D-Phenylalanine - 98%, high purity , CAS No.673-06-3, Agonist of HCA 3 receptor

Item Number
P109094
Grouped product items
SKUSizeAvailabilityPrice Qty
P109094-5g
5g
In stock
$17.90
P109094-25g
25g
In stock
$47.90
P109094-100g
100g
In stock
$171.90
P109094-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$769.90
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HCA3 receptor Agonist

Basic Description

SynonymsD-.beta.-Phenyl-.alpha.-alanine | EN300-60166 | NSC 25005 | Phenylalanine,d- | Spectrum2_001558 | 4C53B247-2FE4-4464-92C0-9F3782A08966 | BDBM36161 | Dichloromethylmethane | DB02556 | KBio2_007341 | C02265 | IDI1_000453 | KBio1_000453 | D-PHENYLALANINE [WH
Specifications & PurityMoligand™, ≥98%
Shipped InNormal
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of HCA 3 receptor
Product Description

It is an essential amino acid with anti-depressant and analgesic activities. pharmaceutical intermediates, mainly used to treat, prevent osteoporosis, cardiovascular, diabetes, arterioscleros.

Associated Targets(Human)

HCAR3 Tchem Hydroxycarboxylic acid receptor 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA3 Tclin Carbonic anhydrase III (753 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA6 Tclin Carbonic anhydrase VI (993 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA5B Tclin Carbonic anhydrase VB (957 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA5A Tclin Carbonic anhydrase VA (1168 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA14 Tclin Carbonic anhydrase XIV (1305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC16A10 SLC16A10 protein (28 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ca13 Carbonic anhydrase XIII (322 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA4 Carbonic anhydrase IV (1713 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Carbonic anhydrase (69 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ca15 Carbonic anhydrase 15 (173 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAN2 Carbonic anhydrase 2 (140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Carbonic anhydrase-like protein, putative (25 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488184663
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488184663
IUPAC Name (2R)-2-amino-3-phenylpropanoic acid
INCHI InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1
InChi Key COLNVLDHVKWLRT-MRVPVSSYSA-N
Canonical SMILES C1=CC=C(C=C1)CC(C(=O)O)N
Isomeric SMILES C1=CC=C(C=C1)C[C@H](C(=O)O)N
WGK Germany 3
RTECS AY7533000
PubChem CID 71567
Molecular Weight 165.19
Beilstein 2804068
Reaxy-Rn 2804068

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot NumberCertificate TypeDateItem
B2320461Certificate of AnalysisJan 09, 2023 P109094
B2320468Certificate of AnalysisJan 09, 2023 P109094
B2320474Certificate of AnalysisJan 09, 2023 P109094
B2320551Certificate of AnalysisJan 09, 2023 P109094
B2320552Certificate of AnalysisJan 09, 2023 P109094
B2320553Certificate of AnalysisJan 09, 2023 P109094
B2320554Certificate of AnalysisJan 09, 2023 P109094
G2227445Certificate of AnalysisJun 09, 2022 P109094
G2227444Certificate of AnalysisJun 09, 2022 P109094
G2227443Certificate of AnalysisJun 09, 2022 P109094
G2227442Certificate of AnalysisJun 09, 2022 P109094
G2227441Certificate of AnalysisJun 09, 2022 P109094
C1810011Certificate of AnalysisJan 25, 2022 P109094
B2225730Certificate of AnalysisDec 08, 2021 P109094
B2225670Certificate of AnalysisDec 08, 2021 P109094
B2225666Certificate of AnalysisDec 08, 2021 P109094
B2225665Certificate of AnalysisDec 08, 2021 P109094
B2225664Certificate of AnalysisDec 08, 2021 P109094

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Chemical and Physical Properties

SolubilitySoluble in water (30 mg/ml), methanol (slightly), 1 M HCl (50 mg/ml), ethanol (<1 mg/ml at 25 °C), and DMSO (<1 mg/ml at 25 °C).
Specific Rotation[α]34 ° (C=2, H2O)
Melt Point(°C)273-276°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS AY7533000
Reaxy-Rn 2804068
Merck Index 7271

