D-Galactopyranosyl-β-D-thiogalactopyranoside - ≥98%, high purity , CAS No.51555-87-4

Item Number

D343351

• Synonyms: (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyloxane-3,4,5-triol | Thiodigalactoside | Tdg cpd | D-Galactopyranosylthio-β-D-galactopyranoside | β-D-Galactopyranosyl 1-thio-β-D-galactopyranoside |
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Thiodigalactoside (TDG)is a potent inhibitor of galectin-1 (GAL1) that suppress tumor growth by inhibiting multiple cancer enhancing activities of galectin-1, including immune cell dysregulation, angiogenesis and protection against oxidative stress. Thiod
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

D-Galactopyranosyl-β- D-thiogalactopyranoside (Thiodigalactoside) is a compound belonging to the dihexoses (disaccharides containing two hexose carbohydrates). Thiodigalactoside is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core protein, and lactose permease.|D-Galactopyranosyl-β- D-thiogalactopyranoside is often used to study galectins, a family of glycan-binding lectins with diverse regulatory roles in physiological processes. Galectins have significant roles in inflammation and cancer. Thiodigalactoside is a diglycan that binds galectins-1, -3, -8, and -9 with Kd values between 24 and 78 μM. It is used to investigate the roles of these galectins in cell signaling and carcinogenesis.