Basic Description

Synonyms	D-Penicillamine \| penicillamine \| 52-67-5 \| D-(-)-Penicillamine \| Cuprimine \| 3-Mercapto-D-valine \| Depen \| D-Penamine \| (2S)-2-Amino-3-methyl-3-sulfanylbutanoic acid \| Artamine \| Cuprenil \| D-Valine, 3-mercapto- \| D-Mercaptovaline \| (-)-Penicillamine \| Mercaptovaline \| Penicillamin \| C
Specifications & Purity	Moligand™, 10mM in Water
Biochemical and Physiological Mechanisms	Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between p
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Penicillamine is an exogenous NOS modulator, found to inhibit urease activity. It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.

Product Properties

ALogP	-1.8

Associated Targets(Human)

CTH Tchem Cystathionine gamma-lyase (0 Activities)

Discover Target: CTH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A2 Tchem Cytochrome P450 1A2 (0 Activities)

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor (0 Activities)

Discover Target: DRD2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD4 Tchem D(4) dopamine receptor (0 Activities)

Discover Target: DRD4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 (0 Activities)

Discover Target: ERBB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 (0 Activities)

Discover Target: GABRA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ELANE Tclin Neutrophil elastase (0 Activities)

Discover Target: ELANE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EGFR Tclin Epidermal growth factor receptor (0 Activities)

Discover Target: EGFR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor (0 Activities)

Discover Target: AVPR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase (0 Activities)

Discover Target: HMGCR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 (0 Activities)

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor (0 Activities)

Discover Target: HRH1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)

Discover Target: SLCO1B3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter (0 Activities)

Discover Target: SLC6A3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter (0 Activities)

Discover Target: SLC6A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (0 Activities)

Discover Target: SIGMAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 (0 Activities)

Discover Target: PTGS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 (0 Activities)

Discover Target: CA2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor (0 Activities)

Discover Target: DRD3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDR Tclin Vascular endothelial growth factor receptor 2 (0 Activities)

Discover Target: KDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 (0 Activities)

Discover Target: CHRM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM4 Tclin Muscarinic acetylcholine receptor M4 (0 Activities)

Discover Target: CHRM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor (0 Activities)

Discover Target: ADRA2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor (0 Activities)

Discover Target: ADRA2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)

Discover Target: APEX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A (0 Activities)

Discover Target: HTR2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a (0 Activities)

Discover Target: ADORA2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (0 Activities)

Discover Target: ACHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor (0 Activities)

Discover Target: ADRA1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor (0 Activities)

Discover Target: AR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A (0 Activities)

Discover Target: MAOA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AKR1B1 Tclin Aldose reductase (0 Activities)

Discover Target: AKR1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 (0 Activities)

Discover Target: ADORA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A (0 Activities)

Discover Target: HTR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 (0 Activities)

Discover Target: ADORA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 (0 Activities)

Discover Target: HTR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B (0 Activities)

Discover Target: HTR2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

F2 Tclin Prothrombin (0 Activities)

Discover Target: F2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EDNRA Tclin Endothelin-1 receptor (0 Activities)

Discover Target: EDNRA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (0 Activities)

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor (0 Activities)

Discover Target: OPRD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor (0 Activities)

Discover Target: OPRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor (0 Activities)

Discover Target: OPRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)

Discover Target: NOS2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TACR1 Tclin Substance-P receptor (0 Activities)

Discover Target: TACR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS1 Tchem Nitric oxide synthase, brain (0 Activities)

Discover Target: NOS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE5A Tclin Phosphodiesterase 5A (5113 Activities)

Discover Target: PDE5A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)

Discover Target: EGFR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

F2 Tclin Thrombin (11687 Activities)

Discover Target: F2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA2 Tclin Carbonic anhydrase II (17698 Activities)

Discover Target: CA2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HMGCR Tclin HMG-CoA reductase (2475 Activities)

Discover Target: HMGCR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

INSR Tclin Insulin receptor (5558 Activities)

Discover Target: INSR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)

Discover Target: ADRB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

Discover Target: CHRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)

Discover Target: ADRB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

Discover Target: HTR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

Discover Target: ADRA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

Discover Target: CHRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACE Tclin Angiotensin-converting enzyme (1423 Activities)

Discover Target: ACE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD2 Tclin Dopamine D2 receptor (23596 Activities)

