CYR61 Antibody - Primary antibody, specific to CCN1, Rabbit IgG
Synonyms
3CH61 antibody | CCN 1 antibody | CCN family member 1 antibody | CCN1 antibody | CYR 61 antibody | Cyr61 antibody | CYR61 protein antibody | CYR61_HUMAN antibody | Cysteine rich angiogenic inducer 61 antibody | Cysteine rich heparin binding protein 61 ant
Specifications & Purity
Validated, 1.0 mg/mL
Host species
Rabbit
Specificity
CCN1
Immunogen
A synthetic peptide derived from human CYR61.
Positive Control
WB: SK-N-SH, MDA-MB-231, HUVEC, A431, NIH/3T3 and C6 cell lysates.
Conjugation
Unconjugated
Grade
Validated
Product Description
Rabbit anti Human CYR61 Antibody, Polyclonal, could be used for WB and so on. Application WB: 1/500-1/2000 Protein Function Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Immunogen affinity purified
Form
Liquid
Concentration
1.0 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
CYR61 Antibody (Ab098631) - Western Blot All lanes: CYR61 Antibody (Ab098631) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 42 kDa Observed band size: 42 kDa Exposure time: 6.0 s