Basic Description

Synonyms	D-Gluconic acid, sodium salt (1:1) \| Gluconic acid, monosodium salt, D- \| CAS-527-07-1 \| KS-1181 \| NCGC00164076-01 \| Gluconic acid, sodium salt \| CCG-229938 \| D-Gluconate sodium salt \| SODIUM GLUCONATE [II] \| GLUCONIC ACID SODIUM SALT [MI] \| sodium (2R,3S
Specifications & Purity	pharmaceutical grade, PharmPure™
Biochemical and Physiological Mechanisms	Gluconic acid occurs from the oxidation of glucose and is naturally in fruit, honey and wine. When used as a food additive it helps regulate acidity. It is a strong chelating agent, chelating the anions of calcium, iron, aluminum, copper, and other heavy
Storage Temp	Desiccated
Shipped In	Normal
Grade	pharmaceutical grade, PharmPure™

Associated Targets(Human)

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	sodium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
INCHI	InChI=1S/C6H12O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1
InChi Key	UPMFZISCCZSDND-JJKGCWMISA-M
Canonical SMILES	C(C(C(C(C(C(=O)[O-])O)O)O)O)O.[Na+]
Isomeric SMILES	C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Na+]
WGK Germany	1
RTECS	LZ5235000
PubChem CID	23672301
Molecular Weight	218.14
Beilstein	3919651
Reaxy-Rn	3919651

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]	13 ° (C=2, H2O)
Melt Point(°C)	200-205°C

Safety and Hazards(GHS)

