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D(+)-Fucose - 98%, high purity , CAS No.3615-37-0

65 Citations
Item Number
F100396
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F100396-1g
1g
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$109.90
F100396-5g
5g
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$328.90
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Chemical Biology monosaccharide

Basic Description

Synonyms(2R,3S,4S,5R)-2,3,4,5-tetrahydroxyhexanal | GTPL4722 | (+)-fucose | D-Galactose, 6-deoxy- | D-FUCOSE [MI] | UNII-603I57Y449 | aldehydo-D-fucose | 603I57Y449 | CHEBI:48203 | MFCD00135603 | D-(+)-Fucose | EINECS 222-792-9 | Fucose, D- | DTXSID80883994 | SCH
Specifications & PurityMoligand™, ≥98%
Storage TempArgon charged
Shipped InNormal
GradeMoligand™
Product Description

D-(+)-Fucose is a nonmetabolizable analogue of l-arabinose. D-(+)-Fucose prevents growth of Escherichia coli B/r on a mineral salts medium plus l-arabinose by inhibiting induction of the l-arabinose operon[1]. D-fucose is a potent inducer of beta-methylgalactoside permease (MGP).

Associated Targets(Human)

FUT9 Tbio Alpha-(1,3)-fucosyltransferase 9 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FUT9 Tbio Fucosyltransferase 9 (24 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488186822
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488186822
IUPAC Name (2R,3S,4S,5R)-2,3,4,5-tetrahydroxyhexanal
INCHI InChI=1S/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m1/s1
InChi Key PNNNRSAQSRJVSB-DPYQTVNSSA-N
Canonical SMILES CC(C(C(C(C=O)O)O)O)O
Isomeric SMILES C[C@H]([C@@H]([C@@H]([C@H](C=O)O)O)O)O
WGK Germany 3
PubChem CID 94270
Molecular Weight 164.16
Beilstein 1723320
Reaxy-Rn 1723320

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
E2429364Certificate of AnalysisMay 11, 2024 F100396
E2429365Certificate of AnalysisMay 11, 2024 F100396
F2315068Certificate of AnalysisMay 22, 2023 F100396
F2315071Certificate of AnalysisMay 22, 2023 F100396
K2218686Certificate of AnalysisSep 03, 2022 F100396
K2218687Certificate of AnalysisSep 03, 2022 F100396
K2218689Certificate of AnalysisSep 03, 2022 F100396
K2218690Certificate of AnalysisSep 03, 2022 F100396
H2219473Certificate of AnalysisJul 15, 2022 F100396
H2219474Certificate of AnalysisJul 15, 2022 F100396

Chemical and Physical Properties

SensitivityMoisture sensitive.
Specific Rotation[α]75.5 ° (C=10, H2O)
Melt Point(°C)135-141°C

