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D-NMAPPD , CAS No.35922-06-6

CAS#: 35922-06-6
Formula: C₂₃H₃₈N₂O₅
Molecular Weight: 422.56
PubChem CID: 10070893

Item Number

D343063

Grouped product items
SKU	Size	Availability	Price
D343063-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$34.90
D343063-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$115.90
D343063-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$273.90
D343063-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,187.90

a potent Acid Ceramidase inhibitor that induces apoptosis.

Basic Description

Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	D-NMAPPD is an Acid Ceramidase (ceramidase) inhibitor, which acts to keep ceramide concentrations low and maintain cell viability in normal cells. The inhibition of Acid Ceramidase (ceramidase) in both non-cancerous and malignant cells leads to apoptosis. D-NMAPPD is a potent Acid Ceramidase (ceramidase) inhibitor that induces apoptosis.

Associated Targets(Human)

HL-60 (67320 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDA-MB-231 (73002 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ASAH1 Tchem Acid ceramidase (411 Activities)

Discover Target: ASAH1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ASAH2 Tchem Neutral ceramidase (95 Activities)

Discover Target: ASAH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACER1 Tbio Alkaline ceramidase 1 (5 Activities)

Discover Target: ACER1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]tetradecanamide
INCHI	InChI=1S/C23H38N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22(27)24-21(18-26)23(28)19-14-16-20(17-15-19)25(29)30/h14-17,21,23,26,28H,2-13,18H2,1H3,(H,24,27)/t21-,23-/m1/s1
InChi Key	XUSDVLHKNBOGJY-FYYLOGMGSA-N
Canonical SMILES	CCCCCCCCCCCCCC(=O)NC(CO)C(C1=CC=C(C=C1)[N+](=O)[O-])O
Isomeric SMILES	CCCCCCCCCCCCCC(=O)N[C@H](CO)[C@@H](C1=CC=C(C=C1)[N+](=O)[O-])O
PubChem CID	10070893
Molecular Weight	422.56

Solubility

Soluble in water (0.3 mg/mL at 25° C), ethanol (~20 mg/mL), DMSO (~10 mg/mL), DMF (~10 mg/mL), and Ethanol: PBS (pH 7.2) (1: 2) (~0.3 mg/mL).

Refractive Index

n20D1.53 (Predicted)

Boil Point(°C)

~636.2° C at 760 mmHg (Predicted)

Melt Point(°C)

261.57° C (Predicted)

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D-NMAPPD , CAS No.35922-06-6

Basic Description

Product Properties

Associated Targets(Human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

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