Basic Description

Synonyms	2-[[(2R)-2-aminopropanoyl]amino]propanoic acid \| Z829938994 \| HY-N6864 \| D-alanyl-D-alanine \| DTXSID601016947 \| H-D-Ala-D-Ala-OH \| Epitope ID:141113 \| SCHEMBL476353 \| BRN 1363429 \| CHEBI:16576 \| BDBM50022571 \| (D-Ala)2 \| (R)-2-((R)-2-Aminopropanamido)prop
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	It is found in the stem termini of peptidoglycan side-chain pentapeptide found in the cell walls of gram positive bacteria. The D-ala-d-ala stem termini is the site of interaction of glycopeptide antibiotics such as vancomycin and teicoplanin. D-ala-D-ala
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	D-Ala-D-Ala is a biologically active peptide used for affinity chromatography and binding mechanism studies of antibiotics such as teicoplanin, ristocetin, and vancomycin. A biologically active peptide used for affinity chromatography and binding mechanism studies.

Associated Targets(Human)

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 Activities)

Discover Target: SLC15A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (21 Activities)

Discover Target: murF

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488195548
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488195548
IUPAC Name	(2R)-2-[[(2R)-2-aminopropanoyl]amino]propanoic acid
INCHI	InChI=1S/C6H12N2O3/c1-3(7)5(9)8-4(2)6(10)11/h3-4H,7H2,1-2H3,(H,8,9)(H,10,11)/t3-,4-/m1/s1
InChi Key	DEFJQIDDEAULHB-QWWZWVQMSA-N
Canonical SMILES	CC(C(=O)NC(C)C(=O)O)N
Isomeric SMILES	C[C@H](C(=O)N[C@H](C)C(=O)O)N
WGK Germany	3
PubChem CID	5460362
Molecular Weight	160.17

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
J1510087	Certificate of Analysis	Jun 06, 2023	A101620
B2321252	Certificate of Analysis	Mar 01, 2023	A101620
B2321251	Certificate of Analysis	Feb 28, 2023	A101620

Safety and Hazards(GHS)

WGK Germany	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Arabi Maryam, Ostovan Abbas, Wang Yunqing, Mei Rongchao, Fu Longwen, Li Jinhua, Wang Xiaoyan, Chen Lingxin. (2022) Chiral molecular imprinting-based SERS detection strategy for absolute enantiomeric discrimination. Nature Communications, 13 (1): (1-14). [PMID:36180485] [10.1038/s41467-022-33448-w]
2. Xinglong Yang, Yan Dang, Jinli Lou, Huawu Shao, Xingyu Jiang. (2018) D-alanyl-D-alanine-Modified Gold Nanoparticles Form a Broad-Spectrum Sensor for Bacteria. Theranostics, 8 (5): ( 1449–1457). [PMID:29507633] [10.7150/thno.22540]

References

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24. Delphine Patin,Julieanne Bostock,Ian Chopra,Dominique Mengin-Lecreulx,Didier Blanot. (2012-01-11) Biochemical characterisation of the chlamydial MurF ligase, and possible sequence of the chlamydial peptidoglycan pentapeptide stem.. Archives of microbiology, 194 ((6)): (505-512). [PMID:22231476]
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35. Matthew W Vetting,Nawar Al-Obaidi,Suwen Zhao,Brian San Francisco,Jungwook Kim,Daniel J Wichelecki,Jason T Bouvier,Jose O Solbiati,Hoan Vu,Xinshuai Zhang,Dmitry A Rodionov,James D Love,Brandan S Hillerich,Ronald D Seidel,Ronald J Quinn,Andrei L Osterman,John E Cronan,Matthew P Jacobson,John A Gerlt,Steven C Almo. (2014-12-30) Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.. Biochemistry, 54 ((3)): (909-931). [PMID:25540822]
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53. Xinglong Yang, Yan Dang, Jinli Lou, Huawu Shao, Xingyu Jiang. (2018) D-alanyl-D-alanine-Modified Gold Nanoparticles Form a Broad-Spectrum Sensor for Bacteria. Theranostics, 8 (5): ( 1449–1457). [PMID:29507633] [10.7150/thno.22540]

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SKU	Size	Availability	Price
A101620-250mg	250mg	In stock	$172.90
A101620-1g	1g	In stock	$472.90
A101620-5g	5g	In stock	$2,124.90

D-Ala-D-Ala - 99%, high purity , CAS No.923-16-0