGY LETTERS,  28  (1): (1-23).  [PMID:36647012] [10.1186/s11658-022-00413-w]
18. Wu Zhuhua, Zhu Li, Nie Xinran, Wei Li, Qi Yong.  (2023)  USP15 promotes pulmonary vascular remodeling in pulmonary hypertension in a YAP1/TAZ-dependent manner.  EXPERIMENTAL AND MOLECULAR MEDICINE,  55  (1): (183-195).  [PMID:36635430] [10.1038/s12276-022-00920-y]
19. Xiaosong Wei, Beibei Wang, Zixin Wu, Xiaoming Yang, Yufeng Guo, Yang Yang, Zhiwei Fang, Chengzhi Yi, Liuhui Zhang, Xin Fan, Lirong Zhang, Dongkui Song.  (2023)  WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity.  CANCER LETTERS,  556  (216058).  [PMID:36627049] [10.1016/j.canlet.2023.216058]
20. Dingyou Wang, Yuke Ji, Rui Wang, Ke Cheng, Liang Liu, Na Wu, Qing Tang, Xu Zheng, Junxia Li, Zhilong Zhu, Qinghua Wang, Xueyan Zhang, Runbo Li, Jinjin Pan, Zheng Sui, Yuhui Yuan.  (2022)  Lycopene Ameliorates Hypoxic Pulmonary Hypertension via Suppression of Oxidative Stress.  Oxidative Medicine and Cellular Longevity,  2022  (9179427).  [PMID:] [10.1155/2022/9179427]
21. Jin-hua Fan, Min-min Xu, Li-ming Zhou, Zheng-wei Gui, Lu Huang, Xue-gang Li, Xiao-li Ye.  (2022)  Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.  PHYTOMEDICINE,  96  (153881).  [PMID:34942456] [10.1016/j.phymed.2021.153881]
22. Tingting Chen, Yichen Guo, Jinjun Shan, Jiarui Zhang, Xu Shen, Jun Guo, Xiaoguang Margaret Liu.  (2019)  Vector Analysis of Cytoskeletal Structural Tension and the Mechanisms that Underpin Spectrin-Related Forces in Pyroptosis.  ANTIOXIDANTS & REDOX SIGNALING,  30  (12): (1503-1520).  [PMID:29669427] [10.1089/ars.2017.7366]
23. Bingxiang Zhao, Sufang Gu, Yong Du, Minjie Shen, Xiangrui Liu, Youqing Shen.  (2018)  Solid lipid nanoparticles as carriers for oral delivery of hydroxysafflor yellow A.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  535  (164).  [PMID:29107614] [10.1016/j.ijpharm.2017.10.040]
24. Ji Zheng, Chao Su, Jianwen Zhou, Like Xu, Yanyun Qian, Hong Chen.  (2017)  Effects and mechanisms of ultraviolet, chlorination, and ozone disinfection on antibiotic resistance genes in secondary effluents of municipal wastewater treatment plants.  CHEMICAL ENGINEERING JOURNAL,  317  (309).  [PMID:] [10.1016/j.cej.2017.02.076]
25. Li Jianan, Cheng Weixiao, Xu Like, Jiao Yanan, Baig Shams Ali, Chen Hong.  (2016)  Occurrence and removal of antibiotics and the corresponding resistance genes in wastewater treatment plants: effluents’ influence to downstream water environment.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  23  (7): (6826-6835).  [PMID:26658782] [10.1007/s11356-015-5916-2]
26. Wan Min, Zhang Wenhua, Tian Yangli, Xu Chanjuan, Xu Tao, Liu Jianfeng, Zhang Rongying.  (2015)  Unraveling a molecular determinant for clathrin-independent internalization of the M2 muscarinic acetylcholine receptor.  Scientific Reports,  5  (1): (1-16).  [PMID:26094760] [10.1038/srep11408]
27. Li Jianan, Cheng Weixiao, Xu Like, Strong P. J., Chen Hong.  (2015)  Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  22  (6): (4587-4596).  [PMID:25323405] [10.1007/s11356-014-3665-2]

References

1. Christner C, Wyrwa R, Marsch S, Küllertz G, Thiericke R, Grabley S, Schumann D, Fischer G.  (1999)  Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties..  J Med Chem,  42  (18): (3615-22).  [PMID:10479292] [10.1021/op500134e]
2. Xu C et al..  (2021)  ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/ß-Catenin Signaling..  Mol Cancer Res,  19  (9): (1441-1453).  [PMID:34158395]
3. Zhao S et al..  (2019)  BAG3 promotes autophagy and glutaminolysis via stabilizing glutaminase..  Cell Death Dis,  10  (4): (284).  [PMID:30910998]
4. Nilchian A et al..  (2019)  CXADR-Mediated Formation of an AKT Inhibitory Signalosome at Tight Junctions Controls Epithelial-Mesenchymal Plasticity in Breast Cancer..  Cancer Res,  79  (47-60).  [PMID:30385615]
5. Stretton C et al..  (2015)  GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling..  Biochem J,  470  (2): (207-21).  [PMID:26348909]
6. Chen J et al..  (2019)  Heat shock protein 47 (HSP47) binds to discoidin domain-containing receptor 2 (DDR2) and regulates its protein stability..  J Biol Chem,  294  (45): (16846-16854).  [PMID:31570520]
7. Liu X et al..  (2016)  HSP90 inhibits apoptosis and promotes growth by regulating HIF-1a abundance in hepatocellular carcinoma..  Int J Mol Med,  37  (3): (825-35).  [PMID:26846697]
