Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
S161106-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $70.90 | |
S161106-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $210.90 | |
S161106-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $759.90 | |
S161106-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,416.90 |
Synonyms | (D)-(-)-Lactic acid | (R)-lactate | (R)-2-Hydroxypropionate | D-2-Hydroxypropionic acid | D-(-)-Lactate | D-LACTIC ACID [WHO-DD] | AS-19478 | HY-111095 | (R)-2-Hydroxypropionic acid(R)-2-Hydroxypropionic acid | (R)-alpha-Hydroxypropionate | D-Lactic acid |
---|---|
Specifications & Purity | Moligand™, ≥90%(T) |
Biochemical and Physiological Mechanisms | In animals, lactic acid is a metabolic compound produced by proliferating cells and during anaerobic conditions such as strenuous exercise. Lactic acid can be oxidized back to pyruvate or converted to glucose via gluconeogenesis. Lactic acid is preferenti |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of HCA 1 receptor |
Product Description | Lactic acid is used as a reagent in organic synthesis (in the manufacture of adhesives). It is used in the leather, textile, and tanning industries. It may be used as a plasticizer, a catalyst, or an acidifying agent. Lactic acid has even been used as a flavoring agent in the manufacture of tobacco products. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|
IUPAC Name | (2R)-2-hydroxypropanoic acid |
---|---|
INCHI | InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m1/s1 |
InChi Key | JVTAAEKCZFNVCJ-UWTATZPHSA-N |
Canonical SMILES | CC(C(=O)O)O |
Isomeric SMILES | C[C@H](C(=O)O)O |
PubChem CID | 61503 |
Molecular Weight | 90.08 |
Reaxy-Rn | 1720252 |
PubChem CID | 61503 |
---|---|
DrugBank Ligand | DB03066 |
ChEBI | CHEBI:42111 |
CAS Registry No. | 10326-41-7 |
ChEMBL Ligand | CHEMBL358850 |
RCSB PDB Ligand | LAC |
GPCRdb Ligand | D-lactic acid |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F2404014 | Certificate of Analysis | Jul 05, 2023 | S161106 |
G2326283 | Certificate of Analysis | Jul 05, 2023 | S161106 |
G2326562 | Certificate of Analysis | Jul 05, 2023 | S161106 |
G2326585 | Certificate of Analysis | Jul 05, 2023 | S161106 |
G2326589 | Certificate of Analysis | Jul 05, 2023 | S161106 |
G2326594 | Certificate of Analysis | Jul 05, 2023 | S161106 |
F2307328 | Certificate of Analysis | Jun 24, 2022 | S161106 |
G2213380 | Certificate of Analysis | Jun 24, 2022 | S161106 |
G2213382 | Certificate of Analysis | Jun 24, 2022 | S161106 |
G2213383 | Certificate of Analysis | Jun 24, 2022 | S161106 |
Solubility | Soluble in water (50mg/ml) |
---|---|
Sensitivity | heat sensitive |
Refractive Index | 1.43 |
Specific Rotation[α] | 13° (C=2.5,1.5mol/L NaOH) |
Flash Point(°C) | 110 °C |
Pictogram(s) | GHS05, GHS07 |
---|---|
Signal | Danger |
Hazard Statements | H315:Causes skin irritation H318:Causes serious eye damage |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. |
Reaxy-Rn | 1720252 |
Merck Index | 5335 |
1. Rongxiu Qin, Haiyan Chen, Rusi Wen, Guiqing Li, Zhonglei Meng. (2023) Effect of Boric Acid on the Ionization Equilibrium of α-Hydroxy Carboxylic Acids and the Study of Its Applications. MOLECULES, 28 (12): (4723). [PMID:37375278] [10.3390/molecules28124723] |
2. Xiao Zheng, Ying Liu, Yiqiong Liu, Tingting Zhang, Yuge Zhao, Jie Zang, Yan Yang, Ruiqing He, Gaowei Chong, Shuangrong Ruan, Dailin Xu, Yongyong Li, Haiqing Dong. (2022) Dual Closed-Loop of Catalyzed Lactate Depletion and Immune Response to Potentiate Photothermal Immunotherapy. ACS Applied Materials & Interfaces, 14 (20): (23260–23276). [PMID:35578899] [10.1021/acsami.2c07254] |