Related Documents

Citations of This Product

1. Jingzhi Yang, Yami Ran, Shaopeng Liu, Chenhao Ren, Yuntian Lou, Pengfei Ju, Guoliang Li, Xiaogang Li, Dawei Zhang.  (2023)  Synergistic D-Amino Acids Based Antimicrobial Cocktails Formulated via High-Throughput Screening and Machine Learning.  Advanced Science,  11  (9): (2307173).  [PMID:38126652] [10.1002/advs.202307173]
2. Zhiyang Xu, Yinzhou Yan, Xingyuan Wang, Xiaolei Wang, Zhixiang Zhou, Xi Yang, Tianrui Zhai.  (2023)  Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point.  Advanced Science,    (2308362).  [PMID:38072636] [10.1002/advs.202308362]
3. Jianrong Wang, Sha Han, Hongfang Zhao, Hongxia Li, Xiaohui Niu, Yi Wang, Kunjie Wang.  (2023)  Electrochemical enantioselective recognition by defined chiral linkers in polysaccharides modified with carbon quantum dots.  ELECTROANALYSIS,    (6): (e202300301).  [PMID:9169421] [10.1002/elan.202300301]
4. Li Yuchen, Xu Guangfu, Chen Jiaquan, Yu Tao, Miao Pandeng, Du Yingxiang.  (2023)  One-step synthesis of chiral molecularly imprinted polymer TiO2 nanoparticles for enantioseparation of phenylalanine in coated capillary electrochromatography.  MICROCHIMICA ACTA,  190  (7): (1-11).  [PMID:37391671] [10.1007/s00604-023-05854-4]
5. Niu Xiaohui, Zhao Rui, Yan Simeng, Li Hongxia, Yang Jing, Cao Kunjie, Liu Xiaoyu, Wang Kunjie.  (2023)  Chiral MOFs encapsulated by polymers with poly-metallic coordination as chiral biosensors.  MICROCHIMICA ACTA,  190  (6): (1-12).  [PMID:37208529] [10.1007/s00604-023-05807-x]
6. Hou Huipeng, Tang Shanshan, Wang Wei, Liu Miao, Liang Axin, Xie Bingteng, Yi Yue, Luo Aiqin.  (2023)  Electrochemical Chiral Recognizing Tryptophan Enantiomers Based on Chiral Metal-Organic Framework D-MOF.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  39  (6): (976-984).  [PMID:] [10.1007/s40242-023-3004-6]
7. Qian Ye, Jin Li, Yinyin Huang, Hanbin Wu, Yilin Li, Bin Yan.  (2023)  Preparation of a cyclodextrin metal-organic framework (CD-MOF) membrane for chiral separation.  Journal of Environmental Chemical Engineering,  11  (109250).  [PMID:] [10.1016/j.jece.2022.109250]
8. Jinglei Liu, Tianfei Chu, Mengmeng Cheng, Yan Su, Guizheng Zou, Shifeng Hou.  (2023)  Bovine serum albumin functional graphene oxide membrane for effective chiral separation.  JOURNAL OF MEMBRANE SCIENCE,  668  (121198).  [PMID:] [10.1016/j.memsci.2022.121198]
9. Yiyi Liu, Fangling Wu, Jiabin Wang, Ling Pu, Chuan-Fan Ding.  (2022)  Simultaneous chirality separation of amino acids and their derivative by natamycin based on mobility measurements.  ANALYTICA CHIMICA ACTA,  1227  (340298).  [PMID:36089312] [10.1016/j.aca.2022.340298]
10. Hai-Bin Qin, Jun-Ping Zhou, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng.  (2022)  Combing with redox regulation via quorum-sensing system and fermentation strategies for improving D-pantothenic acid production.  PROCESS BIOCHEMISTRY,  121  (681).  [PMID:] [10.1016/j.procbio.2022.08.012]
11. Wancheng Qin, Peng Zhou, Xinyu Xu, Chuanwei Huang, Gopalan Srinivasan, Yajun Qi, Tianjin Zhang.  (2022)  High-Performance Piezoelectric Nanogenerator Based on Low-Entropy Structured Nanofibers for a Multi-Mode Energy Harvesting and Self-Powered Ultraviolet Photodetector.  ACS Applied Electronic Materials,  (6): (2970–2978).  [PMID:] [10.1021/acsaelm.2c00411]
