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Dansyl-NECA - ≥99%(HPLC), high purity , CAS No.219982-12-4
Potent and selective fluorescent adenosine A1agonist
Basic Description Specifications & Purity ≥99%(HPLC) Biochemical and Physiological Mechanisms High affinity and selective fluorescent adenosine A1receptor agonist (Kivalues are 27, 3600 and 4300 nM for A1, A3and A2receptors, respectively). Permits visualization of A1receptors in the rat cerebellar cortex. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (2S,3S,4R,5R)-5-[6-[6-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]hexylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide INCHI InChI=1S/C30H40N8O6S/c1-4-31-29(41)26-24(39)25(40)30(44-26)38-18-35-23-27(33-17-34-28(23)38)32-15-7-5-6-8-16-36-45(42,43)22-14-10-11-19-20(22)12-9-13-21(19)37(2)3/h9-14,17-18,24-26,30,36,39-40H,4-8,15-16H2,1-3H3,(H,31,41)(H,32,33,34)/t24-,25+,26-,30+/m0/s1 InChi Key CJDPJPUVKHWZHU-YRIIQKNPSA-N Canonical SMILES CCNC(=O)C1C(C(C(O1)N2C=NC3=C(N=CN=C32)NCCCCCCNS(=O)(=O)C4=CC=CC5=C4C=CC=C5N(C)C)O)O Isomeric SMILES CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)NCCCCCCNS(=O)(=O)C4=CC=CC5=C4C=CC=C5N(C)C)O)O PubChem CID 10009321 Molecular Weight 640.75
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 64.08, Max Conc. mM: 100
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