Grouped product items

SKU

Size

Availability

Price

Qty

G104995-500g

500g

In stock

$39.90

Basic Description

Synonyms	SODIUM GLUCONATE\|Sodium D-gluconate\|527-07-1\|D-Gluconic acid, monosodium salt\|D-Gluconic acid sodium salt\|Monosodium gluconate\|Gluconic acid sodium salt\|gluconate sodium\|D-Gluconate sodium salt\|Gluconate (sodium)\|Monosodium D-gluconate\|D-Gluconic acid, so
Specifications & Purity	pharmaceutical grade, PharmPure™
Biochemical and Physiological Mechanisms	Gluconic acid occurs from the oxidation of glucose and is naturally in fruit, honey and wine. When used as a food additive it helps regulate acidity. It is a strong chelating agent, chelating the anions of calcium, iron, aluminum, copper, and other heavy
Storage Temp	Desiccated
Shipped In	Normal
Grade	pharmaceutical grade, PharmPure™

Associated Targets

KAT2A Tchem Histone acetyltransferase KAT2A 0 Activities

Discover Target: KAT2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Discover Target: LMNA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 0 Activities

Discover Target: NR1I2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	sodium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
INCHI	InChI=1S/C6H12O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1
InChi Key	UPMFZISCCZSDND-JJKGCWMISA-M
Canonical SMILES	C(C(C(C(C(C(=O)[O-])O)O)O)O)O.[Na+]
Isomeric SMILES	C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Na+]
WGK Germany	1
RTECS	LZ5235000
PubChem CID	23672301
Molecular Weight	218.14
Beilstein	3919651
Reaxy-Rn	3919651

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]	13 ° (C=2, H2O)
Melt Point(°C)	200-205°C

Safety and Hazards(GHS)