WGK Germany	1
RTECS	LZ5235000
Reaxy-Rn	3919651
Merck Index	4456

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yuxin Wang, Jie Wang, Zihan Liu, Songlin Zheng, Wei Lu, Zhen He. (2023) Nanocone-shaped Ni-electroplated carbon fiber composite films for electromagnetic shielding applications. Journal of Materials Research and Technology-JMR&T, 27 (4625). [PMID:22300987] [10.1016/j.jmrt.2023.10.216]
2. Jiao Chen, Jiali Cai, Feng Sha, Wenjun Sun, Xilei Lyu, Yonghui Chang, Fei Cao, Lili Zhao, Hongli Wu, Pingkai Ouyang. (2023) Chemo-enzymatic cascades producing 2,5-furandicarboxylic acid precursors viaD-gluconate “barbell oxidation” and dehydration. GREEN CHEMISTRY, 25 (18): (7126-7140). [PMID:] [10.1039/D3GC01493B]
3. Lili Yun, Meiru Kang, Yihao Shen, Junchang Feng, Guokun Yang, Jianxin Zhang, Xiaolin Meng, Xulu Chang. (2023) Dietary Bacillus velezensis R-71003 and sodium gluconate improve antioxidant capacity, immune response and resistance against Aeromonas hydrophila in common carp. FISH & SHELLFISH IMMUNOLOGY, 139 (108921). [PMID:37385461] [10.1016/j.fsi.2023.108921]
4. Ziying You, Yue Yu, Tie Hua Wang, Chenglin Wang, Ding Xiong, Yu Shi, Zhenming Wang, Ling Ye. (2023) Divalent Anion-Induced Biohydrogels with High Strength, Anti-swelling, and Bioactive Capability for Enhanced Skull Bone Regeneration. ACS Applied Materials & Interfaces, 15 (26): (31243–31255). [PMID:37350582] [10.1021/acsami.3c04729]
5. Yajie Wang, Xin Dong, Chengfeng Liu, Peng Cheng, Gilles Mailhot. (2023) Efficient Decolorization of Azo Dye Orange II in a UV-Fe3+-PMS-Oxalate System. Processes, 11 (3): (903). [PMID:] [10.3390/pr11030903]
6. Xupo Liu, Ran Wang, Ye Chen, Cuicui Zhang, Xiaofeng Li, Xihui Wang, Jingru Zhang, Xiaofei Hao. (2023) Inhibitor-regulated corrosion strategy towards synthesizing cauliflower-like amorphous RuFe-hydroxides as advanced hydrogen evolution reaction catalysts. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (9333). [PMID:] [10.1016/j.ijhydene.2022.12.040]
7. Xulu Chang, Meiru Kang, Lili Yun, Yihao Shen, Junchang Feng, Guokun Yang, Jianxin Zhang, Xiaolin Meng. (2023) Sodium gluconate increases Bacillus velezensis R-71003 growth to improve the health of the intestinal tract and growth performance in the common carp (Cyprinus carpio L.). AQUACULTURE, 563 (738980). [PMID:] [10.1016/j.aquaculture.2022.738980]
8. Xiaoqi Liu, Tianyu Li, Zhizhang Yuan, Xianfeng Li. (2022) Low-cost all-iron flow battery with high performance towards long-duration energy storage. Journal of Energy Chemistry, 73 (445). [PMID:] [10.1016/j.jechem.2022.06.041]
9. Jingbao Wang, Jingmao Zhao, Mohammad Tabish, Fan Shi, Qi Cheng, Lijun Peng. (2022) Protection of ZnMgAl coated steel corrosion by cerium gluconate in 0.05 M NaCl solution. JOURNAL OF MOLECULAR LIQUIDS, 361 (119595). [PMID:] [10.1016/j.molliq.2022.119595]
10. Huangying Wang, Junying Yan, Rong Fu, Haiyang Yan, Chenxiao Jiang, Yaoming Wang, Tongwen Xu. (2022) Bipolar Membrane Electrodialysis for Cleaner Production of Gluconic Acid: Valorization of the Regenerated Base for the Upstream Enzyme Catalysis. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 61 (22): (7634–7644). [PMID:] [10.1021/acs.iecr.1c04657]
