ID: ALA1368

Max Phase: Approved

First Approval: 1983

Molecular Formula: H2NaO4P

Molecular Weight: 119.98

Molecule Type: Small molecule

Representations

Synonyms (15): Monosodium phosphate | Monosodium phosphate, anhydrous | Sodium acid phosphate | Sodium biphosphate | Sodium biphosphate, anhydrous | Sodium dihydrogen phosphate | Sodium orthophosphate monobasic | Sodium phosphate monobasic | Sodium phosphate monobasic (anhydrous) | Sodium phosphate, monobasic | Sodium phosphate,monobasic | Sodium primary phosphate | E-339(I) | INS NO.339(I) | INS-339(I)
Synonyms from Alternative Forms(15):

Trade Names(3): Ionosol B | Ionosol Mb | Ionosol T

Canonical SMILES:  O=P([O-])(O)O.[Na+]

Standard InChI:  InChI=1S/Na.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

Standard InChI Key:  AJPJDKMHJJGVTQ-UHFFFAOYSA-M

Molecule Features

Natural Product: No

Oral: Yes

Chemical Probe: No

Parenteral: Yes

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: Yes

Availability: Yes

Prodrug: No

Properties

Molecular Weight: 119.98

Molecular Weight (Monoisotopic): 119.9588

AlogP:

#Rotatable Bonds:

Polar Surface Area:

Molecular Species:

HBA:

HBD:

#RO5 Violations:

HBA (Lipinski):

HBD (Lipinski):

#RO5 Violations (Lipinski):

CX Acidic pKa:

CX Basic pKa:

CX LogP:

CX LogD:

Aromatic Rings:

Heavy Atoms:

QED Weighted:

Np Likeness Score:

References

1. Rusconi S, Innocenti A, Vullo D, Mastrolorenzo A, Scozzafava A, Supuran CT..  (2004)  Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet.,  14  (23): [PMID:15501037] [10.1016/j.bmcl.2004.09.064]

2. Unpublished dataset, 

3. USP Dictionary of USAN and International Names (2010 edition) and USAN registrations 2007-date, 

4. Unpublished dataset, 

Source

Source(4):

• Scientific Literature
• Clinical Candidates
• FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book)
• USP Dictionary of USAN and International Drug Names