12. Yi Wu, Keren Lu, Fubin Pei, Yanghao Yan, Shasha Feng, Qingli Hao, Mingzhu Xia, Wu Lei.  (2022)  Construction of g-C3N4/Au/NH2-UiO-66 Z-scheme heterojunction for label-free photoelectrochemical recognition of D-penicillamine.  TALANTA,  248  (123617).  [PMID:35687949] [10.1016/j.talanta.2022.123617]
13. Hongxia Li, Letong Wang, Simeng Yan, Jinliang Chen, Mengmeng Zhang, Rui Zhao, Xiaohui Niu, Kunjie Wang.  (2022)  Fusiform-like metal-organic framework for enantioselective discrimination of tryptophan enantiomers.  ELECTROCHIMICA ACTA,  419  (140409).  [PMID:] [10.1016/j.electacta.2022.140409]
14. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding.  (2022)  The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation.  TALANTA,  243  (123363).  [PMID:35272154] [10.1016/j.talanta.2022.123363]
15. Xiaohui Niu, Simeng Yan, Letong Wang, Jinliang Chen, Rui Zhao, Hongxia Li, Jian Liu, Kunjie Wang.  (2022)  Induction of chiral polymers from metal-organic framework for stereoselective recognition.  ANALYTICA CHIMICA ACTA,  1196  (339546).  [PMID:35151404] [10.1016/j.aca.2022.339546]
16. Xiaohui Niu, Simeng Yan, Jinliang Chen, Hongxia Li, Kunjie Wang.  (2022)  Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework.  ELECTROCHIMICA ACTA,  405  (139809).  [PMID:] [10.1016/j.electacta.2021.139809]
17. Xin-hui Zhou, Qing Liu, Hai-shui Wang.  (2022)  Chiral resolution of DL-glutamic acid by a chiral additive.  JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,  97  (5): (1240-1246).  [PMID:] [10.1002/jctb.7018]
18. Xiaodan Wang, Fangping Yang, Huawei Yang, Xu Zhang, Haoyu Tang, Shifang Luan.  (2022)  Preparation of antibacterial polypeptides with different topologies and their antibacterial properties.  Biomaterials Science,  10  (3): (834-845).  [PMID:35005755] [10.1039/D1BM01620B]
19. Liu Nijuan, Liu Jingjing, Niu Xiaohui, Wang Jia, Guo Ruibin, Mo Zunli.  (2021)  An electrochemical chiral sensor based on the synergy of chiral ionic liquid and 3D-NGMWCNT for tryptophan enantioselective recognition.  MICROCHIMICA ACTA,  188  (5): (1-13).  [PMID:33839948] [10.1007/s00604-021-04818-w]
20. Jia Wang, Zunli Mo, Nijuan Liu, Ruibin Guo, Chao Shuai, Fang Chen, Yongxin Du, Jingjing Liu, Guigui Liu, Qibing Dong, Qinqin Gao, Ying Chen, Wentong Liu.  (2021)  Construction of electrochemical chiral interface of C3N4/Ppy/ self-assembled polysaccharide.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,  886  (115118).  [PMID:] [10.1016/j.jelechem.2021.115118]
21. Zou Jiao, Lan Xi-Wen, Zhao Guo-Qing, Huang Zhao-Ning, Liu Yi-Ping, Yu Jin-Gang.  (2020)  Immobilization of 6-O-α-maltosyl-β-cyclodextrin on the surface of black phosphorus nanosheets for selective chiral recognition of tyrosine enantiomers.  MICROCHIMICA ACTA,  187  (11): (1-11).  [PMID:33141322] [10.1007/s00604-020-04606-y]
22. Jiao Zou, Jin-Gang Yu.  (2020)  Nafion-stabilized black phosphorus nanosheets-maltosyl-β-cyclodextrin as a chiral sensor for tryptophan enantiomers.  Materials Science & Engineering C-Materials for Biological Applications,  112  (110910).  [PMID:32409064] [10.1016/j.msec.2020.110910]