8. Xu Q et al..  (2017)  HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma..  Mol Cancer,  16  (178).  [PMID:29262861]
9. Chan C et al..  (2017)  Incompatibility of chemical protein synthesis inhibitors with accurate measurement of extended protein degradation rates..  Pharmacol Res Perspect,  5  (5):   [PMID:28971619]
10. Salvatori R et al..  (2017)  In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism..  Eur J Endocrinol,  177  (3): (257-266).  [PMID:28634279]
11. Yoshihara T et al..  (2018)  Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice..  PLoS Genet,  14  (8): (e1007545).  [PMID:30114188]
12. Mancini A et al..  (2020)  LGR4 deficiency results in delayed puberty through impaired Wnt/ß-catenin signaling..  JCI Insight,  5  (11):   [PMID:32493844]
13. Chu Y et al..  (2021)  LUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG13..  Autophagy,  17  (7): (1684-1699).  [PMID:32543267]
14. Moon HJ et al..  (2013)  MCF-7 Cells Expressing Nuclear Associated Lysyl Oxidase-like 2 (LOXL2) Exhibit an Epithelial-to-Mesenchymal Transition (EMT) Phenotype and Are Highly Invasive in Vitro..  J Biol Chem,  288  (42): (30000-8).  [PMID:24014025]
15. Xu S et al..  (2022)  MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS..  PLoS Pathog,  18  (2): (e1010299).  [PMID:35171955]
16. Flocke LS et al..  (2016)  Molecular mode of action of NKP-1339 - a clinically investigated ruthenium-based drug - involves ER- and ROS-related effects in colon carcinoma cell lines..  Invest New Drugs,  34  (3): (261-8).  [PMID:26988975]
17. Wang CI et al..  (2016)  mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells..  Oncotarget,  7  (18): (25432-42).  [PMID:27009856]
18. Li W et al..  (2021)  SARS-CoV-2 Nsp5 Activates NF-?B Pathway by Upregulating SUMOylation of MAVS..  Front Immunol,  12  (750969).  [PMID:34858407]
19. Gao G et al..  (2021)  TGF-ß1 Facilitates TAp63a Protein Lysosomal Degradation to Promote Pancreatic Cancer Cell Migration..  Biology (Basel),  10  (7):   [PMID:34203341]
20. Drever BD et al..  (2008)  The seed extract of Cassia obtusifolia offers neuroprotection to mouse hippocampal cultures..  J Pharmacol Sci,  107  (4): (380-92).  [PMID:18719316]
21. Trondl R et al..  (2014)  Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells..  Mol Pharmacol,  85  (3): (451-9).  [PMID:24378333]
22. Zhou G et al..  (2019)  Tyrosine nitrations impaired intracellular trafficking of FSHR to the cell surface and FSH-induced Akt-FoxO3a signaling in human granulosa cells..  Aging (Albany NY),  11  (10): (3094-3116).  [PMID:31097679]
23. Handley MT et al..  (2015)  Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation..  Open Biol,  5  (6): (150047).  [PMID:26063829]
24. Duarri A, Jezierska J, Fokkens M, Meijer M, Schelhaas HJ, den Dunnen WF, van Dijk F, Verschuuren-Bemelmans C, Hageman G, van de Vlies P et al..  (2012)  Mutations in potassium channel kcnd3 cause spinocerebellar ataxia type 19..  Ann Neurol,  72  (6): (870-80).  [PMID:23280838] [10.1021/op500134e]
25. Chih-Shia Lee,Karl J Dykema,Danielle M Hawkins,David M Cherba,Craig P Webb,Kyle A Furge,Nicholas S Duesbery.  (2011-03-03)  MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells..  PloS one,  6  ((2)): (e17165-e17165).  [PMID:21365009]
26. Lauren E Kolodziej,James P Lodolce,Jonathan E Chang,Jeffrey R Schneider,Wesley A Grimm,Sarah J Bartulis,Xiaorong Zhu,Jeannette S Messer,Stephen F Murphy,Nishith Reddy,Jerrold R Turner,David L Boone.  (2011-10-28)  TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions..  PloS one,  6  ((10)): (e26352-e26352).  [PMID:22031828]
27. Ran Kafri,Jason Levy,Miriam B Ginzberg,Seungeun Oh,Galit Lahav,Marc W Kirschner.  (2013-03-01)  Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle..  Nature,  494  ((7438)): (480-483).  [PMID:23446419]
28. V O Kaminskyy,O V Surova,T Piskunova,I B Zborovskaya,E M Tchevkina,L Andera,B Zhivotovsky.  (2013-03-09)  Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca2+/calmodulin signaling..  Cell death & disease,  4  (e522-e522).  [PMID:23470529]
29. Anne Marion Taylor,Jason Wu,Hwan-Ching Tai,Erin M Schuman.  (2013-03-29)  Axonal translation of β-catenin regulates synaptic vesicle dynamics..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  33  ((13)): (5584-5589).  [PMID:23536073]
