Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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D129210-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $57.90 | |
D129210-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $260.90 | |
D129210-1g | 1g | In stock | $938.90 | |
D129210-5g | 5g | In stock | $4,224.90 |
Synthetic progesterone analog
Synonyms | Levonorgestrelum | (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one | 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one | alpha-Norgestrel | FH-122A | Monovar | NORGE |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | Synthetic progesterone analog; binds to the progesterone receptor (relative binding affinities are < 0.02, 7.5, 17, 58 and 323 % for estrogen receptors, glucocorticoid receptors, mineralocorticoid receptors, androgen receptors and progesterone receptors r |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Progesterone receptor agonist |
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IUPAC Name | (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one |
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INCHI | InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1 |
InChi Key | WWYNJERNGUHSAO-XUDSTZEESA-N |
Canonical SMILES | CCC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34 |
Isomeric SMILES | CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34 |
WGK Germany | 3 |
RTECS | JF8259000 |
PubChem CID | 13109 |
Molecular Weight | 312.45 |
DrugBank Ligand | DB00367 |
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PubChem CID | 13109 |
ChEMBL Ligand | CHEMBL1389 |
Wikipedia | Levonorgestrel |
CAS Registry No. | 797-63-7 |
RCSB PDB Ligand | NOG |
PEP | levonorgestrel |
DrugCentral Ligand | 1572, 1572 |
Enter Lot Number to search for COA:
Solubility | Solvent:DMSO, Max Conc. mg/mL: 31.25, Max Conc. mM: 100 |
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Sensitivity | heat sensitive |
Specific Rotation[α] | [α]D:-34~-31° (C=1,CHCl3) |
Melt Point(°C) | 236℃ |
Pictogram(s) | GHS08, GHS09 |
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Signal | Danger |
Hazard Statements | H351:Suspected of causing cancer H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects H360:May damage fertility or the unborn child H362:May cause harm to breast-fed children |
Precautionary Statements | P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
WGK Germany | 3 |
RTECS | JF8259000 |
1. Qiuye Jin, Qiong Duan, Dingyu Ji, Jie Chang, Zhaomin Tang. (2023) Reaction mechanism, degradation pathway and toxicity assessment of NH4+ enhanced potassium ferrate removal of levofloxacin. PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 180 (16): (725). [PMID:16698035] [10.1016/j.psep.2023.10.037] |
2. Guangli Li, Xuan Wan, Yonghui Xia, Du Tuo, Xiaoman Qi, Tianyu Wang, Mohammad Mehmandoust, Nevin Erk, Quanguo He, Qing Li. (2023) Lamellar α-Zirconium Phosphate Nanoparticles Supported on N-Doped Graphene Nanosheets as Electrocatalysts for the Detection of Levofloxacin. ACS Applied Nano Materials, 6 (18): (17040–17052). [PMID:11485546] [10.1021/acsanm.3c03162] |
3. Tingting Li, Guoqiang Guo, Haoming Xing, Siyuan Tang, Houwen Hu, Linfan Wang, Xiaoqing Qian, Da Chen. (2023) Construction of fluorescent sensor array and three-dimensional microfluidic paper based analytical device for specific identification and visual determination of antibiotics in food. FOOD CHEMISTRY, 429 (136947). [PMID:37499515] [10.1016/j.foodchem.2023.136947] |
4. Donghui Wang, Yu-e Shi, Zhen Zhang, Song Shen, Zhenguang Wang. (2023) Modulating Emission of Organic Emitters from Fluorescence to Red Afterglow through Boric Acid-Assisted Energy Transfer. Journal of Physical Chemistry C, 127 (1): (682–688). [PMID:] [10.1021/acs.jpcc.2c07138] |
5. Anhua Jiang, Xinwen Huang, Geshan Zhang, Wanquan Yang. (2022) A Study of the Degradation of LEV by Transparent PVA/NCD-TiO2 Nanocomposite Films with Enhanced Visible-Light Photocatalytic Activity. Catalysts, 12 (11): (1336). [PMID:] [10.3390/catal12111336] |
6. Qinyue Wu, Yan Zhang, He Liu, Hongbo Liu, Jia Tao, Min-Hua Cui, Zhiyong Zheng, Donghui Wen, Xinmin Zhan. (2022) FexN produced in pharmaceutical sludge biochar by endogenous Fe and exogenous N doping to enhance peroxymonosulfate activation for levofloxacin degradation. WATER RESEARCH, 224 (119022). [PMID:36099758] [10.1016/j.watres.2022.119022] |
7. Xiang-Yu Zheng, Hai-Chen Zhang, Yu-Dan Lv, Feng-Yan Jin, Xiu-Juan Wu, Jie Zhu, Yang Ruan. (2022) Levetiracetam alleviates cognitive decline in Alzheimer's disease animal model by ameliorating the dysfunction of the neuronal network.. Frontiers in Aging Neuroscience, 14 (888784-888784). [PMID:36092803] [10.3389/fnagi.2022.888784] |
