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G293810-500ml

500ml

Available within 4-8 weeks(?)

$22.90

Basic Description

Synonyms	GCO \| GLUCONIC ACID [INCI] \| D-gluconic acid \| GLUCONIC ACID (MART.) \| sodium-gluconate \| E574 \| E-574 \| Pesticide Code: 000104 \| DB13180 \| D-Glukonsaeure \| Pentahydroxycaproate \| CHEBI:33198 \| GLUCONIC ACID [VANDF] \| NCGC00260293-01 \| 2,3,4,5,6-pentahydr
Specifications & Purity	24-28 wt. % in H2O
Shipped In	Normal
Note	卖完停产，不再备货
Product Description	A chemical used in glycolytic pathway studies.

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)

Discover Target: F2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

Discover Target: CHRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

Discover Target: HTR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

Discover Target: ADRA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

Discover Target: CHRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

Discover Target: DRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

Discover Target: SLC6A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

Discover Target: ADRA1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

Discover Target: OPRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD3 Tclin Dopamine D3 receptor (14368 Activities)

Discover Target: DRD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

Discover Target: SLC6A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

Discover Target: PDE3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

Discover Target: HTR2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)

Discover Target: TBXA2R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

Discover Target: PDE4A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

Discover Target: ADORA3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH3 Tclin Histamine H3 receptor (10389 Activities)

Discover Target: HRH3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

Discover Target: KDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid
INCHI	InChI=1S/C6H12O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h2-5,7-11H,1H2,(H,12,13)/t2-,3-,4+,5-/m1/s1
InChi Key	RGHNJXZEOKUKBD-SQOUGZDYSA-N
Canonical SMILES	C(C(C(C(C(C(=O)O)O)O)O)O)O
Isomeric SMILES	C([C@H]([C@H]([C@@H]([C@H](C(=O)O)O)O)O)O)O
RTECS	LZ5057100
PubChem CID	10690
UN Number	3265
Molecular Weight	196.16
Beilstein	1726055
Reaxy-Rn	1726055

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	Soluble in water.
Refractive Index	1.4161
Boil Point(°C)	102°C
Melt Point(°C)	15°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H314:Causes severe skin burns and eye damage
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
RTECS	LZ5057100
Reaxy-Rn	1726055
Merck Index	4456

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Shuqi Wang, Yingshuang Hui, Yulu Zhan, Lou Gao, Yahong Zhang, Yi Tang. (2023) Sugars as Emerging Hydrogen Donors in the Synthesis of Alditol via Catalytic Transfer Hydrogenation. ChemCatChem, 15 (18): (e202300213). [PMID:] [10.1002/cctc.202300213]
2. Pengmei Guo, Yu Liu, Xiaojia Xu, Guijin Ma, Xiaomin Hou, Yanying Fan, Mingsheng Zhang. (2021) Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells. BIOMEDICINE & PHARMACOTHERAPY, 139 (111615). [PMID:34243598] [10.1016/j.biopha.2021.111615]
3. Zehua Zhang, Shuhua Li, Dandan Sun, Ying Yang, Zhanhai Wei, Changlu Wang, Laifeng Lu. (2021) Cultivation of Rhodosporidium paludigenum in gluconic acid enhances effectiveness against Penicillium digitatum in citrus fruit. POSTHARVEST BIOLOGY AND TECHNOLOGY, 172 (111374). [PMID:] [10.1016/j.postharvbio.2020.111374]
4. Xuan Zhang, Jiawei Lin, Fang Pi, Tao Zhang, Chao Ai, Shujuan Yu. (2020) Rheological characterization of RG-I chicory root pectin extracted by hot alkali and chelators. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 164 (759). [PMID:32650011] [10.1016/j.ijbiomac.2020.07.020]
5. Yang He, Liankui Wen, Hansong Yu, Fei Zheng, Zhitong Wang, Xuanwei Xu, Hao Zhang, Yong Cao, Bixiang Wang, Baiji Chu, Jianyu Hao. (2018) Effects of high hydrostatic pressure-assisted organic acids on the copigmentation of Vitis amurensis Rupr anthocyanins. FOOD CHEMISTRY, 268 (15). [PMID:30064742] [10.1016/j.foodchem.2018.06.052]
6. Hui Chen, Zhongyin Chen, Ying Kuang, Shuang Li, Min Zhang, Jia Liu, Zhengguang Sun, Bingbing Jiang, Xueqin Chen, Cao Li. (2018) Stepwise-acid-active organic/inorganic hybrid drug delivery system for cancer therapy. COLLOIDS AND SURFACES B-BIOINTERFACES, 167 (407). [PMID:29704741] [10.1016/j.colsurfb.2018.04.038]
7. Yujuan Chen, Qian Yang, Jing Chen, Guangyue Bai, Kelei Zhuo. (2016) Interaction of gluconate-based ionic liquids with common solvents: A study of volumetric, viscosity and conductivity properties. JOURNAL OF MOLECULAR LIQUIDS, 223 (1013). [PMID:] [10.1016/j.molliq.2016.09.022]