30. Naohiko Kodo,Toshiro Matsuda,Syuichi Doi,Hiroshi Munakata.  (2013-04-03)  Salicylic acid resistance is conferred by a novel YRR1 mutation in Saccharomyces cerevisiae..  Biochemical and biophysical research communications,  434  ((1)): (42-47).  [PMID:23545261]
31. Susan E Knudson,Divya Awasthi,Kunal Kumar,Alexandra Carreau,Laurent Goullieux,Sophie Lagrange,Hélèn Vermet,Iwao Ojima,Richard A Slayden.  (2014-04-17)  A trisubstituted benzimidazole cell division inhibitor with efficacy against Mycobacterium tuberculosis..  PloS one,  9  ((4)): (e93953-e93953).  [PMID:24736743]
32. A K Gupta,K-A Nakrieko.  (2014-06-07)  Trichophyton rubrum DNA strain switching increases in patients with onychomycosis failing antifungal treatments..  The British journal of dermatology,  172  ((1)): (74-80).  [PMID:24903451]
33. Irini Tossidou,Erik Himmelseher,Beina Teng,Hermann Haller,Mario Schiffer.  (2014-06-19)  SUMOylation determines turnover and localization of nephrin at the plasma membrane..  Kidney international,  86  ((6)): (1161-1173).  [PMID:24940800]
34. Ka Tat Siu,Yanfei Xu,Kelsey L Swartz,Mitra Bhattacharyya,Sandeep Gurbuxani,Youjia Hua,Alex C Minella.  (2014-06-25)  Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation..  Molecular and cellular biology,  34  ((17)): (3244-3258).  [PMID:24958101]
35. Umut Sahin,Pierre Lapaquette,Alexandra Andrieux,Guilhem Faure,Anne Dejean.  (2014-07-19)  Sumoylation of human argonaute 2 at lysine-402 regulates its stability..  PloS one,  9  ((7)): (e102957-e102957).  [PMID:25036361]
36. Takamichi Shintani,Fusako Ohara-Waki,Akira Kitanaka,Terukazu Tanaka,Yoshitsugu Kubota.  (2014-08-03)  Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase..  Blood cells, molecules & diseases,  53  ((4)): (211-218).  [PMID:25084697]
37. Zhousheng Xiao,Jinsong Huang,Li Cao,Yingjuan Liang,Xiaobin Han,Leigh Darryl Quarles.  (2014-08-05)  Osteocyte-specific deletion of Fgfr1 suppresses FGF23..  PloS one,  9  ((8)): (e104154-e104154).  [PMID:25089825]
38. Si Hyoung Kim,Jun Goo Kang,Chul Sik Kim,Sung-Hee Ihm,Moon Gi Choi,Hyung Joon Yoo,Seong Jin Lee.  (2014-08-07)  The effect of 17-allylamino-17-demethoxygeldanamycin alone or in combination with paclitaxel on anaplastic thyroid carcinoma cells..  Endocrine,  48  ((3)): (886-893).  [PMID:25096912]
39. A Zardan,K M Nip,D Thaper,P Toren,S Vahid,E Beraldi,L Fazli,F Lamoureux,K M Gust,M E Cox,J L Bishop,A Zoubeidi.  (2014-08-19)  Lyn tyrosine kinase regulates androgen receptor expression and activity in castrate-resistant prostate cancer..  Oncogenesis,  3  (e115-e115).  [PMID:25133482]
40. Alexander Zink,Vasileios Papanagiotou,Antonia Todorova,Hans-Peter Seidl,Andrea Niedermeier,Johannes Ring,Claudia Traidl-Hoffmann.  (2014-09-02)  Outbreak of Microsporum audouinii in Munich--the return of infectious fungi in Germany..  Mycoses,  57  ((12)): (765-770).  [PMID:25175409]
41. C Kao,A Chao,C-L Tsai,W-C Chuang,W-P Huang,G-C Chen,C-Y Lin,T-H Wang,H-S Wang,C-H Lai.  (2014-11-07)  Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation..  Cell death & disease,  5  (e1510-e1510).  [PMID:25375375]
42. Katrin Kemmerer,Julia E Weigand.  (2014-12-03)  Hypoxia reduces MAX expression in endothelial cells by unproductive splicing..  FEBS letters,  588  ((24)): (4784-4790).  [PMID:25451222]
43. G Buscemi,C Ricci,L Zannini,E Fontanella,P Plevani,D Delia.  (2014-12-09)  Bimodal regulation of p21(waf1) protein as function of DNA damage levels..  Cell cycle (Georgetown, Tex.),  13  ((18)): (2901-2912).  [PMID:25486478]
44. Jen-Chung Ko,Hsien-Chun Chiu,Jhan-Jhang Syu,Chien-Yu Chen,Yun-Ting Jian,Yi-Jhen Huang,Ting-Yu Wo,Yi-Jun Jian,Po-Yuan Chang,Tai-Jing Wang,Yun-Wei Lin.  (2014-12-10)  Down-regulation of MSH2 expression by Hsp90 inhibition enhances cytotoxicity affected by tamoxifen in human lung cancer cells..  Biochemical and biophysical research communications,  456  ((1)): (506-512).  [PMID:25490383]
45. P Pierzchalski,M Jastrzebska,P Link-Lenczowski,A Leja-Szpak,J Bonior,J Jaworek,K Okon,P Wojcik.  (2015-01-03)  The dynamics of heat shock system activation in Monomac-6 cells upon Helicobacter pylori infection..  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,  65  ((6)): (791-800).  [PMID:25554983]
46. Na Liu,Peng Li,Shaolei Zang,Qiang Liu,Daoxin Ma,Xiulian Sun,Chunyan Ji.  (2015-02-04)  Novel agent nitidine chloride induces erythroid differentiation and apoptosis in CML cells through c-Myc-miRNAs axis..  PloS one,  10  ((2)): (e0116880-e0116880).  [PMID:25647305]