WGK Germany	1
RTECS	LZ5235000
Reaxy-Rn	3919651
Merck Index	4456

References

1. Anjana Gulani,Harshpal S Sachdev. (2012-04-20) Zinc supplements for preventing otitis media.. The Cochrane database of systematic reviews, 4 ((4)): (CD006639-CD006639). [PMID:22513942]
2. Michael T Rose,Terry J Rose,Juan Pariasca-Tanaka,Tadashi Yoshihashi,Heiko Neuweger,Alexander Goesmann,Michael Frei,Matthias Wissuwa. (2012-04-25) Root metabolic response of rice (Oryza sativa L.) genotypes with contrasting tolerance to zinc deficiency and bicarbonate excess.. Planta, 236 ((4)): (959-973). [PMID:22526504]
3. T Shigeta,N Matsuno,H Obara,H Mizunuma,H Kanazawa,H Tanaka,A Fukuda,S Sakamoto,M Kasahara,S Uemoto,S Enosawa. (2012-05-09) Functional recovery of donation after cardiac death liver graft by continuous machine perfusion preservation in pigs.. Transplantation proceedings, 44 ((4)): (946-947). [PMID:22564592]
4. Erika C S Oliveira,Patricia M Muller,Fernanda L M Silva,Lorena T B Nery,Marcelo J C de Sá,Maria Madalena P Guerra,Karla P Oliveira-Esquerre,John P Kastelic,Robert H Douglas. (2012-06-12) Oral administration of an anti-inflammatory does not compromise the efficacy of intra-testicular injection of zinc gluconate as a contraceptive for dogs.. Animal reproduction science, 132 ((3-4)): (207-212). [PMID:22682769]
5. Luca Rolle,Manuela Giordano,Simone Giacosa,Simone Vincenzi,Susana Río Segade,Fabrizio Torchio,Benedetta Perrone,Vincenzo Gerbi. (2012-06-13) CIELab* parameters of white dehydrated grapes as quality markers according to chemical composition, volatile profile and mechanical properties.. Analytica chimica acta, 732 (105-113). [PMID:22688041]
6. Jeffrey E Nowak,Kelli Harmon,Charles C Caldwell,Hector R Wong. (2012-07-05) Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis.. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 13 ((5)): (e323-e329). [PMID:22760431]
7. Maria Meyer,Paul Schweiger,Uwe Deppenmeier. (2012-07-14) Effects of membrane-bound glucose dehydrogenase overproduction on the respiratory chain of Gluconobacter oxydans.. Applied microbiology and biotechnology, 97 ((8)): (3457-3466). [PMID:22790543]
8. Abdelali Daddaoua,Sandy Fillet,Matilde Fernández,Zulema Udaondo,Tino Krell,Juan L Ramos. (2012-07-31) Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS.. PloS one, 7 ((7)): (e39390-e39390). [PMID:22844393]
9. Carole Poiraud,Gaëlle Quereux,Anne-Chantal Knol,Thomas Zuliani,Rémy Allix,Amir Khammari,Brigitte Dreno. (2012-08-03) Human β-defensin-2 and psoriasin, two new innate immunity targets of zinc gluconate.. European journal of dermatology : EJD, 22 ((5)): (634-639). [PMID:22854010]
10. Tobias Klein,Konstantin Schneider,Elmar Heinzle. (2012-08-14) A system of miniaturized stirred bioreactors for parallel continuous cultivation of yeast with online measurement of dissolved oxygen and off-gas.. Biotechnology and bioengineering, 110 ((2)): (535-542). [PMID:22887039]
11. Hossam E Emam,Avinash P Manian,Barbora Siroká,Thomas Bechtold. (2012-09-04) Copper inclusion in cellulose using sodium D-gluconate complexes.. Carbohydrate polymers, 90 ((3)): (1345-1352). [PMID:22939350]
12. Ubaid H Shah,Amani K Abu-Shaheen,Mohammad A Malik,Seema Alam,Muhammad Riaz,Mohamad A Al-Tannir. (2012-09-18) The efficacy of zinc supplementation in young children with acute lower respiratory infections: a randomized double-blind controlled trial.. Clinical nutrition (Edinburgh, Scotland), 32 ((2)): (193-199). [PMID:22981241]
13. Nehemiah Cox,Darrell Pilling,Richard H Gomer. (2012-10-03) NaCl potentiates human fibrocyte differentiation.. PloS one, 7 ((9)): (e45674-e45674). [PMID:23029177]
