4-Sulfo-phenyl-chloronium; GENERIC INORGANIC ANION

Alternative Forms

SLC16A3 Tchem Monocarboxylate transporter 4 (196 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc16a7 Monocarboxylate transporter 2 (30 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc16a1 Monocarboxylate transporter 1 (151 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rnt Ribonuclease T (18 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

crn-4 Cell death-related nuclease 4 (18 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Natural Product: No	Oral: No	Chemical Probe: No	Parenteral: No
Molecule Type: Small molecule	Topical: No	First In Class: No	Black Box: No
Chirality: No	Availability: No	Prodrug: No

MESH ID	MESH Heading	EFO IDs	EFO Terms	Max Phase for Indication	References

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Molecular Weight: 393.21	Molecular Weight (Monoisotopic): 393.9354	AlogP: ┄	#Rotatable Bonds: ┄
Polar Surface Area: ┄	Molecular Species: ┄	HBA: ┄	HBD: ┄
#RO5 Violations: ┄	HBA (Lipinski): ┄	HBD (Lipinski): ┄	#RO5 Violations (Lipinski): ┄
CX Acidic pKa: ┄	CX Basic pKa: ┄	CX LogP: ┄	CX LogD: ┄
Aromatic Rings: ┄	Heavy Atoms: ┄	QED Weighted: ┄	Np Likeness Score: ┄

1. Banks RB, Smith TJ, Hanna PE.. (1983) N-arylhydroxamic acid N,O-acyltransferase. Positional requirements for the substrate hydroxyl group., 26 (12): [PMID:6644748] [10.1021/jm00366a026]
2. Bröer S, Bröer A, Schneider HP, Stegen C, Halestrap AP, Deitmer JW.. (1999) Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes., 341 (1): [PMID:10417314] [10.1042/0264-6021:3410529]
3. Bröer S, Rahman B, Pellegri G, Pellerin L, Martin JL, Verleysdonk S, Hamprecht B, Magistretti PJ.. (1997) Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons., 272 (1): [PMID:9374487] [10.1074/jbc.272.48.30096]
4. Manning Fox JE, Meredith D, Halestrap AP.. (2000) Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle., 529 (1): [PMID:11101640] [10.1111/j.1469-7793.2000.00285.x]
5. Huang KW, Hsu KC, Chu LY, Yang JM, Yuan HS, Hsiao YY.. (2016) Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)., 59 (17): [PMID:27529560] [10.1021/acs.jmedchem.6b00794]

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