47. Dongnian Li,Ping Xie,Fei Zhao,Jingyi Shu,Li Li,Yutao Zhan,Lingqiang Zhang.  (2015-02-28)  F-box protein Fbxo3 targets Smurf1 ubiquitin ligase for ubiquitination and degradation..  Biochemical and biophysical research communications,  458  ((4)): (941-945).  [PMID:25721664]
48. Jonas J Staudacher,Isabel S Naarmann-de Vries,Stefanie J Ujvari,Bertram Klinger,Mumtaz Kasim,Edgar Benko,Antje Ostareck-Lederer,Dirk H Ostareck,Anja Bondke Persson,Stephan Lorenzen,Jochen C Meier,Nils Blüthgen,Pontus B Persson,Alexandra Henrion-Caude,Ralf Mrowka,Michael Fähling.  (2015-03-11)  Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum..  Nucleic acids research,  43  ((6)): (3219-3236).  [PMID:25753659]
49. Nenavath Gopal Naik,Huey-Nan Wu.  (2015-04-17)  Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication..  Journal of virology,  89  ((13)): (6746-6760).  [PMID:25878113]
50. Chi-Ting Su,Jenq-Wen Huang,Chih-Kang Chiang,Elizabeth C Lawrence,Kara L Levine,Branka Dabovic,Christine Jung,Elaine C Davis,Suneeta Madan-Khetarpal,Zsolt Urban.  (2015-04-18)  Latent transforming growth factor binding protein 4 regulates transforming growth factor beta receptor stability..  Human molecular genetics,  24  ((14)): (4024-4036).  [PMID:25882708]
51. Simone Gusenbauer,Emanuele Zanucco,Pjotr Knyazev,Axel Ullrich.  (2015-04-18)  Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell lines..  Molecular cancer,  14  (54-54).  [PMID:25884419]
52. Mario Barbosa,Isabel Prada-López,Maximiliano Álvarez,Barbas Amaral,Casares-De-Cal María de los Angeles,Inmaculada Tomás.  (2015-05-09)  Post-tooth extraction bacteraemia: a randomized clinical trial on the efficacy of chlorhexidine prophylaxis..  PloS one,  10  ((5)): (e0124249-e0124249).  [PMID:25955349]
53. Sebastian Schafer,Eleonora Adami,Matthias Heinig,Katharina E Costa Rodrigues,Franziska Kreuchwig,Jan Silhavy,Sebastiaan van Heesch,Deimante Simaite,Nikolaus Rajewsky,Edwin Cuppen,Michal Pravenec,Martin Vingron,Stuart A Cook,Norbert Hubner.  (2015-05-27)  Translational regulation shapes the molecular landscape of complex disease phenotypes..  Nature communications,  6  (7200-7200).  [PMID:26007203]
54. Bizhan Romani,Nima Shaykh Baygloo,Mohammad Reza Aghasadeghi,Elham Allahbakhshi.  (2015-06-03)  HIV-1 Vpr Protein Enhances Proteasomal Degradation of MCM10 DNA Replication Factor through the Cul4-DDB1[VprBP] E3 Ubiquitin Ligase to Induce G2/M Cell Cycle Arrest..  The Journal of biological chemistry,  290  ((28)): (17380-17389).  [PMID:26032416]
55. Sneh Lata,Amjad Ali,Vikas Sood,Rameez Raja,Akhil C Banerjea.  (2015-06-11)  HIV-1 Rev downregulates Tat expression and viral replication via modulation of NAD(P)H:quinine oxidoreductase 1 (NQO1)..  Nature communications,  6  (7244-7244).  [PMID:26059226]
56. Chunxia Zhao,Lijie Wang,Xiue Ma,Weidong Zhu,Lei Yao,Yingyu Cui,Yi Liu,Jun Li,Xingqun Liang,Yunfu Sun,Li Li,Yi-Han Chen.  (2015-06-11)  Cardiac Nav 1.5 is modulated by ubiquitin protein ligase E3 component n-recognin UBR3 and 6..  Journal of cellular and molecular medicine,  19  ((9)): (2143-2152).  [PMID:26059563]
57. Tao Tong,Nahyun Kim,Taesun Park.  (2015-06-11)  Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin..  PloS one,  10  ((6)): (e0129578-e0129578).  [PMID:26060936]
58. Leena Sathe,Cheryl Bolinger,M Amin-ul Mannan,Thomas E Dever,Madhusudan Dey.  (2015-07-16)  Evidence That Base-pairing Interaction between Intron and mRNA Leader Sequences Inhibits Initiation of HAC1 mRNA Translation in Yeast..  The Journal of biological chemistry,  290  ((36)): (21821-21832).  [PMID:26175153]
59. Jiayu Chen,Xiping Liu,Fenglin Lü,Xinping Liu,Yi Ru,Yonggang Ren,Libo Yao,Yiguo Zhang.  (2015-08-02)  Transcription factor Nrf1 is negatively regulated by its O-GlcNAcylation status..  FEBS letters,  589  ((18)): (2347-2358).  [PMID:26231763]
60. Antonis Kourtidis,Siu P Ngok,Pamela Pulimeno,Ryan W Feathers,Lomeli R Carpio,Tiffany R Baker,Jennifer M Carr,Irene K Yan,Sahra Borges,Edith A Perez,Peter Storz,John A Copland,Tushar Patel,E Aubrey Thompson,Sandra Citi,Panos Z Anastasiadis.  (2015-08-25)  Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120\xa0catenin activity..  Nature cell biology,  17  ((9)): (1145-1157).  [PMID:26302406]
