ID: ALA1161637

Max Phase: Preclinical

Molecular Formula: HIO4

Molecular Weight: 191.91

Molecule Type: Small molecule

Representations

Synonyms (1): Periodate
Synonyms from Alternative Forms(1):

Canonical SMILES:  [O-][I+3]([O-])([O-])O

Standard InChI:  InChI=1S/HIO4/c2-1(3,4)5/h(H,2,3,4,5)

Standard InChI Key:  KHIWWQKSHDUIBK-UHFFFAOYSA-N

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Properties

Molecular Weight: 191.91

Molecular Weight (Monoisotopic): 191.8920

AlogP: -7.12

#Rotatable Bonds: 0

Polar Surface Area: 89.41

Molecular Species:

HBA: 4

HBD: 1

#RO5 Violations: 0

HBA (Lipinski): 4

HBD (Lipinski): 1

#RO5 Violations (Lipinski): 0

CX Acidic pKa:

CX Basic pKa:

CX LogP:

CX LogD:

Aromatic Rings: 0

Heavy Atoms: 5

QED Weighted: 0.39

Np Likeness Score: -0.02

References

1. Innocenti A, Vullo D, Scozzafava A, Supuran CT..  (2005)  Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.,  15  (3): [PMID:15664814] [10.1016/j.bmcl.2004.11.056]

Source

Source(1):

• Scientific Literature