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 1723320
Merck Index 4278

Related Documents

 SDS

 Specification Sheet

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Citations of This Product

How to Cite Aladdin Scientific Products?
1. Kui Zhao, Xueyi Wu, Guiqi Han, Lin Sun, Changwen Zheng, Hua Hou, Ben Bin Xu, Zeinhom M. El-Bahy, Cheng Qian, Mohamed Kallel, Hassan Algadi, Zhanhu Guo, Zhengjun Shi.  (2024)  Phyllostachys nigra (Lodd. ex Lindl.) derived polysaccharide with enhanced glycolipid metabolism regulation and mice gut microbiome.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  257  (29): (128588).  [PMID:38048922] [10.1016/j.ijbiomac.2023.128588]
2. Meixia Xie, Jiale Cai, Xiaoting Zhong, Jiayin Liang, Shengwang Liang, Minghua Xian, Chunyan Yan, Shumei Wang.  (2024)  Extraction and structural profiling of polysaccharides from Rehmannia glutinosa and anti-inflammatory action via the NF-κB/IκBα pathway.  INDUSTRIAL CROPS AND PRODUCTS,  208  (117874).  [PMID:] [10.1016/j.indcrop.2023.117874]
3. Mingjing Zheng, Xin Tian, Zhipeng Li, Tao Hong, Yanbing Zhu, Yuanfan Yang, Qingbiao Li, Hui Ni, Zedong Jiang.  (2023)  Effects of ultra-high pressure assisted extraction on the structure, antioxidant and hypolipidemic activities of Porphyra haitanensis polysaccharides.  FOOD CHEMISTRY,    (23): (137856).  [PMID:37948798] [10.1016/j.foodchem.2023.137856]
4. Shuwei Yuan, Miaomiao Zhang, Zhen Yao, Jiangyun Liu, Xiang Li, Zhenqing Zhang, Duxin Li.  (2024)  Isolation, structural characterization, and bioactivities of neutral polysaccharides from Zizania latifolia.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  254  (127679).  [PMID:37890741] [10.1016/j.ijbiomac.2023.127679]
5. Qihong Jiang, Lin Chen, Rui Wang, Yin Chen, Shanggui Deng, Guoxin Shen, Shulai Liu, Xingwei Xiang.  (2024)  Hypoglycemic mechanism of Tegillarca granosa polysaccharides on type 2 diabetic mice by altering gut microbiota and regulating the PI3K-akt signaling pathway.  Food Science and Human Wellness,  13  (5): (842).  [PMID:10025403] [10.26599/FSHW.2022.9250072]
6. Huien Chen, Xinyu Liu, Meixia Xie, Xiaoting Zhong, Chunyan Yan, Minghua Xian, Shumei Wang.  (2023)  Two polysaccharides from Rehmannia glutinosa: isolation, structural characterization, and hypoglycemic activities.  RSC Advances,  13  (43): (30190-30201).  [PMID:37842674] [10.1039/D3RA05677E]
7. Ai Yuan-li, Wang Wei-jia, Liu Fan-jian, Fang Wei, Chen Hang-zi, Wu Liu-zheng, Hong Xuehui, Zhu Yuekun, Zhang Ci-xiong, Liu Long-yu, Hong Wen-bin, Zhou Bo, Chen Qi-tao, Wu Qiao.  (2023)  Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.  CELL RESEARCH,    (1-19).  [PMID:37460805] [10.1038/s41422-023-00848-6]
8. Qianni Chen, Jiaqi Fan, Lianzhu Lin, Mouming Zhao.  (2023)  Combination of Lycium barbarum L. and Laminaria japonica polysaccharides as a highly efficient prebiotic: Optimal screening and complementary regulation of gut probiotics and their metabolites.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  246  (125534).  [PMID:37355074] [10.1016/j.ijbiomac.2023.125534]
9. Yang Liu, Limei Ran, Yahong Wang, Peng Wan, Hongli Zhou.  (2023)  Basic characterization, antioxidant and immunomodulatory activities of polysaccharides from sea buckthorn leaves.  FITOTERAPIA,  169  (105592).  [PMID:37343686] [10.1016/j.fitote.2023.105592]
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12. Ruoyu Du, Weiwei Guo, Yu Shen, Jinhang Dai, Haidong Zhang, Ming Fu, Xingmin Wang.  (2023)  In situ assay of the reducing sugars in hydrophilic natural deep eutectic solvents by a modified DNS method.  JOURNAL OF MOLECULAR LIQUIDS,  385  (122286).  [PMID:] [10.1016/j.molliq.2023.122286]
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14. Saijuan Li, Fangge Wu, Pengcheng Gao, Can Jin, Yuyong Wang, Wenfeng Liao, Kan Ding.  (2023)  A novel peptidoglycan isolated from Semiaquilegia adoxoides inhibits Aβ42 production via activating autophagy.  FITOTERAPIA,    (105552).  [PMID:37257698] [10.1016/j.fitote.2023.105552]