61. L A Black,D P Higgins,M Govendir.  (2015-09-29)  In vitro activity of chloramphenicol, florfenicol and enrofloxacin against Chlamydia pecorum isolated from koalas (Phascolarctos cinereus)..  Australian veterinary journal,  93  ((11)): (420-423).  [PMID:26412342]
62. Satoko Arakawa,Ikuko Nakanomyo,Yoko Kudo-Sakamoto,Hiroshi Akazawa,Issei Komuro,Shigeomi Shimizu.  (2015-10-13)  Identification of a novel compound that inhibits both mitochondria-mediated necrosis and apoptosis..  Biochemical and biophysical research communications,  467  ((4)): (1006-1011).  [PMID:26456656]
63. Xin Liu,Deyan.  (2015-10-16)  Cytosolic Low Molecular Weight FGF2 Orchestrates RIG-I-Mediated Innate Immune Response..  Journal of immunology (Baltimore, Md. : 1950),  195  ((10)): (4943-4952).  [PMID:26466960]
64. Angela M Jablonski,Todd Lamitina,Nicole F Liachko,Mariangela Sabatella,Jiayin Lu,Lei Zhang,Lyle W Ostrow,Preetika Gupta,Chia-Yen Wu,Shachee Doshi,Jelena Mojsilovic-Petrovic,Hannes Lans,Jiou Wang,Brian Kraemer,Robert G Kalb.  (2015-10-23)  Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  35  ((42)): (14286-14306).  [PMID:26490867]
65. Boshi Wang,Aihui Ma,Li Zhang,Wei-Lin Jin,Yu Qian,Guiqin Xu,Bijun Qiu,Zhaojuan Yang,Yun Liu,Qiang Xia,Yongzhong Liu.  (2015-10-30)  POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation..  Nature communications,  6  (8704-8704).  [PMID:26510456]
66. Yuanlin Dong,Ancizar Betancourt,Madhu Chauhan,Meena Balakrishnan,Fernando Lugo,Matthew L Anderson,Jimmy Espinoza,Karin Fox,Michael Belfort,Chandrasekhar Yallampalli.  (2015-10-30)  Pregnancy Increases Relaxation in Human Omental Arteries to the CGRP Family of Peptides..  Biology of reproduction,  93  ((6)): (134-134).  [PMID:26510864]
67. Sarah Bertoli,Helena Boutzen,Laure David,Clément Larrue,François Vergez,Anne Fernandez-Vidal,Lingli Yuan,Marie-Anne Hospital,Jérôme Tamburini,Cécile Demur,Eric Delabesse,Estelle Saland,Jean-Emmanuel Sarry,Marie-Odile Galcera,Véronique Mansat-De Mas,Christine Didier,Christine Dozier,Christian Récher,Stéphane Manenti.  (2015-10-31)  CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia..  Oncotarget,  6  ((35)): (38061-38078).  [PMID:26515730]
68. Andreia V Mendes,Cláudia P Grou,Jorge E Azevedo,Manuel P Pinto.  (2015-11-03)  Evaluation of the activity and substrate specificity of the human SENP family of SUMO proteases..  Biochimica et biophysica acta,  1863  ((1)): (139-147).  [PMID:26522917]
69. Zhen Wei,Jinglue Song,Guanghui Wang,Ximao Cui,Jun Zheng,Yunlan Tang,Xinyuan Chen,Jixi Li,Long Cui,Chen-Ying Liu,Wei Yu.  (2018-10-28)  Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis..  Nature communications,  9  ((1)): (4468-4468).  [PMID:30367038]
70. Almudena Pacheco,Tanuja T Merianda,Jeffery L Twiss,Gianluca Gallo.  (2019-11-02)  Mechanism and role of the intra-axonal Calreticulin translation in response to axonal injury..  Experimental neurology,  323  (113072-113072).  [PMID:31669485]
71. Dimitra A Karamanou,Konstantinos A Aliferis.  (2020-05-04)  The yeast (Saccharomyces cerevisiae) YCF1 vacuole transporter: Evidence on its implication into the yeast resistance to flusilazole as revealed by GC/EI/MS metabolomics..  Pesticide biochemistry and physiology,  165  (104475-104475).  [PMID:32359550]
72. Eun Kyoung Do,Hye Ji Moon,Kyung Taek Kang,Jung Won Yoon,Ye Seul Kim,Jeong Kon Seo,Jae Ho Kim.  (2020-09-09)  Kap1 regulates the self-renewal of embryonic stem cells and cellular reprogramming by modulating Oct4 protein stability..  Cell death and differentiation,  28  ((2)): (685-699).  [PMID:32895487]
73. Alessandro De Simone,Maya N Evanitsky,Luke Hayden,Ben D Cox,Julia Wang,Valerie A Tornini,Jianhong Ou,Anna Chao,Kenneth D Poss,Stefano Di Talia.  (2021-01-08)  Control of osteoblast regeneration by a train of Erk activity waves..  Nature,  590  ((7844)): (129-133).  [PMID:33408418]
74. Jasbir Singh Dalal,Kellen Diamond Winden,Catherine Lourdes Salussolia,Maria Sundberg,Achint Singh,Truc Thanh Pham,Pingzhu Zhou,William T Pu,Meghan T Miller,Mustafa Sahin.  (2021-07-15)  Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts..  eLife,  10    [PMID:34259631]
75. Zhifang Zhao,Xinhua Li,Junfang Hao,John H Winston,Steven A Weinman.  (2007-07-27)  The ClC-3 chloride transport protein traffics through the plasma membrane via interaction of an N-terminal dileucine cluster with clathrin..  The Journal of biological chemistry,  282  ((39)): (29022-29031).  [PMID:17652080]
