D-Glutamic acid - 98%, high purity , CAS No.6893-26-1

Item Number
G100444
Grouped product items
SKUSizeAvailabilityPrice Qty
G100444-5g
5g
In stock
$9.90
G100444-25g
25g
In stock
$11.90
G100444-50g
50g
In stock
$20.90
G100444-100g
100g
In stock
$36.90
G100444-250g
250g
In stock
$56.90
G100444-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$100.90

Endogenous, non-selective agonist. Less active enantiomer

Basic Description

Synonyms(r)-1-aminopropane-1,3-dicarboxylic acid | (2R)-2-aminopentanedioate | SR-01000597732 | CHEBI:53375 | GLUTAMIC ACID D-FORM [MI] | C00217 | D-Glutaminic acid | PDSP2_001470 | D-2-Aminoglutaric acid | delta-Glutaminate | D-Glutamic acid, >=99% (TLC) | DB025
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsExcitatory amino acid acting at NMDA receptors; less active than the L-isomer.L-isomeralso available.
Shipped InNormal
GradeMoligand™
Note1g、5g卖完停产,不再备货
Product Description

D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.


application:

D-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods.

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2D6 Tclin Cytochrome P450 2D6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2C19 Tchem Cytochrome P450 2C19 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2C9 Tchem Cytochrome P450 2C9 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC1A3 Tchem Excitatory amino acid transporter 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PKM Tchem Pyruvate kinase PKM (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA1 Tclin Carbonic anhydrase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM1 Tchem Metabotropic glutamate receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIA3 Tclin Glutamate receptor 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIK2 Tclin Glutamate receptor ionotropic, kainate 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM2 Tchem Metabotropic glutamate receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM4 Tchem Metabotropic glutamate receptor 4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM5 Tchem Metabotropic glutamate receptor 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM7 Tchem Metabotropic glutamate receptor 7 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM3 Tchem Metabotropic glutamate receptor 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM6 Tchem Metabotropic glutamate receptor 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM3 Tchem Metabotropic glutamate receptor 3 (732 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM4 Tchem Metabotropic glutamate receptor 4 (2320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM6 Tchem Metabotropic glutamate receptor 6 (361 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM1 Tchem Metabotropic glutamate receptor 1 (2309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM5 Tchem Metabotropic glutamate receptor 5 (5733 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC1A3 Tchem Excitatory amino acid transporter 1 (586 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THP-1 (11052 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Grm2 Metabotropic glutamate receptor 2 (1326 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grm7 Metabotropic glutamate receptor 7 (580 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
murI Glutamate racemase (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gria2 Glutamate receptor ionotropic, AMPA (2103 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grik1 Glutamate receptor ionotropic, kainate (722 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488182816
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488182816
IUPAC Name (2R)-2-aminopentanedioic acid
INCHI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChi Key WHUUTDBJXJRKMK-GSVOUGTGSA-N
Canonical SMILES C(CC(=O)O)C(C(=O)O)N
Isomeric SMILES C(CC(=O)O)[C@H](C(=O)O)N
WGK Germany 1
PubChem CID 23327
Molecular Weight 147.13
Beilstein 1723800
Reaxy-Rn 1723800

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

27 results found

Lot NumberCertificate TypeDateItem
L2031127Certificate of AnalysisOct 14, 2024 G100444
I2411359Certificate of AnalysisSep 02, 2024 G100444
I2411358Certificate of AnalysisSep 02, 2024 G100444
I2411357Certificate of AnalysisSep 02, 2024 G100444
I2411356Certificate of AnalysisSep 02, 2024 G100444
I2411355Certificate of AnalysisSep 02, 2024 G100444
E2411269Certificate of AnalysisMar 21, 2024 G100444
G2321382Certificate of AnalysisJun 30, 2023 G100444
G2321427Certificate of AnalysisJun 30, 2023 G100444
G2321381Certificate of AnalysisJun 30, 2023 G100444
G2321365Certificate of AnalysisJun 30, 2023 G100444
G2321358Certificate of AnalysisJun 30, 2023 G100444
G2321350Certificate of AnalysisJun 30, 2023 G100444
G2321286Certificate of AnalysisJun 30, 2023 G100444
B2309083Certificate of AnalysisJul 04, 2022 G100444
J2222325Certificate of AnalysisJul 04, 2022 G100444
J2222326Certificate of AnalysisJul 04, 2022 G100444
J2222328Certificate of AnalysisJul 04, 2022 G100444
J2222345Certificate of AnalysisJul 04, 2022 G100444
J2222354Certificate of AnalysisJul 04, 2022 G100444
J2222358Certificate of AnalysisJul 04, 2022 G100444
D2319408Certificate of AnalysisJul 04, 2022 G100444
F2218030Certificate of AnalysisJun 22, 2022 G100444
E2223106Certificate of AnalysisFeb 26, 2022 G100444
E2223104Certificate of AnalysisFeb 26, 2022 G100444
E2223103Certificate of AnalysisFeb 26, 2022 G100444
E2223102Certificate of AnalysisFeb 26, 2022 G100444

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Chemical and Physical Properties

SolubilitySoluble in water, slightly soluble in ethanol, insoluble in ether
Specific Rotation[α]-30.0 to -33.0 deg(C=5, HCl(1+5))
Melt Point(°C)200-202°C

Safety and Hazards(GHS)

WGK Germany 1
Reaxy-Rn 1723800
Merck Index 4469

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Solution Calculators