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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C408230-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $237.90 |
Fungal Inhibitors
Specifications & Purity | Moligand™, 10mM in DMSO |
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Biochemical and Physiological Mechanisms | Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximid |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | Information Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, In vivo
cell lines:HT29, Colo205, PC-3, MDA-MB-231 and K562 cells Concentrations: Incubation Time: Powder Purity:≥97% |
ALogP | 0.933 |
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hba_count | 3 |
HBD Count | 2 |
Rotatable Bond | 3 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Canonical SMILES | CC1CC(C)C(=O)C(C1)C(O)CC2CC(=O)NC(=O)C2 |
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Molecular Weight | 281.35 |
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Solubility | Solubility (25°C) In vitro DMSO: 53 mg/mL (79.62 mM); Water: Insoluble; Ethanol: Insoluble; |
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DMSO(mg / mL) Max Solubility | 56 |
DMSO(mM) Max Solubility | 199.04 |
Water(mg / mL) Max Solubility | 15 |
Water(mM) Max Solubility | 53.31 |
Pictogram(s) | GHS06, GHS08 |
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Signal | Danger |
Hazard Statements | H341:Suspected of causing genetic defects H411:Toxic to aquatic life with long lasting effects H300:Fatal if swallowed H360:May damage fertility or the unborn child |
Precautionary Statements | P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/... P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. P281:Use personal protective equipment as required. P270:Do not eat, drink or smoke when using this product. P202:Do not handle until all safety precautions have been read and understood. P330:Rinse mouth. |
Class | 6.1 |