76. Qingyuan Yang,Chao Ou,Mei Liu,Weifan Xiao,Chuanjun Wen,Fenyong Sun.  (2014-04-09)  NRAGE promotes cell proliferation by stabilizing PCNA in a ubiquitin-proteasome pathway in esophageal carcinomas..  Carcinogenesis,  35  ((7)): (1643-1651).  [PMID:24710624]
77. Dae Hong Kim,Ik Hwan Lee,Seung Taek Nam,Ji Hong,Peng Zhang,Jae Sam Hwang,Heon Seok,Hyemin Choi,Dong Gun Lee,Jae Il Kim,Ho Kim.  (2014-05-07)  Neurotropic and neuroprotective activities of the earthworm peptide Lumbricusin..  Biochemical and biophysical research communications,  448  ((3)): (292-297).  [PMID:24796676]
78. Helaine Graziele Santos Vieira,Priscila Grynberg,Mainá Bitar,Simone da Fonseca Pires,Heron Oliveira Hilário,Andrea Mara Macedo,Carlos Renato Machado,Hélida Monteiro de Andrade,Glória Regina Franco.  (2014-05-21)  Proteomic analysis of Trypanosoma cruzi response to ionizing radiation stress..  PloS one,  9  ((5)): (e97526-e97526).  [PMID:24842666]
79. Cédric Langhi,Ángel Baldán.  (2014-11-25)  CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis..  Hepatology (Baltimore, Md.),  61  ((4)): (1227-1238).  [PMID:25418138]
80. Emily Brookes,Benoit Laurent,Katrin Õunap,Renee Carroll,John B Moeschler,Michael Field,Charles E Schwartz,Jozef Gecz,Yang Shi.  (2015-02-11)  Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity..  Human molecular genetics,  24  ((10)): (2861-2872).  [PMID:25666439]
81. Rama Ibrahim,Antoinette Lemoine,Jacques Bertoglio,Joël Raingeaud.  (2015-03-31)  Human enhancer of filamentation 1-induced colorectal cancer cell migration: Role of serine phosphorylation and interaction with the breast cancer anti-estrogen resistance 3 protein..  The international journal of biochemistry & cell biology,  64  (45-57).  [PMID:25817040]
82. Priyanka Singh,Yeon Ju Kim,Hina Singh,Chao Wang,Kyu Hyon Hwang,Mohamed El-Agamy Farh,Deok Chun Yang.  (2015-04-08)  Biosynthesis, characterization, and antimicrobial applications of silver nanoparticles..  International journal of nanomedicine,  10  (2567-2577).  [PMID:25848272]
83. Alessia Deglincerti,Yaobin Liu,Dilek Colak,Ulrich Hengst,Guoqiang Xu,Samie R Jaffrey.  (2015-04-23)  Coupled local translation and degradation regulate growth cone collapse..  Nature communications,  6  (6888-6888).  [PMID:25901863]
84. Hyun Ho Choi,Sergei Guma,Lekun Fang,Liem Phan,Cristina Ivan,Keith Baggerly,Anil Sood,Mong-Hong Lee.  (2015-05-07)  Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis..  Cell cycle (Georgetown, Tex.),  14  ((14)): (2265-2273).  [PMID:25945542]
85. Elías Barquero-Calvo,Ricardo Mora-Cartín,Vilma Arce-Gorvel,Juana L de Diego,Carlos Chacón-Díaz,Esteban Chaves-Olarte,Caterina Guzmán-Verri,Andre G Buret,Jean-Pierre Gorvel,Edgardo Moreno.  (2015-05-07)  Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide..  PLoS pathogens,  11  ((5)): (e1004853-e1004853).  [PMID:25946018]
86. Fang Fang Zhang,Norimitsu Morioka,Tomoya Kitamura,Kazue Hisaoka-Nakashima,Yoshihiro Nakata.  (2015-07-28)  Proinflammatory cytokines downregulate connexin 43-gap junctions via the ubiquitin-proteasome system in rat spinal astrocytes..  Biochemical and biophysical research communications,  464  ((4)): (1202-1208).  [PMID:26212436]
87. Alain M Guillem,Zila Martínez-Lozada,Luisa C Hernández-Kelly,Esther López-Bayghen,Bruno López-Bayghen,Oscar A Calleros,Marco R Campuzano,Arturo Ortega.  (2015-09-20)  Methylphenidate Increases Glutamate Uptake in Bergmann Glial Cells..  Neurochemical research,  40  ((11)): (2317-2324).  [PMID:26384974]
88. Yunseon Jang,Jeongsu Han,Soo Jeong Kim,Jungim Kim,Min Joung Lee,Soyeon Jeong,Min Jeong Ryu,Kang-Sik Seo,Song-Yi Choi,Minho Shong,Kyu Lim,Jun Young Heo,Gi Ryang Kweon.  (2015-10-17)  Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation..  Oncotarget,  6  ((35)): (38127-38138).  [PMID:26474388]
89. Yvonne Diener,Marion Jurk,Britta Kandil,Yeong-Hoon Choi,Stefan Wild,Ute Bissels,Andreas Bosio.  (2015-11-26)  RNA-based, transient modulation of gene expression in human haematopoietic stem and progenitor cells..  Scientific reports,  5  (17184-17184).  [PMID:26599627]
90. Furqan M Fazal,Shuo Han,Kevin R Parker,Pornchai Kaewsapsak,Jin Xu,Alistair N Boettiger,Howard Y Chang,Alice Y Ting.  (2019-06-25)  Atlas of Subcellular RNA Localization Revealed by APEX-Seq..  Cell,  178  ((2)): (473-490).  [PMID:31230715]
