Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
V101067-1g | 1g | In stock | $27.90 | |
V101067-5g | 5g | In stock | $123.90 | |
V101067-10g | 10g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $223.90 | |
V101067-25g | 25g | Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks. | $502.90 | |
V101067-100g | 100g | In stock | $1,807.90 | |
V101067-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $8,133.90 |
Synonyms | EINECS 211-368-9 | C06417 | DVA | (R)-alpha-Aminoisovaleric acid | NSC-20654 | AKOS006240045 | D-(-)-VALINE | H-D-Val-OH | NCGC00159470-02 | R-Valine | Thioethyl alcohol | AM82362 | (R)-2-Amino-3-methylbutyric acid | D-Val | A847288 | VALNEMULIN HYDROCHLO |
---|---|
Specifications & Purity | ≥98% |
Shipped In | Normal |
Product Description | D-Valine is a selective inhibitor of cell proliferation. It inhibit cells that lack the enzyme D-amino acid oxidase. D-Valine has been shown to inhibit fibroblast growth while allowing selective growth of epithelial cells. L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|
Pubchem Sid | 488184661 |
---|---|
Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488184661 |
IUPAC Name | (2R)-2-amino-3-methylbutanoic acid |
INCHI | InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1 |
InChi Key | KZSNJWFQEVHDMF-SCSAIBSYSA-N |
Canonical SMILES | CC(C)C(C(=O)O)N |
Isomeric SMILES | CC(C)[C@H](C(=O)O)N |
WGK Germany | 3 |
RTECS | YV9360000 |
PubChem CID | 71563 |
Molecular Weight | 117.15 |
Beilstein | 1721135 |
Reaxy-Rn | 1721135 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
E2308605 | Certificate of Analysis | Nov 09, 2022 | V101067 |
E2415060 | Certificate of Analysis | Nov 09, 2022 | V101067 |
L2214542 | Certificate of Analysis | Nov 09, 2022 | V101067 |
L2214543 | Certificate of Analysis | Nov 09, 2022 | V101067 |
L2214544 | Certificate of Analysis | Nov 09, 2022 | V101067 |
L2214545 | Certificate of Analysis | Nov 09, 2022 | V101067 |
L2214546 | Certificate of Analysis | Nov 09, 2022 | V101067 |
L2214547 | Certificate of Analysis | Nov 09, 2022 | V101067 |
J2219115 | Certificate of Analysis | Oct 21, 2022 | V101067 |
L1812106 | Certificate of Analysis | Sep 21, 2022 | V101067 |
D1813135 | Certificate of Analysis | Feb 18, 2022 | V101067 |
B2317052 | Certificate of Analysis | May 08, 2021 | V101067 |
B2317071 | Certificate of Analysis | May 08, 2021 | V101067 |
K2209070 | Certificate of Analysis | May 08, 2021 | V101067 |
K2209071 | Certificate of Analysis | May 08, 2021 | V101067 |
Solubility | Soluble in water (56 mg/ml at 20° C), Aqueous Acid, and 3N HCI. Insoluble in ethanol, and ether. |
---|---|
Specific Rotation[α] | -27 ° (C=8, 6mol/L HCl) |
Melt Point(°C) | 302-303°C |
WGK Germany | 3 |
---|---|
RTECS | YV9360000 |
Reaxy-Rn | 1721135 |
1. Zhiyang Xu, Yinzhou Yan, Xingyuan Wang, Xiaolei Wang, Zhixiang Zhou, Xi Yang, Tianrui Zhai. (2023) Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point. Advanced Science, (2308362). [PMID:38072636] [10.1002/advs.202308362] |
2. Li Gao, Piao Xu, Jiaoyan Ren. (2023) A sensitive and economical method for simultaneous determination of D/L- amino acids profile in foods by HPLC-UV: Application in fermented and unfermented foods discrimination. FOOD CHEMISTRY, 410 (135382). [PMID:36628920] [10.1016/j.foodchem.2022.135382] |
3. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding. (2022) The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation. TALANTA, 243 (123363). [PMID:35272154] [10.1016/j.talanta.2022.123363] |
