| 1. Kass IJ, Sampson NS.. (1998) The importance of GLU361 position in the reaction catalyzed by cholesterol oxidase., 8 (19): [PMID:9873599] [10.1016/s0960-894x(98)00478-8] |
| 2. Farr CD, Tabet MR, Ball WJ, Fishwild DM, Wang X, Nair AC, Welsh WJ.. (2002) Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis., 45 (15): [PMID:12109909] [10.1021/jm0102811] |
| 3. Poplawski J, Lozowicka B, Dubis AT, Lachowska B, Witkowski S, Siluk D, Petrusewicz J, Kaliszan R, Cybulski J, Strzałkowska M, Chilmonczyk Z.. (2000) Synthesis and hypolipidemic and antiplatelet activities of alpha-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo)., 43 (20): [PMID:11020281] [10.1021/jm000905n] |
| 4. McNeal ET, Lewandowski GA, Daly JW, Creveling CR.. (1985) [3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs., 28 (3): [PMID:2579237] [10.1021/jm00381a019] |
| 5. Foster AB, Jarman M, Leung CS, Rowlands MG, Taylor GN.. (1983) Analogues of aminoglutethimide: selective inhibition of cholesterol side-chain cleavage., 26 (1): [PMID:6827528] [10.1021/jm00355a011] |
| 6. Spencer TA, Li D, Russel JS, Collins JL, Bledsoe RK, Consler TG, Moore LB, Galardi CM, McKee DD, Moore JT, Watson MA, Parks DJ, Lambert MH, Willson TM.. (2001) Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha., 44 (6): [PMID:11300870] [10.1021/jm0004749] |
| 7. Oshige M, Kuramochi K, Ohta K, Ogawa A, Kuriyama H, Sugawara F, Kobayashi S, Sakaguchi K.. (2004) Molecular design of cholesterols as inhibitors of DNA polymerase alpha., 47 (20): [PMID:15369402] [10.1021/jm030553v] |
| 8. Lill MA, Winiger F, Vedani A, Ernst B.. (2005) Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals., 48 (18): [PMID:16134935] [10.1021/jm050403f] |
| 9. Ekins S, Mankowski DC, Hoover DJ, Lawton MP, Treadway JL, Harwood HJ.. (2007) Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors., 35 (3): [PMID:17194716] [10.1124/dmd.106.013888] |
| 10. Nes WD, Patterson GW. (1981) Effects of Tetracyclic and Pentacyclic Triterpenoids on Growth of Phytophthora cactorum, 44 (2): [10.1021/np50014a012] |
| 11. Kubo I, Muroi H, Kubo A.. (1994) Naturally occurring antiacne agents., 57 (1): [PMID:8158169] [10.1021/np50103a002] |
| 12. Khan SA.. (2008) Synthesis, characterization and in vitro antibacterial activity of new steroidal 5-en-3-oxazolo and thiazoloquinoxaline., 43 (9): [PMID:18455270] [10.1016/j.ejmech.2007.12.008] |
| 13. Khan SA, Saleem K, Khan Z.. (2008) Synthesis, structure elucidation and antibacterial evaluation of new steroidal -5-en-7-thiazoloquinoxaline derivatives., 43 (10): [PMID:18440096] [10.1016/j.ejmech.2007.09.022] |
| 14. Khan SA, Singh N, Saleem K.. (2008) Synthesis, characterization and in vitro antibacterial activity of thiourea and urea derivatives of steroids., 43 (10): [PMID:18294737] [10.1016/j.ejmech.2007.12.012] |
| 15. Carvalho JF, Cruz Silva MM, Moreira JN, Simões S, Sá E Melo ML.. (2009) Efficient chemoenzymatic synthesis, cytotoxic evaluation, and SAR of epoxysterols., 52 (13): [PMID:19473028] [10.1021/jm9003973] |
| 16. Wei X, Rodríguez AD, Wang Y, Franzblau SG.. (2008) Synthesis and in vitro biological evaluation of ring B abeo-sterols as novel inhibitors of Mycobacterium tuberculosis., 18 (20): [PMID:18818073] [10.1016/j.bmcl.2008.09.029] |
| 17. de Medina P, Paillasse MR, Payré B, Silvente-Poirot S, Poirot M.. (2009) Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases., 52 (23): [PMID:19821610] [10.1021/jm901063e] |
| 18. Mahidol C, Prawat H, Sangpetsiripan S, Ruchirawat S.. (2009) Bioactive scalaranes from the Thai sponge Hyrtios gumminae., 72 (10): [PMID:19788270] [10.1021/np900267v] |
| 19. Liu Y, Nair MG.. (2010) An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds., 73 (7): [PMID:20565070] [10.1021/np1000945] |
| 20. Bracha AL, Ramanathan A, Huang S, Ingber DE, Schreiber SL.. (2010) Carbon metabolism-mediated myogenic differentiation., 6 (3): [PMID:20081855] [10.1038/nchembio.301] |
| 21. Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW.. (2006) Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization., 2 (5): [PMID:16565714] [10.1038/nchembio782] |
| 22. PubChem BioAssay data set, |
| 23. (2008) Casarett and Doull's Toxicology The Basic Science of Poisons, 7th edition, |