91. Jie-Ning Li,Hui-Lung Sun,Ming-Yang Wang,Pai-Sheng Chen.  (2021-07-23)  E-cadherin Interacts With Posttranslationally-Modified AGO2 to Enhance miRISC Activity..  Frontiers in cell and developmental biology,  9  (671244-671244).  [PMID:34291046]
92. Daohui Gong, Xueping Liu, Pengfei Wu, Yue Chen, Yuhang Xu, Zhan Gao, Hang Qian, Guansong Wang, Binfeng He.  (2024)  Rab26 alleviates sepsis-induced immunosuppression as a master regulator of macrophage ferroptosis and polarization shift.  FREE RADICAL BIOLOGY AND MEDICINE,  212  (271).  [PMID:38169213] [10.1016/j.freeradbiomed.2023.12.046]
93. Zhang Yuying, Zhang Pingping, Zhang Xin, Liu Ye.  (2023)  HH-A, a modified honokiol, protects against cerebral ischemia/reperfusion induced brain injury in rodent via Nrf2/HO-1 signaling pathways.  NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY,    (30): (1-14).  [PMID:37955691] [10.1007/s00210-023-02816-8]
94. Rui Miao, Cong Jiang, Winston Y. Chang, Haiwei Zhang, Jinsu An, Felicia Ho, Pengcheng Chen, Han Zhang, Caroline Junqueira, Dulguun Amgalan, Felix G. Liang, Junbing Zhang, Charles L. Evavold, Iva Hafner-Bratkovič, Zhibin Zhang, Pietro Fontana, Shiyu Xia, Markus Waldeck-Weiermair, Youdong Pan, Thomas Michel, Liron Bar-Peled, Hao Wu, Jonathan C. Kagan, Richard N. Kitsis, Peng Zhang, Xing Liu, Judy Lieberman.  (2023)  Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.  IMMUNITY,  56  (15): (2523-2541.e8).  [PMID:37924812] [10.1016/j.immuni.2023.10.004]
95. Xiaolin Zhang, Zhen Dong, Yuanmiao Yang, Chaolong Liu, Jisheng Li, Wenli Sun, Yikang Zhu, Yang Shen, Zhi Wang, Muhan Lü, Hongjuan Cui.  (2023)  Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,    (19):   [PMID:37870273] [10.1021/acs.jafc.3c01244]
96. Ye Jianfeng, Liu Wangmin, Yu Xueyang, Wu Lina, Chen Zhengjie, Yu Yufei, Wang Jianfeng, Bai Song, Zhang Mo.  (2023)  TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling.  Cell Death Discovery,  9  (1): (1-15).  [PMID:37845209] [10.1038/s41420-023-01675-9]
97. Xuepeng Wang, Chunchun Zou, Changju Hou, Zhenyu Bian, Wu Jiang, Maoqiang Li, Liulong Zhu.  (2023)  Extracellular vesicles from bone marrow mesenchymal stem cells alleviate osteoporosis in mice through USP7-mediated YAP1 protein stability and the Wnt/β-catenin pathway.  BIOCHEMICAL PHARMACOLOGY,  217  (115829).  [PMID:37748664] [10.1016/j.bcp.2023.115829]
98. Peng Zhu, Dongze Niu, Sainan Zhang, Chunyu Li, Dongmin Yin, Junqiang Zhi, Lili Zhang, Xingmei Jiang, Jianjun Ren.  (2024)  Enhanced delignification and production of bioactive compounds in wheat straw by optimizing sterilization methods for Irpex lacteus fermentation.  FOOD CHEMISTRY,  435  (20): (137570).  [PMID:37774616] [10.1016/j.foodchem.2023.137570]
99. Xian Lin, Tengyu Lin, Xiaocheng Wang, Jiaxin He, Xu Gao, Shuyan Lyu, Qingwen Wang, Jian Chen.  (2023)  Sesamol serves as a p53 stabilizer to relieve rheumatoid arthritis progression and inhibits the growth of synovial organoids.  PHYTOMEDICINE,  121  (8): (155109).  [PMID:37778247] [10.1016/j.phymed.2023.155109]
100. Huimin Chen, Yue Liu, Tingwei Zhang, Tongtong Huang, Yating Lang, Qinghao Sheng, Yingxiao Liu, Zhijuan Kong, Ying Gao, Shangwei Lu, Meilin Yang, Xia Li, Rong Wang, Zhimei Lv.  (2023)  Inhibition of the lncRNA 585189 prevents podocyte injury and mitochondria dysfunction by promoting hnRNP A1 and SIRT1 in diabetic nephropathy.  MOLECULAR AND CELLULAR ENDOCRINOLOGY,    (5): (112065).  [PMID:37690472] [10.1016/j.mce.2023.112065]
101. Peijun Liu, Weihua Tang, Dong Zhao, Pan Zhou, Ke Hu.  (2023)  Active metabolites and potential mechanisms of Notopterygium incisum against obstructive sleep apnea Syndrome (OSAS): network analysis and experimental assessment.  Frontiers in Pharmacology,  14  (1185100).  [PMID:37719850] [10.3389/fphar.2023.1185100]
102. Ziyuan Tong, Yuan Shen, Quan Yuan, Honghao Yu.  (2023)  HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH,  1870  (119553).  [PMID:37527738] [10.1016/j.bbamcr.2023.119553]
103. Xing Zeyu, Zhen Yanhua, Chen Jie, Du Mingyang, Li Dongdong, Liu Ruyin, Zheng Jiahe.  (2023)  KPNA2 Silencing, Regulated by E3 Ubiquitin Ligase FBXW7, Alleviates Endothelial Dysfunction and Inflammation Through Inhibiting the Nuclear Translocation of p65 and IRF3: A Possible Therapeutic Approach for Atherosclerosis.  INFLAMMATION,    (1-18).  [PMID:37432596] [10.1007/s10753-023-01863-w]
