One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat
Storage Temp
Protected from light,Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Cytochalasin B is used in actin polymerization studies and cytological research. Cytochalasin B is a metabolite of the fungus Drechslera dematoidea which binds to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. As opposed to other Cytochalasins, cytochalasin A and Cytochalasin B bind to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Cytochalasin B inhibits phagocytosis by both mononuclear phagocytes and polymorphonuclear leukocytes A cell-permeable fungal toxin used in actin polymerization studies and cytological
1.Yaqi Feng, Mi Li. (2023) Micropipette-assisted atomic force microscopy for single-cell 3D manipulations and nanomechanical measurements. Nanoscale, [PMID:37526589]
2.Yuying Bai, Dawei Tian, Zhengxin Ren, Dangyang Yue, Qian Ren, Li Pei, Jun Pan. (2023) The dependences of mesenchymal stem cells commitments on the size, concentration, internalization and exposure time of Iron Oxide Nanoparticles through F-actin, Lamin A and ROS. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, [PMID:36939155]
4.Sun Xiaoxi, Huang Bing, Pan Yuping, Fang Jinhua, Wang Hefeng, Ji Yanru, Ling Yingchen, Guo Pei, Lin Jiangguo, Li Quhuan, Fang Ying, Wu Jianhua. (2022) Spatiotemporal characteristics of P-selectin-induced β2 integrin activation of human neutrophils under flow. Frontiers in Immunology, 13 [PMID:36439190]
5.Luchun Zhang, Meng Yuan, Xingwei Huang, Qianzi Cao, Shaogang Huang, Ruizhen Sun, Lei Lei. (2022) Inhibition of METTL5 improves preimplantation development of mouse somatic cell nuclear transfer embryos. REPRODUCTION, 164 (5):(221-230). [PMID:36111643]
References
1.Takahashi K et al.. (2018) In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization.. Sci Rep, 8 (15585). [PMID:30348987]
2.Wang F et al.. (2021) MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.. EMBO Rep, 22 (7):(e52006). [PMID:34096155]
3.Yaqi Feng, Mi Li. (2023) Micropipette-assisted atomic force microscopy for single-cell 3D manipulations and nanomechanical measurements. Nanoscale, [PMID:37526589]
4.Yuying Bai, Dawei Tian, Zhengxin Ren, Dangyang Yue, Qian Ren, Li Pei, Jun Pan. (2023) The dependences of mesenchymal stem cells commitments on the size, concentration, internalization and exposure time of Iron Oxide Nanoparticles through F-actin, Lamin A and ROS. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, [PMID:36939155]
6.Sun Xiaoxi, Huang Bing, Pan Yuping, Fang Jinhua, Wang Hefeng, Ji Yanru, Ling Yingchen, Guo Pei, Lin Jiangguo, Li Quhuan, Fang Ying, Wu Jianhua. (2022) Spatiotemporal characteristics of P-selectin-induced β2 integrin activation of human neutrophils under flow. Frontiers in Immunology, 13 [PMID:36439190]
7.Luchun Zhang, Meng Yuan, Xingwei Huang, Qianzi Cao, Shaogang Huang, Ruizhen Sun, Lei Lei. (2022) Inhibition of METTL5 improves preimplantation development of mouse somatic cell nuclear transfer embryos. REPRODUCTION, 164 (5):(221-230). [PMID:36111643]
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