Discover Target: DRD2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

Discover Target: DRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD4 Tchem Dopamine D4 receptor (7907 Activities)

Discover Target: DRD4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH2 Tclin Histamine H2 receptor (5428 Activities)

Discover Target: HRH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)

Discover Target: ADRA1D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOB Tclin Monoamine oxidase B (8835 Activities)

Discover Target: MAOB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)

Discover Target: HTR1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

Discover Target: HTR2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)

Discover Target: HTR2C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

Discover Target: ADORA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CALCR Tclin Calcitonin receptor (2215 Activities)

Discover Target: CALCR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

Discover Target: SLC6A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

Discover Target: ADRA1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

Discover Target: PTGS2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH1 Tclin Histamine H1 receptor (7573 Activities)

Discover Target: HRH1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)

Discover Target: ADRA1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

Discover Target: OPRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD3 Tclin Dopamine D3 receptor (14368 Activities)

Discover Target: DRD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)

Discover Target: AVPR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRD1 Tclin Delta opioid receptor (15096 Activities)

Discover Target: OPRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRK1 Tclin Kappa opioid receptor (16155 Activities)

Discover Target: OPRK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

Discover Target: SLC6A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)

Discover Target: HTR4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

Discover Target: PDE3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR2 Tclin Estrogen receptor beta (9272 Activities)

Discover Target: ESR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)

Discover Target: CYSLTR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)

Discover Target: Agtr2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mc4r Melanocortin receptor 4 (1205 Activities)

Discover Target: Mc4r

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ltc4s Leukotriene C4 synthase (1 Activities)

Discover Target: Ltc4s

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Sigmar1 Sigma opioid receptor (160 Activities)

Discover Target: Sigmar1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Npy1r Neuropeptide Y receptor type 1 (8 Activities)

Discover Target: Npy1r

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cckar Cholecystokinin A receptor (90 Activities)

Discover Target: Cckar

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nos2 Nitric oxide synthase, inducible (3573 Activities)

Discover Target: Nos2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp9 Matrix metalloproteinase 9 (38 Activities)

Discover Target: Mmp9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus subtilis (32866 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus thuringiensis (718 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasma (328 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

dapE Succinyl-diaminopimelate desuccinylase (42 Activities)

Discover Target: dapE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)

Discover Target: fba

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

spt Serine palmitoyltransferase (15 Activities)

Discover Target: spt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Glra2 Glycine receptor (1745 Activities)

Discover Target: Glra2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
INCHI	InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1
InChi Key	VVNCNSJFMMFHPL-VKHMYHEASA-N
Canonical SMILES	CC(C)(C(C(=O)O)N)S
Isomeric SMILES	CC(C)([C@H](C(=O)O)N)S
WGK Germany	2
RTECS	YV9425000
PubChem CID	5852
Molecular Weight	149.21
Beilstein	1722375
Reaxy-Rn	1722375

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Sensitivity	Heat sensitive
Refractive Index	1.53
Specific Rotation[α]	-63o
Boil Point(°C)	251.8° C
Melt Point(°C)	210°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	2
RTECS	YV9425000
Reaxy-Rn	1722375
Merck Index	7088

