ID: ALA1231052
Chembl Id: CHEMBL1231052
Cas Number: 7440-38-2
PubChem CID: 5359596
Product Number: A433450
Max Phase: Approved
Molecular Formula: H3As
Molecular Weight: 77.95
Molecule Type: Small molecule
Associated Items:
Synonyms: Show More⌵
Canonical SMILES: [AsH3]
Standard InChI: InChI=1S/AsH3/h1H3
Standard InChI Key: RBFQJDQYXXHULB-UHFFFAOYSA-N
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Natural Product: No | Oral: No | Chemical Probe: No | Parenteral: No |
| Molecule Type: Small molecule | Topical: No | First In Class: No | Black Box: No |
| Chirality: Yes | Availability: No | Prodrug: No |
| MESH ID | MESH Heading | EFO IDs | EFO Terms | Max Phase for Indication | References |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Molecular Weight: 77.95 | Molecular Weight (Monoisotopic): 77.9451 | AlogP: ┄ | #Rotatable Bonds: ┄ |
| Polar Surface Area: ┄ | Molecular Species: ┄ | HBA: ┄ | HBD: ┄ |
| #RO5 Violations: ┄ | HBA (Lipinski): ┄ | HBD (Lipinski): ┄ | #RO5 Violations (Lipinski): ┄ |
| CX Acidic pKa: ┄ | CX Basic pKa: ┄ | CX LogP: ┄ | CX LogD: ┄ |
| Aromatic Rings: ┄ | Heavy Atoms: ┄ | QED Weighted: ┄ | Np Likeness Score: ┄ |
| 1. Liu J, Liu Y, Powell DA, Waalkes MP, Klaassen CD.. (2002) Multidrug-resistance mdr1a/1b double knockout mice are more sensitive than wild type mice to acute arsenic toxicity, with higher arsenic accumulation in tissues., 170 (1): [PMID:11750083] [10.1016/s0300-483x(01)00532-7] |
| 2. Unpublished dataset, |
| 3. Unpublished dataset, |
| 4. Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.. (2004) [Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs]., 28 (8-9): [PMID:15646539] [10.1016/s0399-8320(04)95062-2] |
| 5. British National Formulary (72nd edition), |
| 6. Unpublished dataset, |
Source(5):
