Cycloheximide (NSC-185) - 10mM in DMSO, high purity , CAS No.66-81-9(DMSO)

Item Number
C408230
Grouped product items
SKUSizeAvailabilityPrice Qty
C408230-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$237.90

Fungal Inhibitors

Basic Description

Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsCycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximid
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

Information

Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo,
In vitro


In vivo


Cell Data

cell lines:HT29, Colo205, PC-3, MDA-MB-231 and K562 cells

Concentrations:

Incubation Time:

Powder Purity:≥97%

Product Properties

ALogP0.933
hba_count3
HBD Count2
Rotatable Bond3

Associated Targets(Human)

EIF4A1 Tchem Eukaryotic initiation factor 4A-I (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC2A1 Tchem Solute carrier family 2, facilitated glucose transporter member 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES CC1CC(C)C(=O)C(C1)C(O)CC2CC(=O)NC(=O)C2
Molecular Weight 281.35

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 53 mg/mL (79.62 mM); Water: Insoluble; Ethanol: Insoluble;
DMSO(mg / mL) Max Solubility56
DMSO(mM) Max Solubility199.04
Water(mg / mL) Max Solubility15
Water(mM) Max Solubility53.31

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08
Signal Danger
Hazard Statements

H341:Suspected of causing genetic defects

H411:Toxic to aquatic life with long lasting effects

H300:Fatal if swallowed

H360:May damage fertility or the unborn child

Precautionary Statements

P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/...

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P201:Obtain special instructions before use.

P308+P313:IF exposed or concerned: Get medical advice/attention.

P281:Use personal protective equipment as required.

P270:Do not eat, drink or smoke when using this product.

P202:Do not handle until all safety precautions have been read and understood.

P330:Rinse mouth.

Class 6.1

Related Documents

Solution Calculators