| 1. Glennon RA, Smith JD, Ismaiel AM, el-Ashmawy M, Battaglia G, Fischer JB.. (1991) Identification and exploitation of the sigma-opiate pharmacophore., 34 (3): [PMID:1848295] [10.1021/jm00107a033] |
| 2. Smith RA, White RL, Krantz A.. (1988) Stereoisomers of allenic amines as inactivators of monoamine oxidase type B. Stereochemical probes of the active site., 31 (8): [PMID:3397993] [10.1021/jm00403a012] |
| 3. Chu DT, Nordeen CW, Hardy DJ, Swanson RN, Giardina WJ, Pernet AG, Plattner JJ.. (1991) Synthesis, antibacterial activities, and pharmacological properties of enantiomers of temafloxacin hydrochloride., 34 (1): [PMID:1846917] [10.1021/jm00105a025] |
| 4. Caron G, Ermondi G.. (2005) Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk)., 48 (9): [PMID:15857133] [10.1021/jm048980b] |
| 5. Obach RS, Lombardo F, Waters NJ.. (2008) Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds., 36 (7): [PMID:18426954] [10.1124/dmd.108.020479] |
| 6. Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.. (2010) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species., 23 (1): [PMID:20014752] [10.1021/tx900326k] |
| 7. Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.. (2011) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)., 7 (12): [PMID:22194678] [10.1371/journal.pcbi.1002310] |
| 8. Lewin AH, Miller GM, Gilmour B.. (2011) Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class., 19 (23): [PMID:22037049] [10.1016/j.bmc.2011.10.007] |
| 9. Sakatis MZ, Reese MJ, Harrell AW, Taylor MA, Baines IA, Chen L, Bloomer JC, Yang EY, Ellens HM, Ambroso JL, Lovatt CA, Ayrton AD, Clarke SE.. (2012) Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds., 25 (10): [PMID:22931300] [10.1021/tx300075j] |
| 10. Wu X, Huang W, Prasad PD, Seth P, Rajan DP, Leibach FH, Chen J, Conway SJ, Ganapathy V.. (1999) Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter., 290 (1): [PMID:10454528] |
| 11. Wu X, Prasad PD, Leibach FH, Ganapathy V.. (1998) cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family., 246 (1): [PMID:9618255] [10.1006/bbrc.1998.8669] |
| 12. Wu X, Kekuda R, Huang W, Fei YJ, Leibach FH, Chen J, Conway SJ, Ganapathy V.. (1998) Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain., 273 (1): [PMID:9830022] [10.1074/jbc.273.49.32776] |
| 13. Noorizadeh H, Noorizadeh M, Farmany A. (2012) Advanced QSRR models of toxicological screening of basic drugs in whole blood by UPLC-TOFMS, 21 (12): [10.1007/s00044-012-9977-1] |
| 14. Ding D, Nickell JR, Deaciuc AG, Penthala NR, Dwoskin LP, Crooks PA.. (2013) Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake., 21 (21): [PMID:23993667] [10.1016/j.bmc.2013.08.001] |
| 15. Unpublished dataset, |
| 16. Settimo L, Bellman K, Knegtel RM.. (2013) Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds., [PMID:24249037] [10.1007/s11095-013-1232-z] |
| 17. Reese EA, Norimatsu Y, Grandy MS, Suchland KL, Bunzow JR, Grandy DK.. (2014) Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine., 57 (2): [PMID:24354319] [10.1021/jm401316v] |
| 18. Ding D, Nickell JR, Dwoskin LP, Crooks PA.. (2015) Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2., 25 (13): [PMID:25991431] [10.1016/j.bmcl.2015.04.105] |
| 19. WHO Anatomical Therapeutic Chemical Classification, |
| 20. Geldenhuys WJ, Yonutas HM, Morris DL, Sullivan PG, Darvesh AS, Leeper TC.. (2016) Identification of small molecules that bind to the mitochondrial protein mitoNEET., 26 (21): [PMID:27687671] [10.1016/j.bmcl.2016.09.009] |
| 21. Glennon RA.. (2017) The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse., 60 (7): [PMID:28244748] [10.1021/acs.jmedchem.7b00085] |
| 22. Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.. (2016) DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans., 21 (4): [PMID:26948801] [10.1016/j.drudis.2016.02.015] |
| 23. Unpublished dataset, |
| 24. Ellen Van Damme. (2021) Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activity, [10.6019/CHEMBL4651402] |
