Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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D422906-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Cell-permeable chemiluminescent luciferase substrate
Synonyms | D-Luciferin | 2591-17-5 | Firefly luciferin | Luciferin | (S)-2-(6-Hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid | D-(-)-Luciferin | Photinus luciferin | (S)-4,5-Dihydro-2-(6-hydroxybenzothiazol-2-yl)thiazole-4-carboxylic acid | (4S)-2-(6-hydroxy-1,3 |
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Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | Cell-permeable chemiluminescent luciferase substrate. Emits lights upon oxidative decarboxylation in the presence of ATP. Provides a bioluminescent signal for cellular ATP levels in vivo. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | D-luciferin is the natural substrate of luciferases that catalyze the production of light in bioluminescent insects. |
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IUPAC Name | (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid |
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INCHI | InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1 |
InChi Key | BJGNCJDXODQBOB-SSDOTTSWSA-N |
Canonical SMILES | C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)O |
Isomeric SMILES | C1[C@@H](N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)O |
WGK Germany | 3 |
PubChem CID | 92934 |
Molecular Weight | 280.32 |
Beilstein | 27(4)8934 |
Reaxy-Rn | 30484 |
Enter Lot Number to search for COA:
Sensitivity | heat & light &air sensitive |
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Specific Rotation[α] | -33° (C=1,DMF) |
Melt Point(°C) | 200°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Reaxy-Rn | 30484 |
Merck Index | 4086 |
1. Zhiqian Wang, Mingcong Fan, Kanza Hannachi, Yan Li, Haifeng Qian, Li Wang. (2023) Impact of red kidney bean protein on starch digestion and exploring its underlying mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (26): (127023). [PMID:37751820] |
2. Ruining Li, Zhiwei Li, Chenxi Huang, Yifeng Ding, Jia Wang, Xiaohong Wang. (2023) Phage-Based Biosensing for Rapid and Specific Detection of Staphylococcus aureus. Microorganisms, 11 (8): (2098). [PMID:37630658] |
3. Zhilin Pan, Baolin Ge, Mingjun Wei, Jeevithan Elango, Wenhui Wu. (2023) Isolation and Biochemical Properties of Type II Collagen from Blue Shark (Prionace glauca) Cartilage. Marine Drugs, 21 (5): (260). [PMID:37233454] |
4. Xinning Yu, Tengjing Xu, Huimin Shi, Jianqiao Hong, Xiaoqiang Jin, Le Cao, Jiajie Wang, Yunting Lin, Zongyou Pan, Siheng Wang, Jinghua Fang, Kaiwang Xu, Hongyun Song, Zhuxing Zhou, Sunan Zhu, Jun Yin, Yiying Qi, Xuesong Dai. (2023) Cartilage-targeting mRNA-lipid nanoparticles rescue perifocal apoptotic chondrocytes for integrative cartilage repair. CHEMICAL ENGINEERING JOURNAL, 465 (142841). [PMID:] |
5. Li Liang, Weiliang Sun, Xiaoxuan Wei, Li Wang, Huaqiang Ruan, Junchuan Zhang, Suyan Li, Bi Zhao, Mengshi Li, Zhengwen Cai, Jie'an Huang. (2023) Oxymatrine suppresses colorectal cancer progression by inhibiting NLRP3 inflammasome activation through mitophagy induction in vitro and in vivo. PHYTOTHERAPY RESEARCH, [PMID:36974424] |
6. Xuehui Wang, Jiaying Wang, Zihui An, Aifen Yang, Mengsheng Qiu, Zhou Tan. (2023) CircXPO1 Promotes Glioblastoma Malignancy by Sponging miR-7-5p. Cells, 12 (6): (831). [PMID:36980172] |
7. Hongwei Cao, Qilong Huang, Junru shi, Xiao Guan, Hongdong Song, Yu Zhang, Jian Xie, Yong Fang. (2023) Effect of conventional and microwave heating treatment on antioxidant activity of quinoa protein after simulated gastrointestinal digestion. FOOD CHEMISTRY, 415 (135763). [PMID:36870208] |
