Dansyl-NECA - ≥99%(HPLC), high purity , CAS No.219982-12-4

  • ≥99%(HPLC)
Item Number
D288196
Grouped product items
SKUSizeAvailabilityPrice Qty
D288196-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$167.90

Potent and selective fluorescent adenosine A1agonist

Basic Description

Specifications & Purity≥99%(HPLC)
Biochemical and Physiological MechanismsHigh affinity and selective fluorescent adenosine A1receptor agonist (Kivalues are 27, 3600 and 4300 nM for A1, A3and A2receptors, respectively). Permits visualization of A1receptors in the rat cerebellar cortex.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S,3S,4R,5R)-5-[6-[6-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]hexylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
INCHI InChI=1S/C30H40N8O6S/c1-4-31-29(41)26-24(39)25(40)30(44-26)38-18-35-23-27(33-17-34-28(23)38)32-15-7-5-6-8-16-36-45(42,43)22-14-10-11-19-20(22)12-9-13-21(19)37(2)3/h9-14,17-18,24-26,30,36,39-40H,4-8,15-16H2,1-3H3,(H,31,41)(H,32,33,34)/t24-,25+,26-,30+/m0/s1
InChi Key CJDPJPUVKHWZHU-YRIIQKNPSA-N
Canonical SMILES CCNC(=O)C1C(C(C(O1)N2C=NC3=C(N=CN=C32)NCCCCCCNS(=O)(=O)C4=CC=CC5=C4C=CC=C5N(C)C)O)O
Isomeric SMILES CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)NCCCCCCNS(=O)(=O)C4=CC=CC5=C4C=CC=C5N(C)C)O)O
PubChem CID 10009321
Molecular Weight 640.75

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 64.08, Max Conc. mM: 100

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