8. Yichen Zhang, Shugui Hua, Xiaoqin Sun, Zhuoyue Liu, Yuan Dang, Liang Zhang, Yuanzhen Zhou. (2021) A novel electrochemical cathode based on sea urchin-like NiO/Co3O4 composite inducing efficient Fenton-like process for levofloxacin degradation. APPLIED CATALYSIS A-GENERAL, 628 (118403). [PMID:] [10.1016/j.apcata.2021.118403] |
9. Yafeng Jin, Guangri Xu, Xiaobo Li, Jingjing Ma, Li Yang, Yuanchao Li, Huan Zhang, Zhen Zhang, Donghao Yao, Donghao Li. (2021) Fast cathodic reduction electrodeposition of a binder-free cobalt-doped Ni-MOF film for directly sensing of levofloxacin. JOURNAL OF ALLOYS AND COMPOUNDS, 851 (156823). [PMID:] [10.1016/j.jallcom.2020.156823] |
10. Huikai Shao, Haibo Zhou, Tingting Zhang, Xianglong Zhao, Zhengjin Jiang, Qiqin Wang. (2019) Preparation of molecularly imprinted hybrid monoliths for the selective detection of fluoroquinolones in infant formula powders. JOURNAL OF CHROMATOGRAPHY A, 1588 (33). [PMID:30587346] [10.1016/j.chroma.2018.12.038] |
11. Liu Chaoqiao, Xie Dong, Liu Peng, Xie Shilei, Wang Shoushan, Cheng Faliang, Zhang Min, Wang Lishi. (2019) Voltammetric determination of levofloxacin using silver nanoparticles deposited on a thin nickel oxide porous film. MICROCHIMICA ACTA, 186 (1): (1-10). [PMID:30554349] [10.1007/s00604-018-3146-2] |
1. Qiuye Jin, Qiong Duan, Dingyu Ji, Jie Chang, Zhaomin Tang. (2023) Reaction mechanism, degradation pathway and toxicity assessment of NH4+ enhanced potassium ferrate removal of levofloxacin. PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 180 (16): (725). [PMID:16698035] [10.1016/j.psep.2023.10.037] |
2. Guangli Li, Xuan Wan, Yonghui Xia, Du Tuo, Xiaoman Qi, Tianyu Wang, Mohammad Mehmandoust, Nevin Erk, Quanguo He, Qing Li. (2023) Lamellar α-Zirconium Phosphate Nanoparticles Supported on N-Doped Graphene Nanosheets as Electrocatalysts for the Detection of Levofloxacin. ACS Applied Nano Materials, 6 (18): (17040–17052). [PMID:11485546] [10.1021/acsanm.3c03162] |
3. Tingting Li, Guoqiang Guo, Haoming Xing, Siyuan Tang, Houwen Hu, Linfan Wang, Xiaoqing Qian, Da Chen. (2023) Construction of fluorescent sensor array and three-dimensional microfluidic paper based analytical device for specific identification and visual determination of antibiotics in food. FOOD CHEMISTRY, 429 (136947). [PMID:37499515] [10.1016/j.foodchem.2023.136947] |
4. Donghui Wang, Yu-e Shi, Zhen Zhang, Song Shen, Zhenguang Wang. (2023) Modulating Emission of Organic Emitters from Fluorescence to Red Afterglow through Boric Acid-Assisted Energy Transfer. Journal of Physical Chemistry C, 127 (1): (682–688). [PMID:] [10.1021/acs.jpcc.2c07138] |
5. Anhua Jiang, Xinwen Huang, Geshan Zhang, Wanquan Yang. (2022) A Study of the Degradation of LEV by Transparent PVA/NCD-TiO2 Nanocomposite Films with Enhanced Visible-Light Photocatalytic Activity. Catalysts, 12 (11): (1336). [PMID:] [10.3390/catal12111336] |
6. Qinyue Wu, Yan Zhang, He Liu, Hongbo Liu, Jia Tao, Min-Hua Cui, Zhiyong Zheng, Donghui Wen, Xinmin Zhan. (2022) FexN produced in pharmaceutical sludge biochar by endogenous Fe and exogenous N doping to enhance peroxymonosulfate activation for levofloxacin degradation. WATER RESEARCH, 224 (119022). [PMID:36099758] [10.1016/j.watres.2022.119022] |
7. Xiang-Yu Zheng, Hai-Chen Zhang, Yu-Dan Lv, Feng-Yan Jin, Xiu-Juan Wu, Jie Zhu, Yang Ruan. (2022) Levetiracetam alleviates cognitive decline in Alzheimer's disease animal model by ameliorating the dysfunction of the neuronal network.. Frontiers in Aging Neuroscience, 14 (888784-888784). [PMID:36092803] [10.3389/fnagi.2022.888784] |
8. Yichen Zhang, Shugui Hua, Xiaoqin Sun, Zhuoyue Liu, Yuan Dang, Liang Zhang, Yuanzhen Zhou. (2021) A novel electrochemical cathode based on sea urchin-like NiO/Co3O4 composite inducing efficient Fenton-like process for levofloxacin degradation. APPLIED CATALYSIS A-GENERAL, 628 (118403). [PMID:] [10.1016/j.apcata.2021.118403] |
9. Yafeng Jin, Guangri Xu, Xiaobo Li, Jingjing Ma, Li Yang, Yuanchao Li, Huan Zhang, Zhen Zhang, Donghao Yao, Donghao Li. (2021) Fast cathodic reduction electrodeposition of a binder-free cobalt-doped Ni-MOF film for directly sensing of levofloxacin. JOURNAL OF ALLOYS AND COMPOUNDS, 851 (156823). [PMID:] [10.1016/j.jallcom.2020.156823] |
10. Huikai Shao, Haibo Zhou, Tingting Zhang, Xianglong Zhao, Zhengjin Jiang, Qiqin Wang. (2019) Preparation of molecularly imprinted hybrid monoliths for the selective detection of fluoroquinolones in infant formula powders. JOURNAL OF CHROMATOGRAPHY A, 1588 (33). [PMID:30587346] [10.1016/j.chroma.2018.12.038] |
11. Liu Chaoqiao, Xie Dong, Liu Peng, Xie Shilei, Wang Shoushan, Cheng Faliang, Zhang Min, Wang Lishi. (2019) Voltammetric determination of levofloxacin using silver nanoparticles deposited on a thin nickel oxide porous film. MICROCHIMICA ACTA, 186 (1): (1-10). [PMID:30554349] [10.1007/s00604-018-3146-2] |