11. Cai Jialing, Feng Jiahui, Li Jiahui, Feng Yu, Liu Fuping, He Feifang, Yu Haoqi, Zhang Zimin, Hu Yanqin, Hua Rong. (2021) Study on scale analysis and synergistic removal behavior of neutral uranium mining hydrometallurgy process. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 328 (3): (991-1000). [PMID:] [10.1007/s10967-021-07721-z]
12. Fan Luo, Zhihuan Fu, Mingjie Wang, Zhiwei Ke, Manna Wang, WenXiong Wang, Murtaza Hasan, Xugang Shu. (2021) Growth performance, tissue mineralization, antioxidant activity and immune response of oreochromis niloticus fed with conventional and gluconic acid zinc dietary supplements. AQUACULTURE NUTRITION, 27 (3): (897-907). [PMID:] [10.1111/anu.13234]
13. Chen Sun, Mingyu Zhang, Yanhong Zhao, Jianxin Pang, Ying Peng, Jiang Zheng. (2020) An LC-MS/MS- and hURAT1 cell-based approach for screening of uricosuric agents. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1159 (122336). [PMID:32905987] [10.1016/j.jchromb.2020.122336]
14. Jin Wang, Shuang Wang, Jinping Li. (2020) S-Doped three-dimensional graphene (S-3DG): a metal-free electrocatalyst for the electrochemical synthesis of ammonia under ambient conditions. DALTON TRANSACTIONS, 49 (7): (2258-2263). [PMID:32010907] [10.1039/C9DT04827H]
15. Haitao Wang, Xiaoyu Qiu, Zhuo Peng, Wei Wang, Junlei Wang, Tiansui Zhang, Lipei Jiang, Hongfang Liu. (2020) Cobalt-gluconate-derived high-density cobalt sulfides nanocrystals encapsulated within nitrogen and sulfur dual-doped micro/mesoporous carbon spheres for efficient electrocatalysis of oxygen reduction. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 561 (829). [PMID:31767397] [10.1016/j.jcis.2019.11.065]
16. Jing Tian, Xuejun Zhou, Qingping Wu, Chilin Li. (2019) Li-salt mediated Mg-rhodizonate batteries based on ultra-large cathode grains enabled by K-ion pillaring. Energy Storage Materials, 22 (218). [PMID:] [10.1016/j.ensm.2019.01.019]
17. Liu Xianxiang, Yang Yongjun, Su Shengpei, Yin Dulin. (2017) Efficient Oxidation of Glucose into Sodium Gluconate Catalyzed by Hydroxyapatite Supported Au Catalyst. CATALYSIS LETTERS, 147 (2): (383-390). [PMID:] [10.1007/s10562-016-1952-x]
18. Zhen Zou, Dinggeng He, Linli Cai, Xiaoxiao He, Kemin Wang, Xue Yang, Liling Li, Siqi Li, Xiaoya Su. (2016) Alizarin Complexone Functionalized Mesoporous Silica Nanoparticles: A Smart System Integrating Glucose-Responsive Double-Drugs Release and Real-Time Monitoring Capabilities. ACS Applied Materials & Interfaces, 8 (13): (8358–8366). [PMID:26998551] [10.1021/acsami.5b12576]
19. Qingwu Long, Guangxian Qi, Yan Wang. (2016) Evaluation of Renewable Gluconate Salts as Draw Solutes in Forward Osmosis Process. ACS Sustainable Chemistry & Engineering, 4 (1): (85–93). [PMID:] [10.1021/acssuschemeng.5b00784]
20. Jing Gao, Li Chen, Zongcheng Yan. (2015) Phase Behavior of Aqueous Biphasic Systems Composed of Ionic Liquids and Organic Salts. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 60 (3): (464–470). [PMID:] [10.1021/je500419b]