23. Tingting Wang, Yuhuan Cheng, Yulian Zhang, Jinyin Zha, Jiannong Ye, Qingcui Chu, Guifang Cheng.  (2020)  β-cyclodextrin modified quantum dots as pseudo-stationary phase for direct enantioseparation based on capillary electrophoresis with laser-induced fluorescence detection.  TALANTA,  210  (120629).  [PMID:31987180] [10.1016/j.talanta.2019.120629]
24. Jiao Zou, Jin-Gang Yu.  (2019)  Chiral recognition of tyrosine enantiomers on a novel bis-aminosaccharides composite modified glassy carbon electrode.  ANALYTICA CHIMICA ACTA,  1088  (35).  [PMID:31623714] [10.1016/j.aca.2019.08.018]
25. Chunlei Ma, Wensheng Ren, Jianke Tang, Xiaoli Wang, Dongxin Ji, Rongqian Meng, Cuihong Zhang, Qi Wang.  (2019)  Copper nanocluster-based fluorescence enhanced determination of d-penicillamine.  LUMINESCENCE,  34  (7): (767-773).  [PMID:31267664] [10.1002/bio.3672]
26. Yanhua Tu, Beixuan He, Songyan Gao, Dandan Guo, Xinlei Jia, Xin Dong, Meili Guo.  (2019)  CtACO1 Overexpression Resulted in the Alteration of the Flavonoids Profile of Safflower.  MOLECULES,  24  (6): (1128).  [PMID:30901924] [10.3390/molecules24061128]
27. Huang Lu, Li Yanxia, Lin Qi, Lou Benyong, Chen Yiting.  (2018)  Enantioselective permeations of amino acids through l-proline-modified gold nanochannel membrane: an experimental and theoretical study.  AMINO ACIDS,  50  (11): (1549-1556).  [PMID:30073606] [10.1007/s00726-018-2629-0]
28. Lili Guo, Baozhu Yang, Datong Wu, Yongxin Tao, Yong Kong.  (2018)  Chiral Sensing Platform Based on the Self-Assemblies of Diphenylalanine and Oxalic Acid.  ANALYTICAL CHEMISTRY,  90  (8): (5451–5458).  [PMID:29595059] [10.1021/acs.analchem.8b00762]
29. Yanni Miao, Qi Liu, Wei Wang, Li Liu, Li Wang.  (2017)  Enantioseparation of amino acids by micellar capillary electrophoresis using binary chiral selectors and determination of D-glutamic acid and D-aspartic acid in rice wine.  JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES,      [PMID:] [10.1080/10826076.2017.1364263]
30. Xiaomei Lu, Jie Tang, Xinxin Dang, Xiaoli Jing, Kailin Xu, Hui Li, Bing Liang.  (2017)  Chiral recognition and determination of enantiomeric excess of chiral compounds by UV-visible-shortwave near infrared diffuse reflectance spectroscopy with chemometrics.  RSC Advances,  (22): (13552-13560).  [PMID:] [10.1039/C6RA24952C]
31. Yongxin Tao, Xiaogang Gu, Baozhu Yang, Linhong Deng, Liping Bao, Yong Kong, Fuqiang Chu, Yong Qin.  (2017)  Electrochemical Enantioselective Recognition in a Highly Ordered Self-Assembly Framework.  ANALYTICAL CHEMISTRY,  89  (3): (1900–1906).  [PMID:28208293] [10.1021/acs.analchem.6b04377]
32. Datong Wu, Ying Zhou, Pengfei Cai, Shanshan Shen, Yuanjiang Pan.  (2015)  Specific cooperative effect for the enantiomeric separation of amino acids using aqueous two-phase systems with task-specific ionic liquids.  JOURNAL OF CHROMATOGRAPHY A,  1395  (65).  [PMID:25888099] [10.1016/j.chroma.2015.03.047]
33. Xiao-Yan Liu, Hong-Xun Fang, Li-Ping Yu.  (2013)  Molecularly imprinted photonic polymer based on β-cyclodextrin for amino acid sensing.  TALANTA,  116  (283).  [PMID:24148405] [10.1016/j.talanta.2013.05.003]
34. Chen Qi,Wenke Yang,Fuyan He,Jinshui Yao.  (2020-09-13)  The Thermal Properties and Degradability of Chiral Polyester-Imides Based on Several l/d-Amino Acids..  Polymers,  12  ((9)):   [PMID:32916788]