3. Jie Sun, Yaping Wang, Zhenguo Gao, Junbo Gong, Weiwei Tang. (2022) Additive-assisted preferential crystallization of racemic component: A case of norvaline. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 110 (206). [PMID:] [10.1016/j.jiec.2022.02.054] |
4. Jianjian Zhao, Aiyou Hao, Pengyao Xing. (2021) Enhancing Optical Activities of Benzimidazole Derivatives through Coassembly for High-Efficiency Synthesis of Chiroptical Nanomaterials and Accurate ee % Detection of Natural Acids. ACS Applied Materials & Interfaces, 13 (5): (6830–6843). [PMID:33502861] [10.1021/acsami.0c20735] |
5. Kaiyang Ma, Xiao Ding, Qiqi Song, Zhitao Han, Hang Yao, Jianhua Ding, Gang Hu. (2020) Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes. NEUROPHARMACOLOGY, 171 (108084). [PMID:32294462] [10.1016/j.neuropharm.2020.108084] |
6. Shengli Mi, Jingjing Xia, Yuanyuan Xu, Zhichang Du, Wei Sun. (2019) An integrated microchannel biosensor platform to analyse low density lactate metabolism in HepG2 cells in vitro. RSC Advances, 9 (16): (9006-9013). [PMID:35517697] [10.1039/C9RA00694J] |
7. Ai-Ling Hu, Yin-Huan Liu, Hao-Hua Deng, Guo-Lin Hong, Ai-Lin Liu, Xin-Hua Lin, Xing-Hua Xia, Wei Chen. (2014) Fluorescent hydrogen peroxide sensor based on cupric oxide nanoparticles and its application for glucose and l-lactate detection. BIOSENSORS & BIOELECTRONICS, 61 (374). [PMID:24912038] [10.1016/j.bios.2014.05.048] |
1. Rongxiu Qin, Haiyan Chen, Rusi Wen, Guiqing Li, Zhonglei Meng. (2023) Effect of Boric Acid on the Ionization Equilibrium of α-Hydroxy Carboxylic Acids and the Study of Its Applications. MOLECULES, 28 (12): (4723). [PMID:37375278] [10.3390/molecules28124723] |
2. Xiao Zheng, Ying Liu, Yiqiong Liu, Tingting Zhang, Yuge Zhao, Jie Zang, Yan Yang, Ruiqing He, Gaowei Chong, Shuangrong Ruan, Dailin Xu, Yongyong Li, Haiqing Dong. (2022) Dual Closed-Loop of Catalyzed Lactate Depletion and Immune Response to Potentiate Photothermal Immunotherapy. ACS Applied Materials & Interfaces, 14 (20): (23260–23276). [PMID:35578899] [10.1021/acsami.2c07254] |
3. Jie Sun, Yaping Wang, Zhenguo Gao, Junbo Gong, Weiwei Tang. (2022) Additive-assisted preferential crystallization of racemic component: A case of norvaline. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 110 (206). [PMID:] [10.1016/j.jiec.2022.02.054] |
4. Jianjian Zhao, Aiyou Hao, Pengyao Xing. (2021) Enhancing Optical Activities of Benzimidazole Derivatives through Coassembly for High-Efficiency Synthesis of Chiroptical Nanomaterials and Accurate ee % Detection of Natural Acids. ACS Applied Materials & Interfaces, 13 (5): (6830–6843). [PMID:33502861] [10.1021/acsami.0c20735] |
5. Kaiyang Ma, Xiao Ding, Qiqi Song, Zhitao Han, Hang Yao, Jianhua Ding, Gang Hu. (2020) Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes. NEUROPHARMACOLOGY, 171 (108084). [PMID:32294462] [10.1016/j.neuropharm.2020.108084] |
6. Shengli Mi, Jingjing Xia, Yuanyuan Xu, Zhichang Du, Wei Sun. (2019) An integrated microchannel biosensor platform to analyse low density lactate metabolism in HepG2 cells in vitro. RSC Advances, 9 (16): (9006-9013). [PMID:35517697] [10.1039/C9RA00694J] |
7. Ai-Ling Hu, Yin-Huan Liu, Hao-Hua Deng, Guo-Lin Hong, Ai-Lin Liu, Xin-Hua Lin, Xing-Hua Xia, Wei Chen. (2014) Fluorescent hydrogen peroxide sensor based on cupric oxide nanoparticles and its application for glucose and l-lactate detection. BIOSENSORS & BIOELECTRONICS, 61 (374). [PMID:24912038] [10.1016/j.bios.2014.05.048] |