Citations of This Product

1. Jing Fu, Yujin Miao, Di Zhang, Yongjie Zhang, Luyao Meng, Xinrui Ni, Jinglin Shen, Wei Qi. (2023) Polymer-Enabled Assembly of Au Nanoclusters with Luminescence Enhancement and Macroscopic Chirality. LANGMUIR, 39 (37): (13316–13324). [PMID:37682809]
2. Sen Hu, Yuning Jiang, Jiaying Cao, Qiangting Zheng, Yiping Wu, Xiaoyu Guo, Ye Ying, Xinling Liu, Ying Wen, Haifeng Yang. (2023) Gold nanoparticles decorated MoS2 nanosheets for sensing and degradation of carbamazepine in environmental wastewater. Environmental Technology & Innovation, 32 (103302). [PMID:]
3. Yarong Gu, Yuchao Du, Wenhe Wang, Xiaosheng Fang, Ziqing Li, Lijuan Zhao. (2023) Enantioselective inorganic nanomaterials with near-infrared circular-polarized-activated photothermal response. CHEMICAL ENGINEERING JOURNAL, 472 (144873). [PMID:]
4. Cheng Zhang, Mengna Liang, Congying Shao, Ziwei Li, Xue Cao, Yongxiang Wang, Yanan Wu, Shun Lu. (2023) Visual Detection and Sensing of Mercury Ions and Glutathione Using Fluorescent Copper Nanoclusters. ACS Applied Bio Materials, 6 (3): (1283–1293). [PMID:36788220]
5. Xun Zhou, Juerui Zhang, Dongyan Huang, Yinhui Yi, Kechen Wu, Gangbing Zhu. (2023) Nitrogen-doped Ti3C2 MXene quantum dots as an effective FRET ratio fluorometric probe for sensitive detection of Cu2+ and D-PA. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 293 (122484). [PMID:36796242]
6. Wang Siqi, Jin Yao, Ai Wenhui, Wang Xiufeng, Zhang Zhiqing, Zhou Ting, Zhang Guodong, Wang Fang. (2023) H2O2 actuated molybdenum oxide nanodots: Multi-enzyme-like activities, leverage of Fenton reaction, and dual-mode sensitive detection of alendronate sodium. Nano Research, 16 (10): (12106-12115). [PMID:]
7. Mengna Liang, Congying Shao, Qian Zhang, Cheng Zhang, Yongxiang Wang, Xingqun Zheng, Shun Lu. (2023) High-Performance Formaldehyde Sensing Using Paper-Based Fluorescent Copper Nanoclusters. IEEE SENSORS JOURNAL, 23 (3): (2076-2084). [PMID:]
8. Weihua Yu, Jianhua Kuang, Qingqing Hu, Zhonghua Wang, Yunwen Liao, Zhengjun Cheng. (2022) Ratiometric Detection of Al Based on the Mixing of D-penicillamine-Functionalized Copper Nanoclusters with Pyridoxal 5’-phosphate. ChemistrySelect, 7 (45): (e202203721). [PMID:]
9. Hongyu Chen, Fengshou Tian, Chao Lu. (2022) Engineering Plasmon-Enhanced Fluorescent Gold Nanoclusters Using Bovine Serum Albumin as a Novel Separation Layer for Improved Selectivity. ANALYTICAL CHEMISTRY, 94 (47): (16461–16469). [PMID:36383051]
10. Xun Sun, Xinyu Zhang, Hui Yan, Hongfei Wu, Shijian Cao, Wenchen Zhao, Ting Dong, An Zhou. (2023) Protective effect of curcumin on hepatolenticular degeneration through copper excretion and inhibition of ferroptosis. PHYTOMEDICINE, 113 (154539). [PMID:36898256]
11. Lianming Zhang, Kui Luo, Jingxia Gao, Jianping Li. (2022) DNA-Immobilized Special Conformation Recognition of L-Penicillamine Using a Chiral Molecular Imprinting Technique. Polymers, 14 (19): (4133). [PMID:36236082]
12. Xiaowei Huang, Wei Sun, Zhihua Li, Jiyong Shi, Ning Zhang, Yang Zhang, Xiaodong Zhai, Xuetao Hu, Xiaobo Zou. (2022) Hydrogen sulfide gas sensing toward on-site monitoring of chilled meat spoilage based on ratio-type fluorescent probe. FOOD CHEMISTRY, 396 (133654). [PMID:35853371]
13. Hao Yuan, Huangmei Zhou, Yu Zhao, Hao Tan, Rodolphe Antoine, Sanjun Zhang. (2022) Metal-Organic frameworks encapsulated Ag Nanoparticle-Nanoclusters with enhanced luminescence for simultaneous detection and removal of Chromium(VI). MICROCHEMICAL JOURNAL, 181 (107722). [PMID:]
14. Pu Li, Xiaoxiao Chen, Gaojun Wu, Zhe Wang, Chaobiao Huang. (2022) Ascorbic Acid Sensor Based on CdS QDs@PDA Fluorescence Resonance Energy Transfer. MOLECULES, 27 (7): (2097). [PMID:35408497]
15. Cong-Jie PAN, Tian-Tian CHEN, Long-Fei MA, Xue-Zhen QIN, Qiao-Qiao WEN, Su-Xiang FENG. (2022) One-pot facile synthesis of bright blue emitting silicon nanoparticles for sensitive detection of luteolin via inner filter effect. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 50 (100069). [PMID:]
16. Jun Zhang, Tingyang Xing, Min Zhang, Yunlong Zhou. (2022) Facile preparation of Cu2-xS supernanoparticles with an unambiguous SERS enhancement mechanism. CHEMICAL ENGINEERING JOURNAL, 434 (134457). [PMID:]
17. Zhang Wei, Zhang Yu, Liu Xin, Zhang Yue, Liu Yibing, Wang Wei, Su Rui, Sun Ying, Huang Yibing, Song Daqian, Wu Yanhua, Wang Xinghua. (2022) Ratiometric fluorescence and colorimetric dual-mode sensing platform based on carbon dots for detecting copper(II) ions and D-penicillamine. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (4): (1651-1662). [PMID:34988586]
18. Yaofa Liu, Haimei Li, Shulan Li, Xiaoyang Zhang, Jiaqiang Xiong, Fenglei Jiang, Yi Liu, Peng Jiang. (2021) Chiral Cu2–xSe Nanoparticles for Enhanced Synergistic Cancer Chemodynamic/Photothermal Therapy in the Second Near-Infrared Biowindow. ACS Applied Materials & Interfaces, 13 (51): (60933–60944). [PMID:34923825]
19. Jinglei Liu, Wenbo Yuan, Caifeng Li, Mengmeng Cheng, Yan Su, Lijian Xu, Tianfei Chu, Shifeng Hou. (2021) l-Cysteine-Modified Graphene Oxide-Based Membrane for Chiral Selective Separation. ACS Applied Materials & Interfaces, 13 (41): (49215–49223). [PMID:34628847]