15. Shilei Wang, Yuan Peng, Yixin Zhuang, Nan Wang, Jianchang Jin, Zhajun Zhan.  (2023)  Purification, Structural Analysis and Cardio-Protective Activity of Polysaccharides from Radix Astragali.  MOLECULES,  28  (10): (4167).  [PMID:37241906] [10.3390/molecules28104167]
16. Yaxian Chen, Yini Cai, Zhimin Zhao, Depo Yang, Xinjun Xu.  (2023)  Optimization of Extraction Process, Preliminary Characterization and Safety Study of Crude Polysaccharides from Morindae Officinalis Radix.  Foods,  12  (8): (1590).  [PMID:37107385] [10.3390/foods12081590]
17. Huan Ouyang, Baoli Guo, Yang Hu, Lijun Li, Zedong Jiang, Qingbiao Li, Hui Ni, Zhipeng Li, Mingjing Zheng.  (2023)  Effect of ultra-high pressure treatment on structural and functional properties of dietary fiber from pomelo fruitlets.  Food Bioscience,  52  (102436).  [PMID:] [10.1016/j.fbio.2023.102436]
18. Yongshuai Jing, Shilin Zhang, Feifan Wang, Beibei Hu, Shiguo Sun, Danshen Zhang, Yuguang Zheng, Lanfang Wu.  (2023)  Structure-activity relationship of antioxidant polysaccharides from Salvia miltiorrhiza based on multiple fingerprint profiles and chemometrics analysis.  LWT-FOOD SCIENCE AND TECHNOLOGY,  174  (114473).  [PMID:] [10.1016/j.lwt.2023.114473]
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20. Yajing Yang, Guoqiang Chen, Xiaoqi Zhao, Xiaohe Cao, Lei Wang, Jingjiu Mu, Fenghui Qi, Lijuan Liu, Haibo Zhang.  (2023)  Structural Characterization, Antioxidant and Antitumor Activities of the Two Novel Exopolysaccharides Produced by Debaryomyces hansenii DH-1.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (1): (335).  [PMID:36613777] [10.3390/ijms24010335]
21. Cui Cao, Lilong Wang, Xueqian Zhang, Chunqing Ai, Zhongfu Wang, Linjuan Huang, Shuang Song, Beiwei Zhu.  (2023)  Interaction between Bacteroidetes species in the fermentation of Lycium barbarum arabinogalactan.  FOOD CHEMISTRY,  409  (135288).  [PMID:36584527] [10.1016/j.foodchem.2022.135288]
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23. Zhengyu Hu, Jiaming Wang, Long Jin, Tieqiang Zong, Yuanqi Duan, Jinfeng Sun, Wei Zhou, Gao Li.  (2022)  Preparation, Characterization and Anti-Complementary Activity of Three Novel Polysaccharides from Cordyceps militaris.  Polymers,  14  (21): (4636).  [PMID:36365633] [10.3390/polym14214636]
24. Qingxia Yuan, Kunling Lv, Jinwen Huang, Shujing Sun, Ziyu Fang, Hongjie Tan, Hong Li, Dan Chen, Longyan Zhao, Chenghai Gao, Yonghong Liu.  (2022)  Simulated digestion, dynamic changes during fecal fermentation and effects on gut microbiota of Avicennia marina (Forssk.) Vierh. fruit non-starch polysaccharides.  Food Chemistry-X,  16  (100475).  [PMID:36263243] [10.1016/j.fochx.2022.100475]
25. Yalan Zhang, Liang He, Qin Li, Junwen Cheng, Yanbin Wang, Jiancheng Zhao, Shaofei Yuan, Yongjian Chen, Rui Shi.  (2022)  Optimization of ultrasonic-assisted deep eutectic solvent for the extraction of polysaccharides from Indocalamus tessellatus leaves and their biological studies.  Sustainable Chemistry and Pharmacy,  30  (100855).  [PMID:] [10.1016/j.scp.2022.100855]
26. Dongxue Cao, Enwei Wei, Zeyu Wang, Zhengyu Hu, Ling Qi, Hongli Zhou, Jingli Zhao.  (2022)  Microwave-assisted extraction, structural elucidation, and in vitro anti-glioma and immunostimulatory activity of polysaccharide from Panax ginseng C. A. Meyer.  INDUSTRIAL CROPS AND PRODUCTS,  189  (115729).  [PMID:] [10.1016/j.indcrop.2022.115729]
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28. Zhengyu Hu, Ruiying Yu, Jinfeng Sun, Yuanqi Duan, Hongli Zhou, Wei Zhou, Gao Li.  (2022)  Static decolorization of polysaccharides from the leaves of Rhododendron dauricum: Process optimization, characterization and antioxidant activities.  PROCESS BIOCHEMISTRY,  121  (113).  [PMID:] [10.1016/j.procbio.2022.06.025]