References

1. Shuqi Wang, Yingshuang Hui, Yulu Zhan, Lou Gao, Yahong Zhang, Yi Tang. (2023) Sugars as Emerging Hydrogen Donors in the Synthesis of Alditol via Catalytic Transfer Hydrogenation. ChemCatChem, 15 (18): (e202300213). [PMID:] [10.1002/cctc.202300213]
2. Pengmei Guo, Yu Liu, Xiaojia Xu, Guijin Ma, Xiaomin Hou, Yanying Fan, Mingsheng Zhang. (2021) Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells. BIOMEDICINE & PHARMACOTHERAPY, 139 (111615). [PMID:34243598] [10.1016/j.biopha.2021.111615]
3. Zehua Zhang, Shuhua Li, Dandan Sun, Ying Yang, Zhanhai Wei, Changlu Wang, Laifeng Lu. (2021) Cultivation of Rhodosporidium paludigenum in gluconic acid enhances effectiveness against Penicillium digitatum in citrus fruit. POSTHARVEST BIOLOGY AND TECHNOLOGY, 172 (111374). [PMID:] [10.1016/j.postharvbio.2020.111374]
4. Xuan Zhang, Jiawei Lin, Fang Pi, Tao Zhang, Chao Ai, Shujuan Yu. (2020) Rheological characterization of RG-I chicory root pectin extracted by hot alkali and chelators. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 164 (759). [PMID:32650011] [10.1016/j.ijbiomac.2020.07.020]
5. Yang He, Liankui Wen, Hansong Yu, Fei Zheng, Zhitong Wang, Xuanwei Xu, Hao Zhang, Yong Cao, Bixiang Wang, Baiji Chu, Jianyu Hao. (2018) Effects of high hydrostatic pressure-assisted organic acids on the copigmentation of Vitis amurensis Rupr anthocyanins. FOOD CHEMISTRY, 268 (15). [PMID:30064742] [10.1016/j.foodchem.2018.06.052]
6. Hui Chen, Zhongyin Chen, Ying Kuang, Shuang Li, Min Zhang, Jia Liu, Zhengguang Sun, Bingbing Jiang, Xueqin Chen, Cao Li. (2018) Stepwise-acid-active organic/inorganic hybrid drug delivery system for cancer therapy. COLLOIDS AND SURFACES B-BIOINTERFACES, 167 (407). [PMID:29704741] [10.1016/j.colsurfb.2018.04.038]
7. Yujuan Chen, Qian Yang, Jing Chen, Guangyue Bai, Kelei Zhuo. (2016) Interaction of gluconate-based ionic liquids with common solvents: A study of volumetric, viscosity and conductivity properties. JOURNAL OF MOLECULAR LIQUIDS, 223 (1013). [PMID:] [10.1016/j.molliq.2016.09.022]

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D-Gluconic acid solution - 24-28 wt. % in H2O, high purity , CAS No.526-95-4