Specific inhibitor of alkaline ceramidase (IC 50 = 1 μM). Elevates endogenous ceramide leading to growth suppression and cell cycle arrest. Inhibits acid ceramidase (IC 50 = 500 μM). Cell-permeable. Active in vitro .
Storage Temp
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
1.Bhabak KP, Arenz C. (2012) Novel amide- and sulfonamide-based aromatic ethanolamines: effects of various substituents on the inhibition of acid and neutral ceramidases.. Bioorg Med Chem, 20 (20):(6162-70). [PMID:22989912]
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