29. Meng-Ting Kuang, Jing-Yue Xu, Jin-Yu Li, Liu Yang, Bo Hou, Qi Zhao, Jiang-Miao Hu.  (2022)  Purification, structural characterization and immunomodulatory activities of a polysaccharide from the fruiting body of Morchella sextelata.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  213  (394).  [PMID:35588979] [10.1016/j.ijbiomac.2022.05.096]
30. Qiang Wei, Maochen Xing, Ke Wang, Qiong Yang, Jiarui Zhao, Yuan Wang, Xia Li, Kai Ji, Shuliang Song.  (2022)  Fucoidan Is Not Completely Dependent on Degradation to Fucose to Relieve Ulcerative Colitis.  Pharmaceuticals,  15  (4): (430).  [PMID:35455427] [10.3390/ph15040430]
31. Yanyang Gu, Liying Niu, Jiangfeng Song, Chunju Liu, Zhongyuan Zhang, Chunquan Liu, Dajing Li, Lixia Xiao.  (2022)  Effect of Pretreatment and High Hydrostatic Pressure on Soluble Dietary Fiber in Lotus Root Residues.  JOURNAL OF FOOD QUALITY,  2022  (5565538).  [PMID:] [10.1155/2022/5565538]
32. Kunfeng Zhang, Yuzhe Huang, Qianzhen Wu, Wenhua Guo, Hao Chen, Wenna Zhang, Yong Li, Yongming Lu, Qingxi Wu, Wenjuan Pan, Lei Chen, Yan Chen.  (2022)  Antibacterial effect and mechanism against Escherichia coli of polysaccharides from Armillariella tabescens mycelia.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  207  (750).  [PMID:35318079] [10.1016/j.ijbiomac.2022.03.086]
33. Hualing Xie, Jingyu Fang, Mohamed A. Farag, Zhenhao Li, Peilong Sun, Ping Shao.  (2022)  Dendrobium officinale leaf polysaccharides regulation of immune response and gut microbiota composition in cyclophosphamide-treated mice.  Food Chemistry-X,  13  (100235).  [PMID:35499019] [10.1016/j.fochx.2022.100235]
34. Shuo Shi, Guocheng Wang, Jie Liu, Sunan Liu, Qiuyu Xu, Xi Lan, Jianxing Feng, Jing Sun, Wentao Zhang, Jianlong Wang.  (2021)  Gentiana straminea Maxim. polysaccharide decolored via high-throughput graphene-based column and its anti-inflammatory activity.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  193  (1727).  [PMID:34774595] [10.1016/j.ijbiomac.2021.11.010]
35. Songze Ke, Yanlei Yu, Qiaoli Xu, Bo Zhang, Sijia Wang, Weihua Jin, Bin Wei, Hong Wang.  (2021)  Composition-Activity Relationships of Polysaccharides from Saccharina japonica in Regulating Gut Microbiota in Short-Term High-Fat Diet-Fed Mice.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  69  (37): (11121–11130).  [PMID:34498470] [10.1021/acs.jafc.1c04490]
36. Dawood Hosni Dawood, Mohamed Samir Darwish, Asmaa A. El-Awady, Azza H. Mohamed, Ahmed A. Zaki, Mohamed A. Taher.  (2021)  Chemical characterization of Cassia fistula polysaccharide (CFP) and its potential application as a prebiotic in synbiotic preparation.  RSC Advances,  11  (22): (13329-13340).  [PMID:35423880] [10.1039/D1RA00380A]
37. Yilin Zhang, Mengqi Wu, Jingrui Xi, Chen Pan, Zhizhen Xu, Wei Xia, Wenqing Zhang.  (2021)  Multiple-fingerprint analysis of Poria cocos polysaccharide by HPLC combined with chemometrics methods.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  198  (114012).  [PMID:33713882] [10.1016/j.jpba.2021.114012]
38. Guijie Chen, Yixun Bai, Ziqi Zeng, Yujia Peng, Wangting Zhou, Wenbiao Shen, Xiaoxiong Zeng, Zhonghua Liu.  (2021)  Structural Characterization and Immunostimulatory Activity of Heteropolysaccharides from Fuzhuan Brick Tea.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  69  (4): (1368–1378).  [PMID:33481588] [10.1021/acs.jafc.0c06913]
39. Weixuan Sun, Wenhan Yang, Yuxue Zheng, Huiling Zhang, Haitian Fang, Donghong Liu, Xiangli Kong, Shiguo Chen, Xingqian Ye, Jinhu Tian.  (2020)  Effect of Potato Pulp Pectic Polysaccharide on the Stability of Acidified Milk Drinks.  MOLECULES,  25  (23): (5632).  [PMID:33266001] [10.3390/molecules25235632]
40. Baolei Fan, Guoliang Wei, Xiaofeng Gan, Tingting Li, Zengyi Qu, Sheng Xu, Chao Liu, Chunqi Qian.  (2020)  Study on the varied content of Polygonatum cyrtonema polysaccharides in the processing of steaming and shining for nine times based on HPLC-MS/MS and chemometrics.  MICROCHEMICAL JOURNAL,  159  (105352).  [PMID:] [10.1016/j.microc.2020.105352]
