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Home Chemistry & Biochemicals Reference Materials d-Bicuculline - analytical standard, high purity , CAS No.485-49-4, Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GABA A receptor α6 subunit;Channel b
d-Bicuculline - analytical standard, high purity , CAS No.485-49-4, Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GABA A receptor α6 subunit;Channel b
Basic Description Synonyms (+)-Bicuculline- Bio-X | KBio1_000609 | HB0896 | HMS501O11 | SR-01000075252 | BCP04180 | HY-N0219 | Lopac0_000234 | MLS002153892 | (6R)-6-((5S)-6-methyl(5,6,7,8-tetrahydro-2H-1,3-dioxolano[4,5-g]isoquinolin-5- yl))-6-hydro-2H-1,3-dioxoleno[4,5-e]isobenzof Specifications & Purity Moligand™, analytical standard Storage Temp Store at 2-8°C Shipped In Wet ice Grade analytical standard, Moligand™ Action Type ANTAGONIST, CHANNEL BLOCKER Mechanism of action Antagonist of GABA A receptor α1 subunit;Antagonist of GABA A receptor α2 subunit;Antagonist of GABA A receptor α3 subunit;Antagonist of GABA A receptor α4 subunit;Antagonist of GABA A receptor α5 subunit;Antagonist of GABA A receptor α6 subunit;Channel b Note 卖完停产，不再备货
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one INCHI InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 InChi Key IYGYMKDQCDOMRE-ZWKOTPCHSA-N Canonical SMILES CN1CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3 Isomeric SMILES CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3 WGK Germany 3 RTECS LV0909840 PubChem CID 10237 UN Number 1544 Molecular Weight 367.35 Beilstein 98786 Reaxy-Rn 98786
Chemical and Physical Properties Specific Rotation[α] +127.0 to +132.0 deg(C=1, CHCl3) Melt Point(°C) 195-199°C
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS09 Signal Danger Hazard Statements H311: Toxic in contact with skin
H331: Toxic if inhaled
H400: Very toxic to aquatic life
H300: Fatal if swallowed
H311+H331: Toxic in contact with skin or if inhaled.
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P391: Collect spillage.
P330: Rinse mouth.
P361+P364: Take off immediately all contaminated clothing and wash it before reuse.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P316: Get emergency medical help immediately.
WGK Germany 3 RTECS LV0909840 Reaxy-Rn 98786 Merck Index 1203
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