References

1. Jing Fu, Yujin Miao, Di Zhang, Yongjie Zhang, Luyao Meng, Xinrui Ni, Jinglin Shen, Wei Qi. (2023) Polymer-Enabled Assembly of Au Nanoclusters with Luminescence Enhancement and Macroscopic Chirality. LANGMUIR, 39 (37): (13316–13324). [PMID:37682809]
2. Sen Hu, Yuning Jiang, Jiaying Cao, Qiangting Zheng, Yiping Wu, Xiaoyu Guo, Ye Ying, Xinling Liu, Ying Wen, Haifeng Yang. (2023) Gold nanoparticles decorated MoS2 nanosheets for sensing and degradation of carbamazepine in environmental wastewater. Environmental Technology & Innovation, 32 (103302). [PMID:]
3. Yarong Gu, Yuchao Du, Wenhe Wang, Xiaosheng Fang, Ziqing Li, Lijuan Zhao. (2023) Enantioselective inorganic nanomaterials with near-infrared circular-polarized-activated photothermal response. CHEMICAL ENGINEERING JOURNAL, 472 (144873). [PMID:]
4. Cheng Zhang, Mengna Liang, Congying Shao, Ziwei Li, Xue Cao, Yongxiang Wang, Yanan Wu, Shun Lu. (2023) Visual Detection and Sensing of Mercury Ions and Glutathione Using Fluorescent Copper Nanoclusters. ACS Applied Bio Materials, 6 (3): (1283–1293). [PMID:36788220]
5. Xun Zhou, Juerui Zhang, Dongyan Huang, Yinhui Yi, Kechen Wu, Gangbing Zhu. (2023) Nitrogen-doped Ti3C2 MXene quantum dots as an effective FRET ratio fluorometric probe for sensitive detection of Cu2+ and D-PA. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 293 (122484). [PMID:36796242]
6. Wang Siqi, Jin Yao, Ai Wenhui, Wang Xiufeng, Zhang Zhiqing, Zhou Ting, Zhang Guodong, Wang Fang. (2023) H2O2 actuated molybdenum oxide nanodots: Multi-enzyme-like activities, leverage of Fenton reaction, and dual-mode sensitive detection of alendronate sodium. Nano Research, 16 (10): (12106-12115). [PMID:]
7. Mengna Liang, Congying Shao, Qian Zhang, Cheng Zhang, Yongxiang Wang, Xingqun Zheng, Shun Lu. (2023) High-Performance Formaldehyde Sensing Using Paper-Based Fluorescent Copper Nanoclusters. IEEE SENSORS JOURNAL, 23 (3): (2076-2084). [PMID:]
8. Weihua Yu, Jianhua Kuang, Qingqing Hu, Zhonghua Wang, Yunwen Liao, Zhengjun Cheng. (2022) Ratiometric Detection of Al Based on the Mixing of D-penicillamine-Functionalized Copper Nanoclusters with Pyridoxal 5’-phosphate. ChemistrySelect, 7 (45): (e202203721). [PMID:]
9. Hongyu Chen, Fengshou Tian, Chao Lu. (2022) Engineering Plasmon-Enhanced Fluorescent Gold Nanoclusters Using Bovine Serum Albumin as a Novel Separation Layer for Improved Selectivity. ANALYTICAL CHEMISTRY, 94 (47): (16461–16469). [PMID:36383051]
10. Xun Sun, Xinyu Zhang, Hui Yan, Hongfei Wu, Shijian Cao, Wenchen Zhao, Ting Dong, An Zhou. (2023) Protective effect of curcumin on hepatolenticular degeneration through copper excretion and inhibition of ferroptosis. PHYTOMEDICINE, 113 (154539). [PMID:36898256]