41. Ping Ma, Congyong Sun, Wenjing Li, Wenwen Deng, Michael Adu-Frimpong, Jiangnan Yu, Ximing Xu.  (2020)  Extraction and structural analysis of Angelica sinensis polysaccharide with low molecular weight and its lipid-lowering effect on nonalcoholic fatty liver disease.  Food Science & Nutrition,  8  (7): (3212-3224).  [PMID:32724586] [10.1002/fsn3.1581]
42. Yejun Deng, Lixin Huang, Caihong Zhang, Pujun Xie, Jiang Cheng, Xiang Wang, Lujie Liu.  (2020)  Novel polysaccharide from Chaenomeles speciosa seeds: Structural characterization, α-amylase and α-glucosidase inhibitory activity evaluation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  153  (755).  [PMID:32169457] [10.1016/j.ijbiomac.2020.03.057]
43. Qingxia Yuan, Jing Zhang, Chulei Xiao, Chaligan Harqin, Mingyang Ma, Tao Long, Zhenghui Li, Yanling Yang, Jikai Liu, Longyan Zhao.  (2020)  Structural characterization of a low-molecular-weight polysaccharide from Angelica pubescens Maxim. f. biserrata Shan et Yuan root and evaluation of its antioxidant activity.  CARBOHYDRATE POLYMERS,  236  (116047).  [PMID:32172859] [10.1016/j.carbpol.2020.116047]
44. Zhenjun Zhu, Xiuping Dong, Chunhong Yan, Chunqing Ai, Dayong Zhou, Jingfeng Yang, Hui Zhang, Xiaoling Liu, Shuang Song, Hang Xiao, Beiwei Zhu.  (2019)  Structural Features and Digestive Behavior of Fucosylated Chondroitin Sulfate from Sea Cucumbers Stichopus japonicus.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  67  (37): (10534–10542).  [PMID:31464434] [10.1021/acs.jafc.9b04996]
45. Mingjia Wang, Guijie Chen, Dan Chen, Hong Ye, Yi Sun, Xiaoxiong Zeng, Zhonghua Liu.  (2019)  Purified fraction of polysaccharides from Fuzhuan brick tea modulates the composition and metabolism of gut microbiota in anaerobic fermentation in vitro.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  140  (858).  [PMID:31446105] [10.1016/j.ijbiomac.2019.08.187]
46. Ying Rui, Peng Wan, Guijie Chen, Minhao Xie, Yi Sun, Xiaoxiong Zeng, Zhonghua Liu.  (2019)  Simulated digestion and fermentation in vitro by human gut microbiota of intra- and extra-cellular polysaccharides from Aspergillus cristatus.  LWT-FOOD SCIENCE AND TECHNOLOGY,  116  (108508).  [PMID:] [10.1016/j.lwt.2019.108508]
47. Yang Cheng, Luthuli Sibusiso, Lingfeng Hou, Huijing Jiang, Peichao Chen, Xu Zhang, Mingjiang Wu, Haibin Tong.  (2019)  Sargassum fusiforme fucoidan modifies the gut microbiota during alleviation of streptozotocin-induced hyperglycemia in mice.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  131  (1162).  [PMID:30974142] [10.1016/j.ijbiomac.2019.04.040]
48. Siya Wu, Xu Zhang, Jian Liu, Jianxi Song, Ping Yu, Peichao Chen, Zhiyong Liao, Mingjiang Wu, Haibin Tong.  (2019)  Physicochemical characterization of Sargassum fusiforme fucoidan fractions and their antagonistic effect against P-selectin-mediated cell adhesion.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  133  (656).  [PMID:30930270] [10.1016/j.ijbiomac.2019.03.218]
49. Yu Ding, Yamei Yan, Yujia Peng, Dan Chen, Jia Mi, Lu Lu, Qing Luo, Xiaoying Li, Xiaoxiong Zeng, Youlong Cao.  (2019)  In vitro digestion under simulated saliva, gastric and small intestinal conditions and fermentation by human gut microbiota of polysaccharides from the fruits of Lycium barbarum.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  125  (751).  [PMID:30552927] [10.1016/j.ijbiomac.2018.12.081]
50. Qiuxuan Yang, Qilong Wang, Wenwen Deng, Congyong Sun, Qiuyu Wei, Michael Adu-Frimpong, Jixiang Shi, Jiangnan Yu, Ximing Xu.  (2019)  Anti-hyperuricemic and anti-gouty arthritis activities of polysaccharide purified from Lonicera japonica in model rats.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  123  (801).  [PMID:30445085] [10.1016/j.ijbiomac.2018.11.077]
51. Yidan Wang, Guijie Chen, Yujia Peng, Ying Rui, Xiaoxiong Zeng, Hong Ye.  (2019)  Simulated digestion and fermentation in vitro with human gut microbiota of polysaccharides from Coralline pilulifera.  LWT-FOOD SCIENCE AND TECHNOLOGY,  100  (167).  [PMID:] [10.1016/j.lwt.2018.10.028]
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