8. Xiaoyu Du, Shanyu Zhang, Liying Wang, Yuqin Wang, Pingping Fan, Wendong Jia, Panke Zhang, Shuo Huang. (2023) Single-Molecule Interconversion between Chiral Configurations of Boronate Esters Observed in a Nanoreactor. ACS Nano, 17 (3): (2881–2892). [PMID:36655995] |
9. Juan Qiao, Qian Ma, Yuying Song, Li Qi. (2022) In Situ Monitoring of Intracellular ATP Variation Based on a Thermoregulated Polymer Nanocomposite. ACS Applied Bio Materials, 5 (12): (5826–5831). [PMID:36441583] |
10. Wanyi Dong, Xinyue Zhang, Lixian Ding, Cong Liu, Minhui Ai, Yongguo Jin, Kazuhiro Isobe, Akihiro Handa, Zhaoxia Cai. (2023) Enhancement of emulsification properties by modulation of egg white protein fibril structure with different heating times. FOOD HYDROCOLLOIDS, 135 (108203). [PMID:] |
11. Henghui Zhang, Zhijun Zhang, Dongliang He, Shuying Li, Yongping Xu. (2022) Optimization of Enzymatic Hydrolysis of Perilla Meal Protein for Hydrolysate with High Hydrolysis Degree and Antioxidant Activity. MOLECULES, 27 (3): (1079). [PMID:35164344] |
1. Zhiqian Wang, Mingcong Fan, Kanza Hannachi, Yan Li, Haifeng Qian, Li Wang. (2023) Impact of red kidney bean protein on starch digestion and exploring its underlying mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (26): (127023). [PMID:37751820] |
2. Ruining Li, Zhiwei Li, Chenxi Huang, Yifeng Ding, Jia Wang, Xiaohong Wang. (2023) Phage-Based Biosensing for Rapid and Specific Detection of Staphylococcus aureus. Microorganisms, 11 (8): (2098). [PMID:37630658] |
3. Zhilin Pan, Baolin Ge, Mingjun Wei, Jeevithan Elango, Wenhui Wu. (2023) Isolation and Biochemical Properties of Type II Collagen from Blue Shark (Prionace glauca) Cartilage. Marine Drugs, 21 (5): (260). [PMID:37233454] |
4. Xinning Yu, Tengjing Xu, Huimin Shi, Jianqiao Hong, Xiaoqiang Jin, Le Cao, Jiajie Wang, Yunting Lin, Zongyou Pan, Siheng Wang, Jinghua Fang, Kaiwang Xu, Hongyun Song, Zhuxing Zhou, Sunan Zhu, Jun Yin, Yiying Qi, Xuesong Dai. (2023) Cartilage-targeting mRNA-lipid nanoparticles rescue perifocal apoptotic chondrocytes for integrative cartilage repair. CHEMICAL ENGINEERING JOURNAL, 465 (142841). [PMID:] |
5. Li Liang, Weiliang Sun, Xiaoxuan Wei, Li Wang, Huaqiang Ruan, Junchuan Zhang, Suyan Li, Bi Zhao, Mengshi Li, Zhengwen Cai, Jie'an Huang. (2023) Oxymatrine suppresses colorectal cancer progression by inhibiting NLRP3 inflammasome activation through mitophagy induction in vitro and in vivo. PHYTOTHERAPY RESEARCH, [PMID:36974424] |
6. Xuehui Wang, Jiaying Wang, Zihui An, Aifen Yang, Mengsheng Qiu, Zhou Tan. (2023) CircXPO1 Promotes Glioblastoma Malignancy by Sponging miR-7-5p. Cells, 12 (6): (831). [PMID:36980172] |
7. Hongwei Cao, Qilong Huang, Junru shi, Xiao Guan, Hongdong Song, Yu Zhang, Jian Xie, Yong Fang. (2023) Effect of conventional and microwave heating treatment on antioxidant activity of quinoa protein after simulated gastrointestinal digestion. FOOD CHEMISTRY, 415 (135763). [PMID:36870208] |
8. Xiaoyu Du, Shanyu Zhang, Liying Wang, Yuqin Wang, Pingping Fan, Wendong Jia, Panke Zhang, Shuo Huang. (2023) Single-Molecule Interconversion between Chiral Configurations of Boronate Esters Observed in a Nanoreactor. ACS Nano, 17 (3): (2881–2892). [PMID:36655995] |
9. Juan Qiao, Qian Ma, Yuying Song, Li Qi. (2022) In Situ Monitoring of Intracellular ATP Variation Based on a Thermoregulated Polymer Nanocomposite. ACS Applied Bio Materials, 5 (12): (5826–5831). [PMID:36441583] |
10. Wanyi Dong, Xinyue Zhang, Lixian Ding, Cong Liu, Minhui Ai, Yongguo Jin, Kazuhiro Isobe, Akihiro Handa, Zhaoxia Cai. (2023) Enhancement of emulsification properties by modulation of egg white protein fibril structure with different heating times. FOOD HYDROCOLLOIDS, 135 (108203). [PMID:] |
11. Henghui Zhang, Zhijun Zhang, Dongliang He, Shuying Li, Yongping Xu. (2022) Optimization of Enzymatic Hydrolysis of Perilla Meal Protein for Hydrolysate with High Hydrolysis Degree and Antioxidant Activity. MOLECULES, 27 (3): (1079). [PMID:35164344] |