104. Yuan Qingling, Fan Yuxia, Liu Zheng, Wang Xiaoming, Jia Meng, Dong Yongqiang, Geng Zushi, Zheng Jian, Lu Xiubo.  (2023)  Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.  APOPTOSIS,    (1-17).  [PMID:37336836] [10.1007/s10495-023-01861-1]
105. Yu Li, Qian He, Chao-Yong He, Chao Cai, Zhen Chen, Jing-Zhu Duan.  (2023)  Activating transcription factor 4 drives the progression of diabetic cardiac fibrosis.  ESC Heart Failure,      [PMID:37290760] [10.1002/ehf2.14404]
106. Cheng Jian, Zhang Guizhong, Deng Tian, Liu Zhao, Zhang Mengqi, Zhang Pengchao, Adeshakin Funmilayo O., Niu Xiangyun, Yan Dehong, Wan Xiaochun, Yu Guang.  (2023)  CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.  Cell Death & Disease,  14  (5): (1-11).  [PMID:37210387] [10.1038/s41419-023-05858-1]
107. Xu Rongmei, Wan Min, Shi Xuemeng, Ma Shumin, Zhang Lina, Yi Ping, Zhang Rongying.  (2023)  A Rab10–ACAP1–Arf6 GTPases cascade modulates M4 muscarinic acetylcholine receptor trafficking and signaling.  CELLULAR AND MOLECULAR LIFE SCIENCES,  80  (4): (1-22).  [PMID:36917255] [10.1007/s00018-023-04722-x]
108. Adzraku Seyram Yao, Wang Guozhang, Cao Can, Bao Yurong, Wang Yizhou, Smith Alhaji Osman, Du Yuwei, Wang Haiyang, Li Yue, Xu Kailin, Qiao Jianlin, Ju Wen, Zeng Lingyu.  (2023)  Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.  CELLULAR & MOLECULAR BIOLOGY LETTERS,  28  (1): (1-23).  [PMID:36647012] [10.1186/s11658-022-00413-w]
109. Wu Zhuhua, Zhu Li, Nie Xinran, Wei Li, Qi Yong.  (2023)  USP15 promotes pulmonary vascular remodeling in pulmonary hypertension in a YAP1/TAZ-dependent manner.  EXPERIMENTAL AND MOLECULAR MEDICINE,  55  (1): (183-195).  [PMID:36635430] [10.1038/s12276-022-00920-y]
110. Xiaosong Wei, Beibei Wang, Zixin Wu, Xiaoming Yang, Yufeng Guo, Yang Yang, Zhiwei Fang, Chengzhi Yi, Liuhui Zhang, Xin Fan, Lirong Zhang, Dongkui Song.  (2023)  WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity.  CANCER LETTERS,  556  (216058).  [PMID:36627049] [10.1016/j.canlet.2023.216058]
111. Dingyou Wang, Yuke Ji, Rui Wang, Ke Cheng, Liang Liu, Na Wu, Qing Tang, Xu Zheng, Junxia Li, Zhilong Zhu, Qinghua Wang, Xueyan Zhang, Runbo Li, Jinjin Pan, Zheng Sui, Yuhui Yuan.  (2022)  Lycopene Ameliorates Hypoxic Pulmonary Hypertension via Suppression of Oxidative Stress.  Oxidative Medicine and Cellular Longevity,  2022  (9179427).  [PMID:] [10.1155/2022/9179427]
112. Jin-hua Fan, Min-min Xu, Li-ming Zhou, Zheng-wei Gui, Lu Huang, Xue-gang Li, Xiao-li Ye.  (2022)  Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.  PHYTOMEDICINE,  96  (153881).  [PMID:34942456] [10.1016/j.phymed.2021.153881]
113. Tingting Chen, Yichen Guo, Jinjun Shan, Jiarui Zhang, Xu Shen, Jun Guo, Xiaoguang Margaret Liu.  (2019)  Vector Analysis of Cytoskeletal Structural Tension and the Mechanisms that Underpin Spectrin-Related Forces in Pyroptosis.  ANTIOXIDANTS & REDOX SIGNALING,  30  (12): (1503-1520).  [PMID:29669427] [10.1089/ars.2017.7366]
114. Bingxiang Zhao, Sufang Gu, Yong Du, Minjie Shen, Xiangrui Liu, Youqing Shen.  (2018)  Solid lipid nanoparticles as carriers for oral delivery of hydroxysafflor yellow A.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  535  (164).  [PMID:29107614] [10.1016/j.ijpharm.2017.10.040]
115. Ji Zheng, Chao Su, Jianwen Zhou, Like Xu, Yanyun Qian, Hong Chen.  (2017)  Effects and mechanisms of ultraviolet, chlorination, and ozone disinfection on antibiotic resistance genes in secondary effluents of municipal wastewater treatment plants.  CHEMICAL ENGINEERING JOURNAL,  317  (309).  [PMID:] [10.1016/j.cej.2017.02.076]
116. Li Jianan, Cheng Weixiao, Xu Like, Jiao Yanan, Baig Shams Ali, Chen Hong.  (2016)  Occurrence and removal of antibiotics and the corresponding resistance genes in wastewater treatment plants: effluents’ influence to downstream water environment.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  23  (7): (6826-6835).  [PMID:26658782] [10.1007/s11356-015-5916-2]
117. Wan Min, Zhang Wenhua, Tian Yangli, Xu Chanjuan, Xu Tao, Liu Jianfeng, Zhang Rongying.  (2015)  Unraveling a molecular determinant for clathrin-independent internalization of the M2 muscarinic acetylcholine receptor.  Scientific Reports,  5  (1): (1-16).  [PMID:26094760] [10.1038/srep11408]
118. Li Jianan, Cheng Weixiao, Xu Like, Strong P. J., Chen Hong.  (2015)  Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  22  (6): (4587-4596).  [PMID:25323405] [10.1007/s11356-014-3665-2]

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