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21. Graziela Ribeiro Batista,Paula Tamiao Arantes,Thomas Attin,Annette Wiegand,Carlos Rocha Torres. (2013-02-08) Effect of chemical activation of 10% carbamide peroxide gel in tooth bleaching.. The European journal of esthetic dentistry : official journal of the European Academy of Esthetic Dentistry, 8 ((1)): (104-117). [PMID:23390623]
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38. Dhanendra Tomar,Fabián Jaña,Zhiwei Dong,William J Quinn,Pooja Jadiya,Sarah L Breves,Cassidy C Daw,Subramanya Srikantan,Santhanam Shanmughapriya,Neeharika Nemani,Edmund Carvalho,Aparna Tripathi,Alison M Worth,Xueqian Zhang,Roshanak Razmpour,Ajay Seelam,Stephen Rhode,Anuj V Mehta,Michael Murray,Daniel Slade,Servio H Ramirez,Prashant Mishra,Glenn S Gerhard,Jeffrey Caplan,Luke Norton,Kumar Sharma,Sudarsan Rajan,Darius Balciunas,Dayanjan S Wijesinghe,Rexford S Ahima,Joseph A Baur,Muniswamy Madesh. (2019-03-28) Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation.. Cell reports, 26 ((13)): (3709-3725). [PMID:30917323]
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41. Yuxin Wang, Jie Wang, Zihan Liu, Songlin Zheng, Wei Lu, Zhen He. (2023) Nanocone-shaped Ni-electroplated carbon fiber composite films for electromagnetic shielding applications. Journal of Materials Research and Technology-JMR&T, 27 (4625). [PMID:22300987] [10.1016/j.jmrt.2023.10.216]
42. Jiao Chen, Jiali Cai, Feng Sha, Wenjun Sun, Xilei Lyu, Yonghui Chang, Fei Cao, Lili Zhao, Hongli Wu, Pingkai Ouyang. (2023) Chemo-enzymatic cascades producing 2,5-furandicarboxylic acid precursors viaD-gluconate “barbell oxidation” and dehydration. GREEN CHEMISTRY, 25 (18): (7126-7140). [PMID:] [10.1039/D3GC01493B]
43. Lili Yun, Meiru Kang, Yihao Shen, Junchang Feng, Guokun Yang, Jianxin Zhang, Xiaolin Meng, Xulu Chang. (2023) Dietary Bacillus velezensis R-71003 and sodium gluconate improve antioxidant capacity, immune response and resistance against Aeromonas hydrophila in common carp. FISH & SHELLFISH IMMUNOLOGY, 139 (108921). [PMID:37385461] [10.1016/j.fsi.2023.108921]
44. Ziying You, Yue Yu, Tie Hua Wang, Chenglin Wang, Ding Xiong, Yu Shi, Zhenming Wang, Ling Ye. (2023) Divalent Anion-Induced Biohydrogels with High Strength, Anti-swelling, and Bioactive Capability for Enhanced Skull Bone Regeneration. ACS Applied Materials & Interfaces, 15 (26): (31243–31255). [PMID:37350582] [10.1021/acsami.3c04729]
45. Yajie Wang, Xin Dong, Chengfeng Liu, Peng Cheng, Gilles Mailhot. (2023) Efficient Decolorization of Azo Dye Orange II in a UV-Fe3+-PMS-Oxalate System. Processes, 11 (3): (903). [PMID:] [10.3390/pr11030903]
46. Xupo Liu, Ran Wang, Ye Chen, Cuicui Zhang, Xiaofeng Li, Xihui Wang, Jingru Zhang, Xiaofei Hao. (2023) Inhibitor-regulated corrosion strategy towards synthesizing cauliflower-like amorphous RuFe-hydroxides as advanced hydrogen evolution reaction catalysts. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 48 (9333). [PMID:] [10.1016/j.ijhydene.2022.12.040]
47. Xulu Chang, Meiru Kang, Lili Yun, Yihao Shen, Junchang Feng, Guokun Yang, Jianxin Zhang, Xiaolin Meng. (2023) Sodium gluconate increases Bacillus velezensis R-71003 growth to improve the health of the intestinal tract and growth performance in the common carp (Cyprinus carpio L.). AQUACULTURE, 563 (738980). [PMID:] [10.1016/j.aquaculture.2022.738980]
48. Xiaoqi Liu, Tianyu Li, Zhizhang Yuan, Xianfeng Li. (2022) Low-cost all-iron flow battery with high performance towards long-duration energy storage. Journal of Energy Chemistry, 73 (445). [PMID:] [10.1016/j.jechem.2022.06.041]
49. Jingbao Wang, Jingmao Zhao, Mohammad Tabish, Fan Shi, Qi Cheng, Lijun Peng. (2022) Protection of ZnMgAl coated steel corrosion by cerium gluconate in 0.05 M NaCl solution. JOURNAL OF MOLECULAR LIQUIDS, 361 (119595). [PMID:] [10.1016/j.molliq.2022.119595]
50. Huangying Wang, Junying Yan, Rong Fu, Haiyang Yan, Chenxiao Jiang, Yaoming Wang, Tongwen Xu. (2022) Bipolar Membrane Electrodialysis for Cleaner Production of Gluconic Acid: Valorization of the Regenerated Base for the Upstream Enzyme Catalysis. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 61 (22): (7634–7644). [PMID:] [10.1021/acs.iecr.1c04657]
51. Cai Jialing, Feng Jiahui, Li Jiahui, Feng Yu, Liu Fuping, He Feifang, Yu Haoqi, Zhang Zimin, Hu Yanqin, Hua Rong. (2021) Study on scale analysis and synergistic removal behavior of neutral uranium mining hydrometallurgy process. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 328 (3): (991-1000). [PMID:] [10.1007/s10967-021-07721-z]
52. Fan Luo, Zhihuan Fu, Mingjie Wang, Zhiwei Ke, Manna Wang, WenXiong Wang, Murtaza Hasan, Xugang Shu. (2021) Growth performance, tissue mineralization, antioxidant activity and immune response of oreochromis niloticus fed with conventional and gluconic acid zinc dietary supplements. AQUACULTURE NUTRITION, 27 (3): (897-907). [PMID:] [10.1111/anu.13234]
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D-Gluconic acid sodium salt - pharmaceutical, high purity , CAS No.527-07-1