D4476 - 10mM in DMSO, high purity , CAS No.301836-43-1

Item Number

D423116

• Synonyms: 301836-43-1 | D4476 | CK1 Inhibitor | D 4476 | casein kinase I inhibitor | D-4476 | Casein Kinase I Inhibitor, D4476 | 4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide | 4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-2-yl-1H-imida
• Specifications & Purity: Moligand™, 10mM in DMSO
• Biochemical and Physiological Mechanisms: D4476 is a cell-permeable triaryl substituted imidazolo compound that acts as a selective inhibitor of casein kinase 1 (CK1) and TGFβ RI (TGF-βtype-I receptor, ALK5). Weak inhibitor of Polycystin-1 (PKD1), p38? (p38α MAPK) and only weakly affects the acti
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™

Product Description

D4476, a cell-permeant inhibitor of CK1δ (IC90 <10 uM), originally identified as inhibitors of activin receptor-like kinase ALK5.
A cell-permeable triaryl substituted imidazolo compound that acts as a selective inhibitor of casein kinase 1 (CK1).