References

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4. Isao Nishimori,Saburo Onishi,Daniela Vullo,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran.  (2007-05-15)  Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines..  Bioorganic & medicinal chemistry,  15  ((15)): (5351-5357).  [PMID:17499996]
5. Daniela Vullo,Alessio Innocenti,Isao Nishimori,Andrea Scozzafava,Kai Kaila,Claudiu T Supuran.  (2007-06-02)  Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines..  Bioorganic & medicinal chemistry letters,  17  ((15)): (4107-4112).  [PMID:17540561]
6. Silvia Pastorekova,Daniela Vullo,Isao Nishimori,Andrea Scozzafava,Jaromir Pastorek,Claudiu T Supuran.  (2008-02-26)  Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines..  Bioorganic & medicinal chemistry,  16  ((7)): (3530-3536).  [PMID:18294854]
7. Suneela S Dhaneshwar,Mukta Chail,Mahavir Patil,Salma Naqvi,Gaurav Vadnerkar.  (2008-05-13)  Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats..  European journal of medicinal chemistry,  44  ((1)): (131-142).  [PMID:18472188]
8. Daniela Vullo,Isao Nishimori,Andrea Scozzafava,Claudiu T Supuran.  (2008-07-17)  Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines..  Bioorganic & medicinal chemistry letters,  18  ((15)): (4303-4307).  [PMID:18627905]
9. Alessio Innocenti,Sabrina A Zimmerman,Andrea Scozzafava,James G Ferry,Claudiu T Supuran.  (2008-10-22)  Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines..  Bioorganic & medicinal chemistry letters,  18  ((23)): (6194-6198).  [PMID:18930395]
10. Semra Isik,Feray Kockar,Meltem Aydin,Oktay Arslan,Ozen Ozensoy Guler,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran.  (2009-02-24)  Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids..  Bioorganic & medicinal chemistry letters,  19  ((6)): (1662-1665).  [PMID:19231177]
11. Suneela S Dhaneshwar,Neha Gairola,Mini Kandpal,Gaurav Vadnerkar,Lokesh Bhatt,Badal Rathi,S S Kadam.  (2009-05-16)  Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease..  European journal of medicinal chemistry,  44  ((10)): (3922-3929).  [PMID:19442419]
12. Alessio Innocenti,Mika Hilvo,Seppo Parkkila,Andrea Scozzafava,Claudiu T Supuran.  (2009-05-26)  Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines..  Bioorganic & medicinal chemistry letters,  19  ((13)): (3430-3433).  [PMID:19464888]
13. Alessio Innocenti,Rebecca A Hall,Andrea Scozzafava,Fritz A Mühlschlegel,Claudiu T Supuran.  (2010-01-12)  Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids..  Bioorganic & medicinal chemistry,  18  ((3)): (1034-1037).  [PMID:20061162]
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Solution Calculators