14. Óttar Rolfsson,Giuseppe Paglia,Manuela Magnusdóttir,Bernhard Ø Palsson,Ines Thiele. (2012-10-17) Inferring the metabolism of human orphan metabolites from their metabolic network context affirms human gluconokinase activity.. The Biochemical journal, 449 ((2)): (427-435). [PMID:23067238]
15. Yanshun Xu,Wenshui Xia,Qixing Jiang. (2012-10-31) Aggregation and structural changes of silver carp actomyosin as affected by mild acidification with D-gluconic acid δ-lactone.. Food chemistry, 134 ((2)): (1005-1010). [PMID:23107720]
16. L Rajendran,L K Bieniasz. (2012-11-03) Analytical expressions for the steady-state concentrations of glucose, oxygen and gluconic acid in a composite membrane for closed-loop insulin delivery.. The Journal of membrane biology, 246 ((2)): (121-129). [PMID:23117226]
17. Anja Troge,Wolfgang Scheppach,Bjoern O Schroeder,Stefan A Rund,Klaus Heuner,Jan Wehkamp,Eduard F Stange,Tobias A Oelschlaeger. (2012-11-08) More than a marine propeller--the flagellum of the probiotic Escherichia coli strain Nissle 1917 is the major adhesin mediating binding to human mucus.. International journal of medical microbiology : IJMM, 302 ((7-8)): (304-314). [PMID:23131416]
18. . (2012-12-05) [Item 232--Facial dermatoses: acne].. Annales de dermatologie et de venereologie, 139 ((11 Suppl)): (A192-A196). [PMID:23176845]
19. Masataka Narukawa,Tomoko Tsujitani,Yusuke Ueno,Kaori Nakano-Ooka,Nari Miyamoto-Kokubo,Shoko Sawano,Yukako Hayashi. (2012-12-12) Evaluation of the suppressive effect on bitter taste of gluconate.. Bioscience, biotechnology, and biochemistry, 76 ((12)): (2282-2288). [PMID:23221707]
20. Angel A Yanagihara,Ralph V Shohet. (2012-12-20) Cubozoan venom-induced cardiovascular collapse is caused by hyperkalemia and prevented by zinc gluconate in mice.. PloS one, 7 ((12)): (e51368-e51368). [PMID:23251508]
21. Graziela Ribeiro Batista,Paula Tamiao Arantes,Thomas Attin,Annette Wiegand,Carlos Rocha Torres. (2013-02-08) Effect of chemical activation of 10% carbamide peroxide gel in tooth bleaching.. The European journal of esthetic dentistry : official journal of the European Academy of Esthetic Dentistry, 8 ((1)): (104-117). [PMID:23390623]
22. R A Romanov,O A Rogachevskaia,A S Kolesnikova,A A Khokhlov,S S Kolesnikov. (2013-03-07) [Permeability of pannexin 1 channels to large anions].. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 98 ((12)): (1578-1586). [PMID:23461201]
23. Oleg A Nardid,Miroslav I Schetinskey,Yuliya V Kucherenko. (2013-03-28) Dimethyl sulfoxide at high concentrations inhibits non-selective cation channels in human erythrocytes.. General physiology and biophysics, 32 ((1)): (23-32). [PMID:23531832]
24. Volker Behrends,Thomas J Bell,Manuel Liebeke,Anne Cordes-Blauert,Syedah N Ashraf,Chandrika Nair,James E A Zlosnik,Huw D Williams,Jacob G Bundy. (2013-04-11) Metabolite profiling to characterize disease-related bacteria: gluconate excretion by Pseudomonas aeruginosa mutants and clinical isolates from cystic fibrosis patients.. The Journal of biological chemistry, 288 ((21)): (15098-15109). [PMID:23572517]
25. Chia-Ni Lin,Frederick G Strathmann. (2013-07-12) Elevated urine zinc concentration reduces the detection of methamphetamine, cocaine, THC and opiates in urine by EMIT.. Journal of analytical toxicology, 37 ((9)): (665-669). [PMID:23843421]
26. Fiona Jasson,Istvan Nagy,Anne Chantal Knol,Thomas Zuliani,Amir Khammari,Brigitte Dréno. (2013-08-21) Different strains of Propionibacterium acnes modulate differently the cutaneous innate immunity.. Experimental dermatology, 22 ((9)): (587-592). [PMID:23947673]
27. Chang-Moon Lee,Su-Jin Cheong,Eun-Mi Kim,Seok Tae Lim,Yong Yeon Jeong,Myung-Hee Sohn,Hwan-Jeong Jeong. (2013-09-21) Nonpolymeric surface-coated iron oxide nanoparticles for in vivo molecular imaging: biodegradation, biocompatibility, and multiplatform.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54 ((11)): (1974-1980). [PMID:24050935]