11. Lianming Zhang, Kui Luo, Jingxia Gao, Jianping Li. (2022) DNA-Immobilized Special Conformation Recognition of L-Penicillamine Using a Chiral Molecular Imprinting Technique. Polymers, 14 (19): (4133). [PMID:36236082]
12. Xiaowei Huang, Wei Sun, Zhihua Li, Jiyong Shi, Ning Zhang, Yang Zhang, Xiaodong Zhai, Xuetao Hu, Xiaobo Zou. (2022) Hydrogen sulfide gas sensing toward on-site monitoring of chilled meat spoilage based on ratio-type fluorescent probe. FOOD CHEMISTRY, 396 (133654). [PMID:35853371]
13. Hao Yuan, Huangmei Zhou, Yu Zhao, Hao Tan, Rodolphe Antoine, Sanjun Zhang. (2022) Metal-Organic frameworks encapsulated Ag Nanoparticle-Nanoclusters with enhanced luminescence for simultaneous detection and removal of Chromium(VI). MICROCHEMICAL JOURNAL, 181 (107722). [PMID:]
14. Pu Li, Xiaoxiao Chen, Gaojun Wu, Zhe Wang, Chaobiao Huang. (2022) Ascorbic Acid Sensor Based on CdS QDs@PDA Fluorescence Resonance Energy Transfer. MOLECULES, 27 (7): (2097). [PMID:35408497]
15. Cong-Jie PAN, Tian-Tian CHEN, Long-Fei MA, Xue-Zhen QIN, Qiao-Qiao WEN, Su-Xiang FENG. (2022) One-pot facile synthesis of bright blue emitting silicon nanoparticles for sensitive detection of luteolin via inner filter effect. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 50 (100069). [PMID:]
16. Jun Zhang, Tingyang Xing, Min Zhang, Yunlong Zhou. (2022) Facile preparation of Cu2-xS supernanoparticles with an unambiguous SERS enhancement mechanism. CHEMICAL ENGINEERING JOURNAL, 434 (134457). [PMID:]
17. Zhang Wei, Zhang Yu, Liu Xin, Zhang Yue, Liu Yibing, Wang Wei, Su Rui, Sun Ying, Huang Yibing, Song Daqian, Wu Yanhua, Wang Xinghua. (2022) Ratiometric fluorescence and colorimetric dual-mode sensing platform based on carbon dots for detecting copper(II) ions and D-penicillamine. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (4): (1651-1662). [PMID:34988586]
18. Yaofa Liu, Haimei Li, Shulan Li, Xiaoyang Zhang, Jiaqiang Xiong, Fenglei Jiang, Yi Liu, Peng Jiang. (2021) Chiral Cu2–xSe Nanoparticles for Enhanced Synergistic Cancer Chemodynamic/Photothermal Therapy in the Second Near-Infrared Biowindow. ACS Applied Materials & Interfaces, 13 (51): (60933–60944). [PMID:34923825]
19. Jinglei Liu, Wenbo Yuan, Caifeng Li, Mengmeng Cheng, Yan Su, Lijian Xu, Tianfei Chu, Shifeng Hou. (2021) l-Cysteine-Modified Graphene Oxide-Based Membrane for Chiral Selective Separation. ACS Applied Materials & Interfaces, 13 (41): (49215–49223). [PMID:34628847]

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D-Penicillamine - 10mM in Water, high purity , CAS No.52-67-5