4. Jun Zhang, Tingyang Xing, Min Zhang, Yunlong Zhou. (2022) Facile preparation of Cu2-xS supernanoparticles with an unambiguous SERS enhancement mechanism. CHEMICAL ENGINEERING JOURNAL, 434 (134457). [PMID:] [10.1016/j.cej.2021.134457] |
5. Deng Jun, Wu Sai, Yao Mengyun, Gao Changyou. (2016) Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles. Scientific Reports, 6 (1): (1-12). [PMID:27531648] [10.1038/srep31595] |
1. Gerald I Richard,Hadi M Marwani,Shan Jiang,Sayo O Fakayode,Mark Lowry,Robert M Strongin,Isiah M Warner. (2008-05-24) Chiral recognition of amino acids by use of a fluorescent resorcinarene.. Applied spectroscopy, 62 ((5)): (476-480). [PMID:18498687] |
2. Iris Thondorf,Valerie Voigt,Sarah Schäfer,Sabine Gebauer,Katja Zebisch,Linda Laug,Matthias Brandsch. (2011-10-01) Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).. Bioorganic & medicinal chemistry, 19 ((21)): (6409-6418). [PMID:21955456] |
3. Brian R Tuinema,Sarah A Reid-Yu,Brian K Coombes. (2014-11-27) Salmonella evades D-amino acid oxidase to promote infection in neutrophils.. mBio, 5 ((6)): (e01886-e01886). [PMID:25425233] |
4. Kimberly A Smith,Guillaume Voiriot,Haiyang Tang,Dustin R Fraidenburg,Shanshan Song,Hisao Yamamura,Aya Yamamura,Qiang Guo,Jun Wan,Nicole M Pohl,Mohammad Tauseef,Rolf Bodmer,Karen Ocorr,Patricia A Thistlethwaite,Gabriel G Haddad,Frank L Powell,Ayako Makino,Dolly Mehta,Jason X-J Yuan. (2015-01-09) Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.. American journal of respiratory cell and molecular biology, 53 ((3)): (355-367). [PMID:25569851] |
5. Dean P J Kavanagh,Shankar Suresh,Philip N Newsome,Jon Frampton,Neena Kalia. (2015-07-01) Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut.. Stem cells (Dayton, Ohio), 33 ((9)): (2785-2797). [PMID:26124062] |
6. Shanshan Song,Aya Yamamura,Hisao Yamamura,Ramon J Ayon,Kimberly A Smith,Haiyang Tang,Ayako Makino,Jason X-J Yuan. (2014-06-13) Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.. American journal of physiology. Cell physiology, 307 ((4)): (C373-C383). [PMID:24920677] |
7. Stefan M Gysler,Melissa J Mulla,Meredith Stuhlman,Anna K Sfakianaki,Michael J Paidas,Nancy L Stanwood,Aileen Gariepy,Jan J Brosens,Lawrence W Chamley,Vikki M Abrahams. (2014-07-30) Vitamin D reverses aPL-induced inflammation and LMWH-induced sFlt-1 release by human trophoblast.. American journal of reproductive immunology (New York, N.Y. : 1989), 73 ((3)): (242-250). [PMID:25070806] |
8. Zhiyang Xu, Yinzhou Yan, Xingyuan Wang, Xiaolei Wang, Zhixiang Zhou, Xi Yang, Tianrui Zhai. (2023) Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point. Advanced Science, (2308362). [PMID:38072636] [10.1002/advs.202308362] |
9. Li Gao, Piao Xu, Jiaoyan Ren. (2023) A sensitive and economical method for simultaneous determination of D/L- amino acids profile in foods by HPLC-UV: Application in fermented and unfermented foods discrimination. FOOD CHEMISTRY, 410 (135382). [PMID:36628920] [10.1016/j.foodchem.2022.135382] |
10. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding. (2022) The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation. TALANTA, 243 (123363). [PMID:35272154] [10.1016/j.talanta.2022.123363] |
11. Jun Zhang, Tingyang Xing, Min Zhang, Yunlong Zhou. (2022) Facile preparation of Cu2-xS supernanoparticles with an unambiguous SERS enhancement mechanism. CHEMICAL ENGINEERING JOURNAL, 434 (134457). [PMID:] [10.1016/j.cej.2021.134457] |
12. Deng Jun, Wu Sai, Yao Mengyun, Gao Changyou. (2016) Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles. Scientific Reports, 6 (1): (1-12). [PMID:27531648] [10.1038/srep31595] |