28. Rita Wegmüller,Fabian Tay,Christophe Zeder,Marica Brnic,Richard F Hurrell. (2013-11-22) Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide.. The Journal of nutrition, 144 ((2)): (132-136). [PMID:24259556]
29. Wei Ren,Arif Baig,S Kevin Li. (2014-04-10) Passive and iontophoretic transport of fluorides across enamel in vitro.. Journal of pharmaceutical sciences, 103 ((6)): (1692-1700). [PMID:24715598]
30. Julia Hasreiter,Lena Goldnagl,Stefan Böhm,Helmut Kubista. (2014-04-25) Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.. American journal of physiology. Cell physiology, 306 ((12)): (C1200-C1213). [PMID:24760982]
31. Matti Kannisto,Tommi Aho,Matti Karp,Ville Santala. (2014-09-07) Metabolic engineering of Acinetobacter baylyi ADP1 for improved growth on gluconate and glucose.. Applied and environmental microbiology, 80 ((22)): (7021-7027). [PMID:25192990]
32. Yihang Li,Chad H Stahl. (2014-10-17) Dietary calcium deficiency and excess both impact bone development and mesenchymal stem cell lineage priming in neonatal piglets.. The Journal of nutrition, 144 ((12)): (1935-1942). [PMID:25320190]
33. Maram Hilwi,Oshrat Dayan,Baruch I Kanner. (2014-10-24) Conformationally sensitive proximity of extracellular loops 2 and 4 of the γ-aminobutyric acid (GABA) transporter GAT-1 inferred from paired cysteine mutagenesis.. The Journal of biological chemistry, 289 ((49)): (34258-34266). [PMID:25339171]
34. Annette Ives,Johji Nomura,Fabio Martinon,Thierry Roger,Didier LeRoy,Jeffrey N Miner,Gregoire Simon,Nathalie Busso,Alexander So. (2015-03-25) Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.. Nature communications, 6 (6555-6555). [PMID:25800347]
35. F Ru,P Banovcin,M Kollarik. (2015-04-08) Acid sensitivity of the spinal dorsal root ganglia C-fiber nociceptors innervating the guinea pig esophagus.. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27 ((6)): (865-874). [PMID:25846134]
36. K Jagajjanani Rao,Santanu Paria. (2015-06-05) Mixed Phytochemicals Mediated Synthesis of Multifunctional Ag-Au-Pd Nanoparticles for Glucose Oxidation and Antimicrobial Applications.. ACS applied materials & interfaces, 7 ((25)): (14018-14025). [PMID:26043395]
37. Steven V Molinski,Saumel Ahmadi,Maurita Hung,Christine E Bear. (2015-09-20) Facilitating Structure-Function Studies of CFTR Modulator Sites with Efficiencies in Mutagenesis and Functional Screening.. Journal of biomolecular screening, 20 ((10)): (1204-1217). [PMID:26385858]
38. Dhanendra Tomar,Fabián Jaña,Zhiwei Dong,William J Quinn,Pooja Jadiya,Sarah L Breves,Cassidy C Daw,Subramanya Srikantan,Santhanam Shanmughapriya,Neeharika Nemani,Edmund Carvalho,Aparna Tripathi,Alison M Worth,Xueqian Zhang,Roshanak Razmpour,Ajay Seelam,Stephen Rhode,Anuj V Mehta,Michael Murray,Daniel Slade,Servio H Ramirez,Prashant Mishra,Glenn S Gerhard,Jeffrey Caplan,Luke Norton,Kumar Sharma,Sudarsan Rajan,Darius Balciunas,Dayanjan S Wijesinghe,Rexford S Ahima,Joseph A Baur,Muniswamy Madesh. (2019-03-28) Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation.. Cell reports, 26 ((13)): (3709-3725). [PMID:30917323]
39. Elena von Molitor,Elina Nürnberg,Torsten Ertongur-Fauth,Paul Scholz,Katja Riedel,Mathias Hafner,Rüdiger Rudolf,Tiziana Cesetti. (2020-02-06) Analysis of calcium signaling in live human Tongue cell 3D-Cultures upon tastant perfusion.. Cell calcium, 87 (102164-102164). [PMID:32014795]
40. Cyril Cheret,Marcelo Ganzella,Julia Preobraschenski,Reinhard Jahn,Gudrun Ahnert-Hilger. (2021-01-14) Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.. Cell reports, 34 ((2)): (108623-108623). [PMID:33440152]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

D-Gluconic acid sodium salt - pharmaceutical, high purity , CAS No.527-07-1