| 24. Quang TH, Ha TT, Minh CV, Kiem PV, Huong HT, Ngan NT, Nhiem NX, Tung NH, Thao NP, Thuy DT, Song SB, Boo HJ, Kang HK, Kim YH.. (2011) Cytotoxic and PPARs transcriptional activities of sterols from the Vietnamese soft coral Lobophytum laevigatum., 21 (10): [PMID:21507644] [10.1016/j.bmcl.2011.03.089] |
| 25. Reina E, Puentes C, Rojas J, García J, Ramos FA, Castellanos L, Aragón M, Ospina LF.. (2011) Fuscoside E: a strong anti-inflammatory diterpene from Caribbean octocoral Eunicea fusca., 21 (19): [PMID:21865038] [10.1016/j.bmcl.2011.07.092] |
| 26. PubChem BioAssay data set, |
| 27. Pérez-Díaz JO, Rárová L, Muñoz Ocampo JP, Magaña-Vergara NE, Farfán N, Strnad M, Santillan R.. (2012) Synthesis and biological activity of 23-ethylidene-26-hydroxy-22-oxocholestane derivatives from spirostanic sapogenins., 51 [PMID:22417637] [10.1016/j.ejmech.2012.02.020] |
| 28. Johnston JB, Singh AA, Clary AA, Chen CK, Hayes PY, Chow S, De Voss JJ, Ortiz de Montellano PR.. (2012) Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1., 20 (13): [PMID:22647881] [10.1016/j.bmc.2012.05.003] |
| 29. Janvilisri T, Venter H, Shahi S, Reuter G, Balakrishnan L, van Veen HW.. (2003) Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis., 278 (1): [PMID:12668685] [10.1074/jbc.m301358200] |
| 30. Wang E, Casciano CN, Clement RP, Johnson WW.. (2000) Cholesterol interaction with the daunorubicin binding site of P-glycoprotein., 276 (1): [PMID:11027568] [10.1006/bbrc.2000.3554] |
| 31. USP Dictionary of USAN and International Names (2010 edition) and USAN registrations 2007-date, |
| 32. Karaki F, Ohgane K, Dodo K, Hashimoto Y.. (2013) Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect., 21 (17): [PMID:23830695] [10.1016/j.bmc.2013.06.022] |
| 33. Unpublished dataset, |
| 34. Unpublished dataset, |
| 35. De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.. (2013) Structure-based identification of OATP1B1/3 inhibitors., 83 (6): [PMID:23571415] [10.1124/mol.112.084152] |
| 36. Higgins CD, Koellhoffer JF, Chandran K, Lai JR.. (2013) C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: effects of conjugation to cholesterol and side chain-side chain crosslinking., 23 (19): [PMID:23962564] [10.1016/j.bmcl.2013.07.056] |
| 37. Ohgane K, Karaki F, Noguchi-Yachide T, Dodo K, Hashimoto Y.. (2014) Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein., 24 (15): [PMID:24928400] [10.1016/j.bmcl.2014.05.064] |
| 38. Kim HJ, Fei X, Cho SC, Choi BY, Ahn HC, Lee K, Seo SY, Keum YS.. (2015) Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1., 25 (23): [PMID:26508549] [10.1016/j.bmcl.2015.10.034] |
| 39. British National Formulary (72nd edition), |
| 40. Qiu R, Wang Y.. (2018) Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Agonists as Potential Small Molecule Therapeutics for Cancer Immunotherapy., 61 (14): [PMID:29412659] [10.1021/acs.jmedchem.7b01314] |
| 41. Walker MA.. (2017) Improvement in aqueous solubility achieved via small molecular changes., 27 (23): [PMID:29100802] [10.1016/j.bmcl.2017.09.041] |
| 42. Unpublished dataset, |
| 43. Deng G, Zhou B, Wang J, Chen Z, Gong L, Gong Y, Wu D, Li Y, Zhang H, Yang X.. (2019) Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives., 168 [PMID:30822712] [10.1016/j.ejmech.2019.02.025] |
| 44. (2017) Post-Translational Regulation of Catalytic Activities of Cytochrome P450 46A1 and Uses Thereof, |
| 45. Sun D,Peyear TA,Bennett WFD,Holcomb M,He S,Zhu F,Lightstone FC,Andersen OS,Ingólfsson HI. (2020) Assessing the Perturbing Effects of Drugs on Lipid Bilayers Using Gramicidin Channel-Based In Silico and In Vitro Assays., 63 (20.0): [PMID:32945672] [10.1021/acs.jmedchem.0c00958] |
| 46. Meijer FA,van den Oetelaar MCM,Doveston RG,Sampers ENR,Brunsveld L. (2021) Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site., 12 (4.0): [PMID:33854703] [10.1021/acsmedchemlett.1c00029] |
| 47. Niu C, Leavitt LS, Lin Z, Paguigan ND, Sun L, Zhang J, Torres JP, Raghuraman S, Chase K, Cadeddu R, Karthikeyan M, Bortolato M, Reilly CA, Hughen RW, Light AR, Olivera BM, Schmidt EW.. (2021) Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, Conus geographus., 64 (10.0): [PMID:33949869] [10.1021/acs.jmedchem.1c00562] |
